Luca Bargelloni
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View article: Structural variant landscape provides insights into genome organisation and domestication in European seabass
Structural variant landscape provides insights into genome organisation and domestication in European seabass Open
Background Structural variants (SVs) are genetic polymorphisms including deletions, insertions, inversions, and duplications, with potential to influence traits through impacts on gene function and expression. SVs have not been widely util…
View article: Complex Sex Determination in the Grey Mullet Mugil cephalus Suggested by Individual Whole Genome Sequence Data
Complex Sex Determination in the Grey Mullet Mugil cephalus Suggested by Individual Whole Genome Sequence Data Open
Mugil cephalus is a cosmopolitan marine fish highly relevant from ecological and economic perspectives. Previous studies identified sex-associated variants in the follicle-stimulating hormone receptor (fshr) gene following an XX/XY sex det…
View article: Generating gnotobiotic bivalves: a new method on Manila clam ( <i>Ruditapes philippinarum</i> )
Generating gnotobiotic bivalves: a new method on Manila clam ( <i>Ruditapes philippinarum</i> ) Open
Understanding how microbiomes influence the physiology of animal hosts requires detailed mechanistic insights, often obtained through gnotobiological approaches. Model organisms are central to this research, offering key advantages such as…
View article: Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum Open
View article: Temporal profiling of host transcriptome highlights time- and tissue-dependent Interferon pathway activation in NNV-infected European sea bass
Temporal profiling of host transcriptome highlights time- and tissue-dependent Interferon pathway activation in NNV-infected European sea bass Open
View article: Transcriptomic and microbiota responses in Mytilus galloprovincialis exposed to environmental concentrations of caffeine and cocaine
Transcriptomic and microbiota responses in Mytilus galloprovincialis exposed to environmental concentrations of caffeine and cocaine Open
The contamination of marine ecosystems by pharmaceuticals is an increasing concern due to their persistence and widespread use. This study investigated, for the first time, the effects of cocaine (COC) and caffeine (CAF), alone and in comb…
View article: Signatures of Selection for Resistance/Tolerance to <i>Perkinsus olseni</i> in Grooved Carpet Shell Clam (<i>Ruditapes decussatus</i>) Using a Population Genomics Approach
Signatures of Selection for Resistance/Tolerance to <i>Perkinsus olseni</i> in Grooved Carpet Shell Clam (<i>Ruditapes decussatus</i>) Using a Population Genomics Approach Open
The grooved carpet shell clam ( Ruditapes decussatus ) is a bivalve of high commercial value distributed throughout the European coast. Its production has suffered a decline caused by different factors, especially by the parasite Perkinsus…
View article: Integrated functional genomic analysis identifies regulatory variants underlying a major QTL for disease resistance in European sea bass
Integrated functional genomic analysis identifies regulatory variants underlying a major QTL for disease resistance in European sea bass Open
Background Viral nervous necrosis (VNN) is an important viral disease threatening global aquaculture sustainability and affecting over 50 farmed and ecologically important fish species. A major QTL for resistance to VNN has been previously…
View article: Transcriptional modulation in Mediterranean Mussel Mytilus galloprovincialis following exposure to four pharmaceuticals widely distributed in coastal areas
Transcriptional modulation in Mediterranean Mussel Mytilus galloprovincialis following exposure to four pharmaceuticals widely distributed in coastal areas Open
View article: Population Genomics of the Blue Shark, <i>Prionace glauca</i>, Reveals Different Populations in the Mediterranean Sea and the Northeast Atlantic
Population Genomics of the Blue Shark, <i>Prionace glauca</i>, Reveals Different Populations in the Mediterranean Sea and the Northeast Atlantic Open
Populations of marine top predators have been sharply declining during the past decades, and one‐third of chondrichthyans are currently threatened with extinction. Sustainable management measures and conservation plans of large pelagic sha…
View article: Integrated functional genomic analysis identifies the regulatory variants underlying a major QTL for disease resistance in European sea bass
Integrated functional genomic analysis identifies the regulatory variants underlying a major QTL for disease resistance in European sea bass Open
Background Viral nervous necrosis (VNN) is a viral disease threatening the sustainability of global aquaculture, and affecting over 50 of farmed and ecologically important species. A major QTL for resistance to VNN has been previously desc…
View article: Advancing fish breeding in aquaculture through genome functional annotation
Advancing fish breeding in aquaculture through genome functional annotation Open
View article: Multi-omics for studying and understanding polar life
Multi-omics for studying and understanding polar life Open
Polar ecosystems are experiencing amongst the most rapid rates of regional warming on Earth. Here, we discuss ‘omics’ approaches to investigate polar biodiversity, including the current state of the art, future perspectives and recommendat…
View article: A Weight of Evidence approach to support the assessment of the quality of Manila clam farming sites in a coastal lagoon
A Weight of Evidence approach to support the assessment of the quality of Manila clam farming sites in a coastal lagoon Open
View article: Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition
Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition Open
View article: Impaired reproduction, energy reserves and dysbiosis: The overlooked consequences of heatwaves in a bivalve mollusc
Impaired reproduction, energy reserves and dysbiosis: The overlooked consequences of heatwaves in a bivalve mollusc Open
Extreme events like Marine Heatwaves (MHWs) are becoming more intense, severe, and frequent, threatening benthic communities, specifically bivalves. However, the consequences of non-lethal MHWs on animals are still poorly understood. Here,…
View article: Evaluating <i>Escherichia coli</i> contamination in bivalve mollusks using the impedance method: a comparison with most probable number analyses and correlation with environmental parameters
