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View article: A 20 MHz Repetition Rate, Sub-Picosecond Ti–Sapphire Laser for Fiber Delivery in Nonlinear Microscopy of the Skin
A 20 MHz Repetition Rate, Sub-Picosecond Ti–Sapphire Laser for Fiber Delivery in Nonlinear Microscopy of the Skin Open
Nonlinear microscopy (NM) enables us to investigate the morphology or monitor the physiological processes of the skin through the use of ultrafast lasers. Fiber (or fiber-coupled) lasers are of great interest because they can easily be com…
View article: A Cross-Sectional Study of the Dermatological Manifestations of Patients with Fabry Disease and the Assessment of Angiokeratomas with Multimodal Imaging
A Cross-Sectional Study of the Dermatological Manifestations of Patients with Fabry Disease and the Assessment of Angiokeratomas with Multimodal Imaging Open
Fabry disease (FD) is a multisystemic X-linked lysosomal storage disease that presents with angiokeratomas (AKs). Our objective was to investigate the clinical and morphologic features of AKs and to present two experimental techniques, mul…
View article: Scrofuloderma and granuloma annulare-like lesions: Challenges of diagnosing cutaneous tuberculosis in developed countries
Scrofuloderma and granuloma annulare-like lesions: Challenges of diagnosing cutaneous tuberculosis in developed countries Open
View article: Correlation of systemic involvement and presence of pathological skin calcification assessed by ex vivo nonlinear microscopy in Pseudoxanthoma elasticum
Correlation of systemic involvement and presence of pathological skin calcification assessed by ex vivo nonlinear microscopy in Pseudoxanthoma elasticum Open
View article: Clinical application of high-frequency ultrasound, optical coherence tomography and magnetic resonance imaging in dermatology
Clinical application of high-frequency ultrasound, optical coherence tomography and magnetic resonance imaging in dermatology Open
Dermoscopy is the most widely used noninvasive imaging method for the assessment of skin lesions. However, in recent years various other in vivo imaging modalities have made remarkable development. With the use of these novel methods, it i…
View article: Teledermatology: the new era of digitalization in dermatology care
Teledermatology: the new era of digitalization in dermatology care Open
There is a growing scope of different telemedicine modalities in patient care, especially with the development of various communication and digital imaging devices. In dermatology, there has been an unprecedented increase in the number of …
View article: Innovative in vivo imaging techniques in dermatology
Innovative in vivo imaging techniques in dermatology Open
As a result of advances in the development of medical imaging, the toolbox of dermatological imaging in the XXI. century expanded considerably. In addition to the histological examination that is currently the gold standard in diagnostics,…
View article: Emergency Use and Efficacy of an Asynchronous Teledermatology System as a Novel Tool for Early Diagnosis of Skin Cancer during the First Wave of COVID-19 Pandemic
Emergency Use and Efficacy of an Asynchronous Teledermatology System as a Novel Tool for Early Diagnosis of Skin Cancer during the First Wave of COVID-19 Pandemic Open
Background: After the outbreak of the corona virus disease-19 (COVID-19) pandemic, teledermatology was implemented in the Hungarian public healthcare system for the first time. Our objective was to assess aggregated diagnostic agreements a…
View article: 068 Association of systemic involvement with skin morphology assessed by multiphoton microscopy in pseudoxanthoma elasticum
068 Association of systemic involvement with skin morphology assessed by multiphoton microscopy in pseudoxanthoma elasticum Open
View article: 065 Application of teledermatology during the first wave of the COVID-19 pandemic in Hungary
065 Application of teledermatology during the first wave of the COVID-19 pandemic in Hungary Open
View article: Quantitative Multispectral Imaging Differentiates Melanoma from Seborrheic Keratosis
Quantitative Multispectral Imaging Differentiates Melanoma from Seborrheic Keratosis Open
Melanoma is a melanocytic tumor that is responsible for the most skin cancer-related deaths. By contrast, seborrheic keratosis (SK) is a very common benign lesion with a clinical picture that may resemble melanoma. We used a multispectral …
View article: Autofluorescence Imaging of the Skin Is an Objective Non-Invasive Technique for Diagnosing Pseudoxanthoma Elasticum
Autofluorescence Imaging of the Skin Is an Objective Non-Invasive Technique for Diagnosing Pseudoxanthoma Elasticum Open
Pseudoxanthoma elasticum (PXE) is a rare multisystemic autosomal recessive connective tissue disease. In most cases, skin manifestations of PXE are the first to develop, followed later by severe ocular and cardiovascular complications. In …
View article: Visualization of Keratin with Diffuse Reflectance and Autofluorescence Imaging and Nonlinear Optical Microscopy in a Rare Keratinopathic Ichthyosis
