Louise Falzon
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View article: A rapid review of the causes of diagnostic and treatment delays for tuberculosis in low-burden countries
A rapid review of the causes of diagnostic and treatment delays for tuberculosis in low-burden countries Open
Background Delays in diagnosing and treating tuberculosis (TB) have significant implications. We undertook a rapid review to explore factors associated with delays at all stages of the diagnostic and treatment pathways in low-burden settin…
View article: The diagnostic accuracy of ultrasound and genomic tests for the diagnosis of autosomal-dominant polycystic kidney disease: a systematic mapping review
The diagnostic accuracy of ultrasound and genomic tests for the diagnosis of autosomal-dominant polycystic kidney disease: a systematic mapping review Open
Background Genomic and ultrasound tests can provide diagnostic and prognostic information on autosomal-dominant polycystic kidney disease (ADPKD), and can screen first-degree relatives in whom early diagnosis can be advantageous. We conduc…
View article: Definitions of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group
Definitions of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group Open
Objective To systematically assess the evidence on the use of ultrasonography (US) for the detection of vascular inflammation in Takayasu arteritis (TAK), with a focus on evaluating existing scoring systems and identifying elementary sonog…
View article: An international compendium of health state utilities in people with HIV: a systematic review
An international compendium of health state utilities in people with HIV: a systematic review Open
Greater clarity in treatment regimens, preference-weighting methods, and different HIV clinical stages could improve interpretation and applicability of HSUVs in economic models. Despite this, our compendium and taxonomy of HSUVs can infor…
View article: Research culture influences in health and biomedical research: rapid scoping review and content analysis
Research culture influences in health and biomedical research: rapid scoping review and content analysis Open
The wide range of research culture influences in the recent literature indicates the need for coordinated and sustained research culture conversations. Core principles in effective research environments should include inclusive collaborati…
View article: Yet another problem with systematic reviews: a living review update
Yet another problem with systematic reviews: a living review update Open
This living review has captured an emerging theme in the published literature relating to the composition of the review author team and highlights a potential effect on the equity reporting of the systematic reviews. We recommend that meta…
View article: Systematic literature review to inform the Portuguese recommendations for the management of Raynaud’s phenomenon and digital ulcers in systemic sclerosis and other connective tissue diseases
Systematic literature review to inform the Portuguese recommendations for the management of Raynaud’s phenomenon and digital ulcers in systemic sclerosis and other connective tissue diseases Open
Objective: To perform a systematic literature review (SLR) aimed at evaluating the efficacy and safety of pharmacological and non-pharmacological treatments for Raynaud's phenomenon (RP) and digital ulcers (DU) in patients with systemic sc…
View article: Performance of clinical, laboratory and imaging features for diagnosing spondyloarthritis—a systematic literature review and meta-analysis
Performance of clinical, laboratory and imaging features for diagnosing spondyloarthritis—a systematic literature review and meta-analysis Open
Objective The Berlin algorithm was developed to help diagnose axial SpA (axSpA), but new studies suggest some features typical of SpA are less specific than previously assumed. Furthermore, evidence is lacking for other SpA subtypes (e.g. …
View article: Evaluation of a short training course of chest X-ray interpretation for the diagnosis of paediatric TB
Evaluation of a short training course of chest X-ray interpretation for the diagnosis of paediatric TB Open
BACKGROUNDChest X-ray (CXR) interpretation is challenging for the diagnosis of paediatric TB. We assessed the performance of a three half-day CXR training module for healthcare workers (HCWs) at low healthcare levels in six high TB inciden…
View article: Evidence on treat to target strategies in polymyalgia rheumatica and giant cell arteritis: a systematic literature review
Evidence on treat to target strategies in polymyalgia rheumatica and giant cell arteritis: a systematic literature review Open
Objectives To inform an international task force about current evidence on Treat to Target (T2T) strategies in PMR and GCA. Methods A systematic literature research (SLR) was conducted in Medline, EMBASE, Cochrane Library, clinicaltrials.g…
View article: Imaging in diagnosis, monitoring and outcome prediction of large vessel vasculitis: a systematic literature review and meta-analysis informing the 2023 update of the EULAR recommendations
Imaging in diagnosis, monitoring and outcome prediction of large vessel vasculitis: a systematic literature review and meta-analysis informing the 2023 update of the EULAR recommendations Open
Objectives To update the evidence on imaging for diagnosis, monitoring and outcome prediction in large vessel vasculitis (LVV) to inform the 2023 update of the European Alliance of Associations for Rheumatology recommendations on imaging i…
View article: The problems with systematic reviews: a living systematic review
The problems with systematic reviews: a living systematic review Open
Many hundreds of articles highlight that there are many flaws in the conduct, methods, and reporting of published systematic reviews, despite the existence and frequent application of guidelines. Considering the pivotal role that systemati…
View article: Non-pharmacological interventions to promote work participation in people with rheumatic and musculoskeletal diseases: a systematic review and meta-analysis from the EULAR taskforce on healthy and sustainable work participation
Non-pharmacological interventions to promote work participation in people with rheumatic and musculoskeletal diseases: a systematic review and meta-analysis from the EULAR taskforce on healthy and sustainable work participation Open
Objective To summarise the evidence on effectiveness of non-pharmacological (ie, non-drug, non-surgical) interventions on work participation (sick leave, work status and presenteeism) in people with rheumatic and musculoskeletal diseases (…
View article: Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis
Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis Open
CRD42021257588.
