Luba Nemerovsky
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View article: The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities
The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities Open
Following administration of the SARS-CoV-2 vaccine, many women worldwide reported short-term menstrual irregularities. Although menstrual bleeding, “the fifth vital sign”, is experienced by more than 300 million people on any given day wor…
View article: Two types of cleavage, from zygote to three cells, result in different clinical outcomes and should be treated differently
Two types of cleavage, from zygote to three cells, result in different clinical outcomes and should be treated differently Open
Research Question What is the utilization rate of embryos that exert inadequate zygote cleavage into three daughter cells? Design This study used a retrospective dataset from a single IVF Unit. A total of 3,060 embryos from 1,811 fresh IVF…
View article: Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria
Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria Open
This multi-center study evaluated a novel microscope system capable of quantitative phase microscopy (QPM) for label-free sperm-cell selection for intracytoplasmic sperm injection (ICSI). Seventy-three patients were enrolled in four in vit…
View article: Novel non-toxic technology of sperm selection for ICSI comply with WHO strict normal criteria for stained sperm cells
Novel non-toxic technology of sperm selection for ICSI comply with WHO strict normal criteria for stained sperm cells Open
The authors have requested that this preprint be removed from Research Square.
View article: P-204 The pattern of the zygote cleavage to three cells must be considered before embryo transfer
P-204 The pattern of the zygote cleavage to three cells must be considered before embryo transfer Open
Study question What is the clinical outcome of instant irregular cleavage (IDC) from zygote to three cells? Summary answer IDC embryos, did not develop to blastocysts and did not acieve pregnancy; FC embryos that reached blastocyst stage e…
View article: The Role of PEDF in Reproductive Aging of the Ovary
The Role of PEDF in Reproductive Aging of the Ovary Open
Reproductive aging is characterized by a decline in ovarian function and in oocytes’ quantity and quality. Pigment epithelium-derived factor (PEDF), a pivotal player in ovarian angiogenic and oxidative balance, was evaluated for its involv…
View article: Standardization of Post-Vitrification Human Blastocyst Expansion as a Tool for Implantation Prediction
Standardization of Post-Vitrification Human Blastocyst Expansion as a Tool for Implantation Prediction Open
The increased use of vitrified blastocysts has encouraged the development of various criteria for selecting the embryo most likely to implant. Post-thaw assessment methods and timetables vary among investigators. We investigated the predic…
View article: Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation
Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation Open
Fertilization triggers physiological degradation of maternal-mRNAs, which are then replaced by embryonic transcripts. Ample evidence suggests that Argonaut 2 (AGO2) is a possible post-fertilization regulator of maternal-mRNAs degradation; …
View article: Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity
Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity Open
Breast cancer is diagnosed in ~0.3% of pregnant women. Studies that have addressed gestational and neonatal outcomes of chemotherapy during pregnancy have demonstrated increased gestational complications including preeclampsia and intraute…
View article: Pigment epithelium-derived factor (PEDF) negates hyperandrogenic PCOS features
Pigment epithelium-derived factor (PEDF) negates hyperandrogenic PCOS features Open
Polycystic ovary syndrome (PCOS), one of the most common female endocrine disorder, is a prevalent cause of infertility. Hyperandrogenism is a key feature in PCOS and is correlated with increased expression of VEGF and cytokines in the ova…