Visualization of Keratin with Diffuse Reflectance and Autofluorescence Imaging and Nonlinear Optical Microscopy in a Rare Keratinopathic Ichthyosis Open
Keratins are one of the main fluorophores of the skin. Keratinization disorders can lead to alterations in the optical properties of the skin. We set out to investigate a rare form of keratinopathic ichthyosis caused by KRT1 mutation with …
View article: Dermatologic aspects of bed bug epidemic: an atlas of differential diagnosis
Dermatologic aspects of bed bug epidemic: an atlas of differential diagnosis Open
Bed bug infestation rate has gone through an unforeseen increase in the past decades worldwide. Their resurgence is a consequence of numerous factors, including growing population density, increased international travel and the spread of i…
View article: 20 MHz, sub-ps, tunable ti:sapphire laser system for real time, stain free, in vivo histology of the skin
20 MHz, sub-ps, tunable ti:sapphire laser system for real time, stain free, in vivo histology of the skin Open
View article: Low concentration eosin staining for high chemical contrast nonlinear microscope mosaic imaging of skin alterations in Pseudoxanthoma elasticum
Low concentration eosin staining for high chemical contrast nonlinear microscope mosaic imaging of skin alterations in Pseudoxanthoma elasticum Open
IntroductionPseudoxanthoma elasticum (PXE, OMIM#264800) is an autosomal recessive metabolic disorder characterized by progressive ectopic mineralization of soft connective tissue [1].To date, diagnosis of PXE is confirmed with skin biopsy …
View article: Coronavirus disease 2019 in a psoriatic patient with concomitant chronic obstructive pulmonary disease under treatment with risankizumab
Coronavirus disease 2019 in a psoriatic patient with concomitant chronic obstructive pulmonary disease under treatment with risankizumab Open
The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request.
View article: Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticum
Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticum Open
View article: Hyperhidrosis: clinical classification and treatment options
Hyperhidrosis: clinical classification and treatment options Open
View article: Nonlinear microscopy for the visualization of calcification and assessment of connective tissue fibers in pseudoxanthoma elasticum
Nonlinear microscopy for the visualization of calcification and assessment of connective tissue fibers in pseudoxanthoma elasticum Open
Pseudoxanthoma elasticum (PXE, OMIM 264800) is a rare disorder caused by mutations of the ABCC6 gene in which decreased plasma levels of inorganic pyrophosphate (PPi) lead to ectopic mineralization resulting in severe dermatological, ophth…
View article: Novel imaging techniques and their clinical applications in the field of dermatology
Novel imaging techniques and their clinical applications in the field of dermatology Open
Az elmúlt évtizedekben az orvosi képalkotás fejlődése jelentős előrelépéseket hozott a bőrgyógyászatban.Bár jelenleg a hisztopatológiai vizsgálat az "arany standard" diagnosztikus módszer, a már-már szövettani felbontást lehetővé tévő in v…
View article: Genetic analysis and nonlinear opical imaging of vascular Ehlers-Danlos syndrome
Genetic analysis and nonlinear opical imaging of vascular Ehlers-Danlos syndrome Open
A szerzők a ritka, örökletes kötőszöveti betegségek közé tartozó, multidiszciplináris jelentőségű vascularis Ehlers-Danlos szindrómára vonatkozó korszerű ismereteket foglalják össze. A szindróma vezető tünetei -az ízületi hipermobilitás, a…
View article: Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects
Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects Open
Background: Smoothened receptor inhibitor vismodegib is indicated to treat locally advanced basal cell carcinoma (laBCC) and lesions in nevoid basal cell carcinoma syndrome (NBCCS).Methods: We treated 11 patients - including …
View article: Efficiency of long-term high-dose intravenous ascorbic acid therapy in locally advanced basal cell carcinoma – a pilot study
Efficiency of long-term high-dose intravenous ascorbic acid therapy in locally advanced basal cell carcinoma – a pilot study Open
Our results suggest that IVA is well tolerated in a small group of patients with extensive BCCs. However, in the era of smoothened (Smo) receptor inhibitors, it may only be considered as an adjuvant therapy in treatment-resistant cases.
View article: Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep
Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep Open
View article: Genetic background of malignant epidermal skin cancer and novel insights in the process of carcinogenesis
Genetic background of malignant epidermal skin cancer and novel insights in the process of carcinogenesis Open
A fehérbőrű populáció leggyakoribb rosszindulatú daganatai a bőrt érintik.Ezen belül is kiemelendő gyakoriságuk tekintetében a bazálsejtes-és a spinocelluláris karcinóma által alkotott hámeredetű bőrtumorok csoportja.Bár ezek mortalitása a…