View article: Treating spondyloarthritis early: does it matter? Results from a systematic literature review
Treating spondyloarthritis early: does it matter? Results from a systematic literature review Open
Objective To summarize evidence on the relationship between early treatment (definition based on symptom/disease duration or radiographic damage) and treatment clinical response in patients with SpA. Methods A systematic literature review …
View article: A Series of Virtual Interventions for Chronic Lower Back Pain: A Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials
A Series of Virtual Interventions for Chronic Lower Back Pain: A Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials Open
Chronic lower back pain (CLBP) affects 25% of U.S. adults and is associated with high costs due to physician visits and reduced productivity. Research shows that massage and yoga can be effective nonpharmacological treatments for CLBP, but…
View article: Effectiveness of remote care interventions: a systematic review informing the 2022 EULAR Points to Consider for remote care in rheumatic and musculoskeletal diseases
Effectiveness of remote care interventions: a systematic review informing the 2022 EULAR Points to Consider for remote care in rheumatic and musculoskeletal diseases Open
Objective To perform a systematic literature review (SLR) on different outcomes of remote care compared with face-to-face (F2F) care, its implementation into clinical practice and to identify drivers and barriers in order to inform a task …
View article: Work participation in patients with systematic lupus erythematosus: a systematic review
Work participation in patients with systematic lupus erythematosus: a systematic review Open
Objectives This systematic review assessed which variables are associated with or are predictors for work participation outcomes in patients with systematic lupus erythematosus (SLE). Methods A literature search using MEDLINE, The Cochrane…
View article: Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider Open
Objectives To summarise current data on the value of imaging to guide interventional procedures in patients with rheumatic and musculoskeletal disease (RMDs) informing an European Alliance of Associations for Rheumatology taskforce. Method…
View article: EULAR portfolio for Rheumatology training: a EULAR School of Rheumatology initiative
EULAR portfolio for Rheumatology training: a EULAR School of Rheumatology initiative Open
Objective About half of the rheumatology trainees do not use a portfolio. This project was established to reach consensus about the content of a EULAR portfolio for Rheumatology training and subsequently develop portfolio assessment forms.…
View article: Methodological aspects of design, analysis and reporting of studies with work participation as an outcome domain in patients with inflammatory arthritis: results of two systematic literature reviews informing EULAR points to consider
Methodological aspects of design, analysis and reporting of studies with work participation as an outcome domain in patients with inflammatory arthritis: results of two systematic literature reviews informing EULAR points to consider Open
Objective To summarise the methodological aspects in studies with work participation (WP) as outcome domain in inflammatory arthritis (IA) and other chronic diseases. Methods Two systematic literature reviews (SLRs) were conducted in key e…
View article: Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a systematic literature research
Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a systematic literature research Open
Objectives Review of efficacy and safety of Janus kinase (JAK) inhibition in immune-mediated inflammatory diseases (IMIDs). Methods A systematic literature research (SLR) of all publications on JAK inhibitors (JAKi) treatment published unt…