Evaluating <i>Escherichia coli</i> contamination in bivalve mollusks using the impedance method: a comparison with most probable number analyses and correlation with environmental parameters Open
The application of an electrochemical (impedance) tool for monitoring Escherichia coli contamination in shellfish was evaluated after 13 months of observation. The primary aim of the present study was to compare the standard most probable …
View article: Transcriptional Profiling of Populations in the Clam Ruditapes decussatus Suggests Genetically Determined Differentiation in Gene Expression along Parallel Temperature Gradients and between Races of the Atlantic Ocean and West Mediterranean Sea
Transcriptional Profiling of Populations in the Clam Ruditapes decussatus Suggests Genetically Determined Differentiation in Gene Expression along Parallel Temperature Gradients and between Races of the Atlantic Ocean and West Mediterranean Sea Open
Ongoing ocean warming due to climate change poses new challenges for marine life and its exploitation. We have used transcriptomics to find genetically based responses to increased temperature in natural populations of the marine clam Rudi…
View article: Viral nervous necrosis resistance in gilthead sea bream (Sparus aurata) at the larval stage: heritability and accuracy of genomic prediction with different training and testing settings
Viral nervous necrosis resistance in gilthead sea bream (Sparus aurata) at the larval stage: heritability and accuracy of genomic prediction with different training and testing settings Open
Background The gilthead sea bream ( Sparus aurata ) has long been considered resistant to viral nervous necrosis (VNN), until recently, when significant mortalities caused by a reassortant nervous necrosis virus (NNV) strain were reported.…
View article: Transcriptional profiling of populations in the clam<i>Ruditapes decussatus</i>suggests genetically determined differentiation in gene-expression along parallel temperature gradients and between races of the Atlantic Ocean and West Mediterranean sea
Transcriptional profiling of populations in the clam<i>Ruditapes decussatus</i>suggests genetically determined differentiation in gene-expression along parallel temperature gradients and between races of the Atlantic Ocean and West Mediterranean sea Open
Ongoing ocean warming due to climate change poses new challenges for marine life and its exploitation. We have used transcriptomics to find genetically-based responses to increased temperature in natural populations of the marine clam Rudi…
View article: An innovative index to incorporate transcriptomic data into weight of evidence approaches for environmental risk assessment
An innovative index to incorporate transcriptomic data into weight of evidence approaches for environmental risk assessment Open
View article: Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs
Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs Open
Aquaporin-mediated oocyte hydration is considered important for the evolution of pelagic eggs and the radiative success of marine teleosts. However, the molecular regulatory mechanisms controlling this vital process are not fully understoo…
View article: Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma
Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma Open
Background: Mild equine asthma (MEA) and severe equine asthma (SEA) are two of the most frequent equine airway inflammatory diseases, but knowledge about their pathogenesis is limited. The goal of this study was to investigate gene express…
View article: Multidisciplinary long-term survey of Manila clam grown in farming sites subjected to different environmental conditions
Multidisciplinary long-term survey of Manila clam grown in farming sites subjected to different environmental conditions Open
View article: Multi-tissue RNA-Seq Analysis and Long-read-based Genome Assembly Reveal Complex Sex-specific Gene Regulation and Molecular Evolution in the Manila Clam
Multi-tissue RNA-Seq Analysis and Long-read-based Genome Assembly Reveal Complex Sex-specific Gene Regulation and Molecular Evolution in the Manila Clam Open
The molecular factors and gene regulation involved in sex determination and gonad differentiation in bivalve molluscs are unknown. It has been suggested that doubly uniparental inheritance (DUI) of mitochondria may be involved in these pro…
View article: Machine Learning and Canine Chronic Enteropathies: A New Approach to Investigate FMT Effects
Machine Learning and Canine Chronic Enteropathies: A New Approach to Investigate FMT Effects Open
Fecal microbiota transplantation (FMT) represents a very promising approach to decreasing disease activity in canine chronic enteropathies (CE). However, the relationship between remission mechanisms and microbiome changes has not been elu…
View article: Effects of environmental concentrations of the fragrance amyl salicylate on the mediterranean mussel Mytilus galloprovincialis
Effects of environmental concentrations of the fragrance amyl salicylate on the mediterranean mussel Mytilus galloprovincialis Open
View article: Molecular Monitoring of SARS-CoV-2 in Different Sewage Plants in Venice and the Implications for Genetic Surveillance
Molecular Monitoring of SARS-CoV-2 in Different Sewage Plants in Venice and the Implications for Genetic Surveillance Open
Wastewater-based epidemiology is now widely used as an indirect tool to monitor the spread of SARS-CoV-2. In this study, five different sample matrices representing diverse phases of the wastewater treatment process were collected during t…
View article: Population structure and genetic variability in wild and farmed Mediterranean populations of gilthead seabream and European seabass inferred from a 60K combined species SNP array
Population structure and genetic variability in wild and farmed Mediterranean populations of gilthead seabream and European seabass inferred from a 60K combined species SNP array Open
View article: Genomic Predictions of Phenotypes and Pseudo-Phenotypes for Viral Nervous Necrosis Resistance, Cortisol Concentration, Antibody Titer and Body Weight in European Sea Bass
Genomic Predictions of Phenotypes and Pseudo-Phenotypes for Viral Nervous Necrosis Resistance, Cortisol Concentration, Antibody Titer and Body Weight in European Sea Bass Open
In European sea bass (Dicentrarchus labrax L.), the viral nervous necrosis mortality (MORT), post-stress cortisol concentration (HC), antibody titer (AT) against nervous necrosis virus and body weight (BW) show significant heritability, wh…