Luan Henrique Vasconcelos Alves
YOU?
Author Swipe
View article: IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model
IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model Open
Smoking remains the main risk factor for the development of chronic obstructive pulmonary disease (COPD). The inflammatory response mediated by innate and adaptive immune cells has been described in the development and progression of the d…
View article: Cigarette Smoke Exposure Leads to Organic and Mineral Bone Component Changes: The Importance of Rho Kinase Function in These Events
Cigarette Smoke Exposure Leads to Organic and Mineral Bone Component Changes: The Importance of Rho Kinase Function in These Events Open
Aberrant Rho-associated kinase function could be associated with increased bone fragility. Since cigarette smoke (CS) exposure promotes the increase in bone fragility due to changes in bone tissue components, this study aimed to investigat…
View article: Effect of exercise training on modulating the TH17/TREG imbalance in individuals with severe COPD: A randomized controlled trial
Effect of exercise training on modulating the TH17/TREG imbalance in individuals with severe COPD: A randomized controlled trial Open
Exercise training improved functional exercise capacity, muscle strength, and physical fitness, which was associated with a decrease in the Th17 inflammatory response and an increase in Treg cell phenotypes immunosuppressive activity.
View article: Phenotypes of regulatory T cells in different stages of COPD
Phenotypes of regulatory T cells in different stages of COPD Open
Despite the increase in both total Treg cells and the rTreg phenotype from the early stages of COPD, there was a decrease in cells expressing IL-10, suggesting a failure in controlling the inflammatory process. These events precede the pro…
View article: Phenotypes of Regulatory T Cells in Different Stages of Copd
Phenotypes of Regulatory T Cells in Different Stages of Copd Open
View article: Increased bone resorption by long-term cigarette smoke exposure in animal model
Increased bone resorption by long-term cigarette smoke exposure in animal model Open
These findings reinforce the importance of CS-induced oxidative stress in bone compromising the bone cellular activities with a consequent impairment in bone turn over and changes in bone structure.
View article: Increased Bone Resorption by Long-Term Cigarette Smoke Exposure in Animal Model
Increased Bone Resorption by Long-Term Cigarette Smoke Exposure in Animal Model Open