Hui Qi Low
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View article: Setting analytical performance specification by simulation (Milan model 1b)
Setting analytical performance specification by simulation (Milan model 1b) Open
There is presently no consensus on the acceptable reclassification rate (or other clinical performance criterion), which challenges the development of model 1b analytical performance specifications (APS). Here, simulations were performed o…
View article: Sigma metric is more correlated with analytical imprecision than bias
Sigma metric is more correlated with analytical imprecision than bias Open
Routine laboratory performance can be assessed by external quality assurance (EQA) programs. The relative bias of the laboratory is assessed against a target value, which may be defined by a higher order method or peer-mean/median. The imp…
View article: Decoding violence against women: analysing harassment in middle eastern literature with machine learning and sentiment analysis
Decoding violence against women: analysing harassment in middle eastern literature with machine learning and sentiment analysis Open
The rising prevalence of harassment in Middle Eastern countries is mirrored in literary works from the region. However, extracting data from these texts to understand the typology and frequency of the cases poses a significant challenge du…
View article: Genome-wide association study of Parkinson’s disease in East Asians
Genome-wide association study of Parkinson’s disease in East Asians Open
Genome-wide association studies (GWAS) on Parkinson's disease (PD) have mostly been done in Europeans and Japanese. No study has been done in Han Chinese, which make up nearly a fifth of the world population. We conducted the first Han Chi…
View article: Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility Open
Psoriasis is a common inflammatory skin disease with complex genetics and different degrees of prevalence across ethnic populations. Here we present the largest trans-ethnic genome-wide meta-analysis (GWMA) of psoriasis in 15,369 cases and…