Luc Rochette
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View article: Temperature profiling at the American WAKE ExperimeNt (AWAKEN): methodology and uncertainty quantification
Temperature profiling at the American WAKE ExperimeNt (AWAKEN): methodology and uncertainty quantification Open
We quantify the accuracy of the temperature profiling from ground-based spectral infrared radiance observations at AWAKEN. Results from pre-campaign tests and comparisons with in-situ ground-based and airborne sensors at AWAKEN indicate th…
View article: The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST): instrument design and signal processing
The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST): instrument design and signal processing Open
The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST) is a Fourier-transform spectrometer designed, fabricated, and sold by LR Tech Inc., which operates in the thermal infrared. When attached to its automated radiom…
View article: The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST): Instrument design and signal processing
The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST): Instrument design and signal processing Open
The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST) is a Fourier-transform spectrometer designed, fabricated, and sold by LR Tech Inc., which operates in the thermal infrared. When attached to its automated radiom…
View article: Proximal and distant expression of growth differentiation factor 15 (GDF15) correlate with neurological deficit following experimental ischemic stroke
Proximal and distant expression of growth differentiation factor 15 (GDF15) correlate with neurological deficit following experimental ischemic stroke Open
Background and purpose Growth differentiation factor 15 (GDF15) has emerged as a promising biomarker in cerebro-cardiovascular disease, particularly in acute and chronic inflammatory stress situations. However, understanding the origins, t…
View article: Short‐Term Postnatal Overfeeding Induces Long‐Lasting Cardiometabolic Syndrome in Mature and Old Mice Associated with Increased Sensitivity to Myocardial Infarction
Short‐Term Postnatal Overfeeding Induces Long‐Lasting Cardiometabolic Syndrome in Mature and Old Mice Associated with Increased Sensitivity to Myocardial Infarction Open
Scope Perinatal nutritional disturbances may “program” an increased cardio‐metabolic risk in adulthood; however, few experimental studies have explored their effects on mature and/or old animal. This study aims to investigate the influence…
View article: Growth/differentiation factor 15 (GDF15) expression in the heart after myocardial infarction and cardioprotective effect of pre-ischemic rGDF15 administration
Growth/differentiation factor 15 (GDF15) expression in the heart after myocardial infarction and cardioprotective effect of pre-ischemic rGDF15 administration Open
Growth/differentiation factor-15 (GDF15) is considered an unfavourable prognostic biomarker for cardiovascular disease in clinical data, while experimental studies suggest it has cardioprotective potential. This study focuses on the direct…
View article: Postnatal overfeeding in mice induces early lipidic changes in heart tissue and impacts cardiomyocyte proliferation
Postnatal overfeeding in mice induces early lipidic changes in heart tissue and impacts cardiomyocyte proliferation Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): French Federation of Cardiology Foundation of France Background Shortly after birth, cardiomyocytes lose their ability to proliferate to switc…
View article: Growth Differentiation Factor 15 (GDF15) Expression in the Heart After Myocardial Infarction and Cardioprotective Effect of Pre-Ischemic rGDF15 Administration
Growth Differentiation Factor 15 (GDF15) Expression in the Heart After Myocardial Infarction and Cardioprotective Effect of Pre-Ischemic rGDF15 Administration Open
Clinical data consider growth differentiation factor-15 GDF15 as a prognostically unfavourable biomarker in cardiovascular diseases, while experimental studies suggest its cardioprotective potential. This study focuses on the direct cardia…
View article: New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family Open
Sodium-glucose co-transporter inhibitors (SGLTis) are the latest class of anti-hyperglycemic agents. In addition to inhibiting the absorption of glucose by the kidney causing glycosuria, these drugs also demonstrate cardio-renal benefits i…
View article: FESSTVaL: The Field Experiment on Submesoscale Spatio-Temporal Variability in Lindenberg
FESSTVaL: The Field Experiment on Submesoscale Spatio-Temporal Variability in Lindenberg Open
Numerical weather prediction models operate on grid spacings of a few kilometers, where deep convection begins to become resolvable. Around this scale, the emergence of coherent structures in the planetary boundary layer, often hypothesize…
View article: Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology?
Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology? Open
Antioxidants in cancer therapy have been a hot topic in the medical field for 20 years. Antioxidants are able to reduce the risk of cancer formation by neutralizing free radicals. Protons (H+) and molecular hydrogen (H2) interact in the ce…
View article: Stress: Eight Decades after Its Definition by Hans Selye: “Stress Is the Spice of Life”
Stress: Eight Decades after Its Definition by Hans Selye: “Stress Is the Spice of Life” Open
July 1936: Hans Selye describes in 74 lines in the prestigious journal Nature a new concept: Stress [...]
