Louise Cooley
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View article: Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs – bloodstream infections and antimicrobial resistance patterns in Australian children and adolescents, January 2022 – December 2023
Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs – bloodstream infections and antimicrobial resistance patterns in Australian children and adolescents, January 2022 – December 2023 Open
Between January 2022 and December 2023, there were 1,827 bloodstream infection (BSI) isolates in 1,745 children and adolescents reported to the Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs, with 40% of …
View article: Communicable diseases genomics network: promoting and harmonising pathogen genomics implementation for public health in Australia
Communicable diseases genomics network: promoting and harmonising pathogen genomics implementation for public health in Australia Open
Globally, the utility of pathogen genomics for public health was highlighted by the COVID-19 pandemic. Approaches to enhance coordination and improve implementation of pathogen genomics for public health are needed. The Communicable Diseas…
View article: Effects of Decentralized Sequencing on National <i>Listeria monocytogenes</i> Genomic Surveillance, Australia, 2016–2023
Effects of Decentralized Sequencing on National <i>Listeria monocytogenes</i> Genomic Surveillance, Australia, 2016–2023 Open
We assessed turnaround times in the national Listeria monocytogenes genomic surveillance system in Australia before and after decentralized sequencing. Using 1,204 samples collected during 2016-2023, we observed statistically significant r…
View article: P-812. Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021
P-812. Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021 Open
Background The incidence, risks and organisms causing bloodstream infections (BSI) differ between children and adults due to distinct comorbidities, procedures and antibiotic exposures. Age-specific data are required to inform targeted int…
View article: Targeted Culture-Independent Sequencing Identifies Emergence of Macrolide-Resistant<i>Bordetella Pertussis</i>in Australia
Targeted Culture-Independent Sequencing Identifies Emergence of Macrolide-Resistant<i>Bordetella Pertussis</i>in Australia Open
Bordetella pertussis continues to circulate globally despite wide-spread vaccination, with an emergent international epidemic in 2024. The resurgence of disease is confounded by the emergence of pertactin-deficient, macrolide-resistant B. …
View article: <i>Vibrio parahaemolyticus</i> Foodborne Illness Associated with Oysters, Australia, 2021–2022
<i>Vibrio parahaemolyticus</i> Foodborne Illness Associated with Oysters, Australia, 2021–2022 Open
The bacterium Vibrio parahaemolyticus is ubiquitous in tropical and temperate waters throughout the world and causes infections in humans resulting from water exposure and from ingestion of contaminated raw or undercooked seafood, such as …
View article: Australian Group on Antimicrobial Research surveillance outcome programs – bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 – December 2021
Australian Group on Antimicrobial Research surveillance outcome programs – bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 – December 2021 Open
From 1 January 2020 to 31 December 2021, thirty-eight institutions across Australia submitted data to the Australian Group on Antimicrobial Resistance (AGAR) from patients aged < 18 years (AGAR-Kids). Over the two years, 1,679 isolates wer…
View article: Genomic Surveillance of Invasive Meningococcal Disease During a National MenW Outbreak in Australia, 2017–2018
Genomic Surveillance of Invasive Meningococcal Disease During a National MenW Outbreak in Australia, 2017–2018 Open
Background In Australia, invasive meningococcal disease (IMD) incidence rapidly increased between 2014 and 2017 due to rising serogroup W (MenW) and MenY infections. We aimed to better understand the genetic diversity of IMD during 2017 an…
View article: Effect of molnupiravir on SARS-CoV-2 evolution in immunocompromised patients: a retrospective observational study
Effect of molnupiravir on SARS-CoV-2 evolution in immunocompromised patients: a retrospective observational study Open
Australian Research Council.
View article: Current Epidemiology and Clinical Features of <i>Cryptococcus</i> Infection in Patients Without Human Immunodeficiency Virus: A Multicenter Study in 46 Hospitals in Australia and New Zealand
Current Epidemiology and Clinical Features of <i>Cryptococcus</i> Infection in Patients Without Human Immunodeficiency Virus: A Multicenter Study in 46 Hospitals in Australia and New Zealand Open
Background Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics of cryptococcosis in these patients remains incomplete. Methods We conducted a ret…
View article: A multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of <i>Staphylococcus aureus</i>
A multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of <i>Staphylococcus aureus</i> Open
Objectives There is clinical uncertainty over the optimal treatment for penicillin-susceptible Staphylococcus aureus (PSSA) infections. Furthermore, there is concern that phenotypic penicillin susceptibility testing methods are not reliabl…
View article: Time-to-positivity in bloodstream infection for <i>Candida</i> species as a prognostic marker for mortality
Time-to-positivity in bloodstream infection for <i>Candida</i> species as a prognostic marker for mortality Open
Time-to-positivity (TTP) may assist in predicting the outcome of candidaemia. We analysed a candidaemia dataset collected prospectively in Australia over 1 year (2014–2015). TTP was defined as the period from blood culture sampling to the …
View article: Evaluation of the Abbott Panbio™ COVID-19 Ag Rapid Antigen Test for Asymptomatic Patients during the Omicron Wave
Evaluation of the Abbott Panbio™ COVID-19 Ag Rapid Antigen Test for Asymptomatic Patients during the Omicron Wave Open
Rapid antigen testing (RAT) is a cost-effective and time-efficient method of identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and therefore a critical part of infection control strategies. There is no published evid…
View article: Serology study of healthcare workers following a hospital-based outbreak of COVID-19 in North West Tasmania, Australia, 2020
Serology study of healthcare workers following a hospital-based outbreak of COVID-19 in North West Tasmania, Australia, 2020 Open
Introduction Healthcare facilities are high-risk settings for coronavirus disease 2019 (COVID-19) transmission. Early in the COVID-19 pandemic, the first large healthcare-associated outbreak within Australia occurred in Tasmania. Several o…
View article: Antiviral treatments lead to the rapid accrual of hundreds of SARS-CoV-2 mutations in immunocompromised patients
Antiviral treatments lead to the rapid accrual of hundreds of SARS-CoV-2 mutations in immunocompromised patients Open
The antiviral Molnupiravir (Lageviro) is widely used across the world to treat SARS-CoV-2 infection. Molnupiravir reduces viral replication by inducing mutations throughout the genome, yet in patients that do not clear the infection, the l…
View article: Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2019: the Influenza Complications Alert Network FluCAN
Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2019: the Influenza Complications Alert Network FluCAN Open
Influenza is a common cause of acute respiratory infection, and is a major cause of morbidity and mortality. This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2019 influenza season. …
View article: Surveillance for severe influenza and COVID-19 in patients admitted to sentinel Australian hospitals in 2020: the Influenza Complications Alert Network (FluCAN)
Surveillance for severe influenza and COVID-19 in patients admitted to sentinel Australian hospitals in 2020: the Influenza Complications Alert Network (FluCAN) Open
Introduction Influenza is a common cause of acute respiratory infection, and is a major cause of morbidity and mortality. Coronavirus disease 2019 (COVID-19) is an acute respiratory infection that emerged as a pandemic worldwide before the…
View article: Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021
Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021 Open
Patients with haematological malignancies, haemopoietic stem cell transplant recipients and patients requiring admission to intensive care settings are at high risk for invasive candidiasis (IC). Over the past decade, there has been increa…
View article: Corrigendum: Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes
Corrigendum: Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes Open
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our princi…
View article: COVID-19: Integrating genomic and epidemiological data to inform public health interventions and policy in Tasmania, Australia
COVID-19: Integrating genomic and epidemiological data to inform public health interventions and policy in Tasmania, Australia Open
Objective: We undertook an integrated analysis of genomic and epidemiological data to investigate a large healthcare-associated COVID-19 outbreak and to better understand the epidemiology of all COVID-19 cases in Tasmania, Australia. Metho…
View article: Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes (vol 6, mgen000405, 2021)
Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes (vol 6, mgen000405, 2021) Open
In the published version of Supplementary Dataset 1 associated with this article and hosted on figshare at https://doi.org/10.6084/ m9.figshare.12545957.v2, there was an error in the listing of the NTHi isolate on line 551. ‘RHH-3’…
View article: Aminoglycoside use in paediatric febrile neutropenia – Outcomes from a nationwide prospective cohort study
Aminoglycoside use in paediatric febrile neutropenia – Outcomes from a nationwide prospective cohort study Open
Aminoglycosides are commonly prescribed to children with febrile neutropenia (FN) but their impact on clinical outcomes is uncertain and extent of guideline compliance is unknown. We aimed to review aminoglycoside prescription and addition…
View article: Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes
Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes Open
Nontypeable Haemophilus influenzae (NTHi) colonizes human upper respiratory airways and plays a key role in the course and pathogenesis of acute exacerbations of chronic obstructive pulmonary disease (COPD). Currently, it is not possible t…