View article: Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis
Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis Open
Regulated cell death (RCD) has a significant impact on development, tissue homeostasis, and the occurrence of various diseases. Among different forms of RCD, ferroptosis is considered as a type of reactive oxygen species (ROS)-dependent re…
View article: Coronary artery embolism and acute coronary syndrome: A critical appraisal of existing data
Coronary artery embolism and acute coronary syndrome: A critical appraisal of existing data Open
The occurrence of coronary artery embolism (CE) has been associated with various clinical conditions, including aortic and mitral prosthetic heart valve implantation, atrial fibrillation (AF), dilated cardiomyopathy, neoplasia, infective e…
View article: Involvement of Oxidative Stress in Protective Cardiac Functions of Calprotectin
Involvement of Oxidative Stress in Protective Cardiac Functions of Calprotectin Open
Calprotectin (CLP) belonging to the S-100 protein family is a heterodimeric complex (S100A8/S100A9) formed by two binding proteins. Upon cell activation, CLP stored in neutrophils is released extracellularly in response to inflammatory sti…
View article: Emerging New Biomarkers for Cardiovascular Disease
Emerging New Biomarkers for Cardiovascular Disease Open
In this Special Issue of the International Journal of Molecular Sciences, we include insightful reviews and research papers on the subject “Emerging New Biomarkers for Cardiovascular Disease” [...]
View article: Inhaled nitric oxide before induction of anesthesia in patients with pulmonary hypertension.
Inhaled nitric oxide before induction of anesthesia in patients with pulmonary hypertension. Open
The administration of inhaled nitric oxide with a face mask before anaesthesia induction is safe and effective method to reduce pulmonary hypertension. The oxygen and hyperoxia influences the systemic vascular resistance and peripheral oxy…
View article: Association between Serum Osteoprotegerin Levels and Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction
Association between Serum Osteoprotegerin Levels and Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction Open
Background. Osteoprotegerin (OPG), a glycoprotein of the tumour necrosis factor (TNF) superfamily, is one of the main biomarkers for vascular calcification. Aim. We aimed to evaluate the association between serum OPG levels and extent of c…
View article: GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of respiratory and cardiovascular diseases, known as coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes the structural proteins spike (S), envelope (E)…
View article: GDF15 and Cardiac Cells: Current Concepts and New Insights
GDF15 and Cardiac Cells: Current Concepts and New Insights Open
Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β (TGF-β) superfamily of proteins. Glial-derived neurotrophic factor (GDNF) family receptor α-like (GFRAL) is an endogenous receptor for GDF15 detected …
View article: Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection
Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection Open
Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in late December 2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global pandemic on 20 March 2020. Cardiovascular complications are rapidly …
View article: Coronary lesion complexity in patients with heterozygous familial hypercholesterolemia hospitalized for acute myocardial infarction: data from the RICO survey
Coronary lesion complexity in patients with heterozygous familial hypercholesterolemia hospitalized for acute myocardial infarction: data from the RICO survey Open
Background Although patients with familial heterozygous hypercholesterolemia (FH) have a high risk of early myocardial infarction (MI), the coronary artery disease (CAD) burden in FH patients with acute MI remains to be investigated. Metho…
View article: Antitumor Activity of Protons and Molecular Hydrogen: Underlying Mechanisms
Antitumor Activity of Protons and Molecular Hydrogen: Underlying Mechanisms Open
Understanding the structure and dynamics of the various hydrogen forms has been a subject of numerous studies. Protons (H+) and molecular hydrogen (H2) in the cell are critical in a wide variety of processes. A new cancer treatment uses H2…
View article: Skin Immunomodulation during Regeneration: Emerging New Targets
Skin Immunomodulation during Regeneration: Emerging New Targets Open
Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation activities. They orchestrate, through their exosome, the mechanisms assoc…
View article: The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review Open
This review was conducted to emphasize the complex interplay between atrial fibrillation (AF) and myocardial infraction (MI). In type 1 (T1) MI, AF is frequent and associated with excess mortality. Moreover, AF after hospital discharge for…
View article: Programming of Cardiovascular Dysfunction by Postnatal Overfeeding in Rodents
Programming of Cardiovascular Dysfunction by Postnatal Overfeeding in Rodents Open
Nutritional environment in the perinatal period has a great influence on health and diseases in adulthood. In rodents, litter size reduction reproduces the effects of postnatal overnutrition in infants and reveals that postnatal overfeedin…
View article: The Crosstalk of Adipose-Derived Stem Cells (ADSC), Oxidative Stress, and Inflammation in Protective and Adaptive Responses
The Crosstalk of Adipose-Derived Stem Cells (ADSC), Oxidative Stress, and Inflammation in Protective and Adaptive Responses Open
The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared …