Luca Luzzi
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View article: Lymph Node Involvement and Radiologic Predictors of Invasiveness in Pure Ground-Glass Adenocarcinomas: The GORDON Study
Lymph Node Involvement and Radiologic Predictors of Invasiveness in Pure Ground-Glass Adenocarcinomas: The GORDON Study Open
Adenocarcinomas presenting as pGGOs are low-risk lesions with rare lymph node involvement or recurrence, suggesting that lymphadenectomy may be unnecessary. Preoperative chest CT enables risk stratification of lesion invasiveness, supporti…
View article: Use of Normothermic Perfusion Machines in Lung Transplantation: Consensus Statement of the Italian Society of Organ and Tissues Transplantation Group With DELPHI Method
Use of Normothermic Perfusion Machines in Lung Transplantation: Consensus Statement of the Italian Society of Organ and Tissues Transplantation Group With DELPHI Method Open
Background Ex vivo lung perfusion (EVLP) is a technique for graft preservation, evaluation and treatment, that could expand donor pool for transplantation. Nevertheless, the wide spectrum of available platforms has generated disparities in…
View article: Assessing Short- and Medium-Term Outcomes of Lung Transplantation in Elderly Recipients: A Comparative Age-Based Analysis
Assessing Short- and Medium-Term Outcomes of Lung Transplantation in Elderly Recipients: A Comparative Age-Based Analysis Open
Background/Objectives: This study aims to analyze the short- and medium-term outcomes of lung transplantation (LT) in recipients aged 65 years and older, comparing them with those of younger individuals. The primary endpoints were 90-day a…
View article: From Sequence to Site: RNA Therapeutics and Direct Pulmonary Delivery in Lung Cancer
From Sequence to Site: RNA Therapeutics and Direct Pulmonary Delivery in Lung Cancer Open
More than three decades have passed since gene therapy potential was first recognized, following the first clinical trials, marking the beginning of a new era in targeted cancer therapy. Despite its early promise, the clinical development …
View article: Impact of donor-recipient ethnic matching on survival after lung transplantation in Italy
Impact of donor-recipient ethnic matching on survival after lung transplantation in Italy Open
Disparities in access to and outcomes of lung transplantation have been extensively studied in North America, but little is known about these disparities in Europe. This study evaluates the impact of ethnicity on lung transplantation outco…
View article: A Precision Surgery Framework for Lung Resection: Robotic, Video-Assisted, and Open Segmentectomy
A Precision Surgery Framework for Lung Resection: Robotic, Video-Assisted, and Open Segmentectomy Open
Objectives: To evaluate outcomes of patients undergoing lung segmentectomy using open thoracotomy, Video-Assisted Thoracoscopic Surgery (VATS), or Robotic-Assisted Thoracoscopic Surgery (RATS) approaches. Methods: A total of 157 patients (…
View article: Paravertebral Block and Perioperative Ketamine in an Opioid-Sparing Analgesia Approach in Video-Assisted Thoracic Surgery: A Retrospective Single-Centre Study
Paravertebral Block and Perioperative Ketamine in an Opioid-Sparing Analgesia Approach in Video-Assisted Thoracic Surgery: A Retrospective Single-Centre Study Open
Background: Regional anaesthesia techniques allow postoperative pain control while reducing opioid consumption. Ketamine is another viable option for minimising perioperative opioid use. We evaluated the efficacy of a perioperative multimo…
View article: Strategies for Maximising Lung Utilisation in Donors After Brain and Cardiac Death: A Narrative Review
Strategies for Maximising Lung Utilisation in Donors After Brain and Cardiac Death: A Narrative Review Open
Lung transplantation remains the standard of care for end-stage lung disease, yet a persistent gap exists between donor lung availability and growing clinical demand. Expanding the donor pool and optimising donor lung management are theref…
View article: Paravertebral Block and Perioperative Ketamine in an Opioid-Sparing Analgesia Approach in Thoracic Surgery: A Retrospective Single-Centre Study
Paravertebral Block and Perioperative Ketamine in an Opioid-Sparing Analgesia Approach in Thoracic Surgery: A Retrospective Single-Centre Study Open
Background: Regional anaesthesia techniques allow postoperative pain control while reducing opioid con-sumption. Ketamine is another viable option for minimising perioperative opioid use. We evaluated the ef-ficacy of a perioperative multi…
View article: Strategies for Maximising Lung Utilisation in Donors After Brain and Cardiac Death: A Narrative Review
Strategies for Maximising Lung Utilisation in Donors After Brain and Cardiac Death: A Narrative Review Open
Lung transplantation remains the standard of care for end-stage lung disease, yet a persistent gap exists between donor lung availability and growing clinical demand. Expanding the donor pool and optimising donor lung management are theref…
View article: Donor-Recipient Mismatch in Lung Transplantation: The Role of Graft Sizing in Clinical Outcomes
Donor-Recipient Mismatch in Lung Transplantation: The Role of Graft Sizing in Clinical Outcomes Open
Lung transplantation is a life-saving procedure for end-stage lung diseases. Size matching is critical in the donor-recipient selection process. This retrospective study analyzed 146 patients who underwent lung transplantation between 2013…
View article: Satisfactory outcome with robotic-assisted chest wall resection and reconstruction: a case report
Satisfactory outcome with robotic-assisted chest wall resection and reconstruction: a case report Open
Background: The surgical management of chest wall tumors is challenging, particularly in balancing effective resection with preserving structural integrity, minimizing postoperative morbidity. While traditional open thoracotomy has been th…
View article: Sarcoid Nodule or Lung Cancer? A High-Resolution Computed Tomography-Based Retrospective Study of Pulmonary Nodules in Patients with Sarcoidosis
Sarcoid Nodule or Lung Cancer? A High-Resolution Computed Tomography-Based Retrospective Study of Pulmonary Nodules in Patients with Sarcoidosis Open
Background: The objective of this retrospective study was to compare the characteristics of sarcoid nodules and neoplastic nodules using high-resolution computed tomography (HRCT) in sarcoidosis patients. Methods: This is a single-center r…
View article: Prevalence of concomitant aortic disease and lung cancer: an exploratory study
Prevalence of concomitant aortic disease and lung cancer: an exploratory study Open
Patients with lung cancer have a high prevalence of aortic disease, defining a peculiar subset of patients who deserve a specific protocol of treatment and follow-up. Further studies are needed to define a dedicated standardized multidisci…
View article: Robotic thymectomy in thymic tumours: a multicentre, nation-wide study
Robotic thymectomy in thymic tumours: a multicentre, nation-wide study Open
OBJECTIVES Robotic thymectomy has been suggested and considered technically feasible for thymic tumours. However, because of small-sample series and the lack of data on long-term results, controversies still exist on surgical and oncologic…
View article: Lung Resection for Non-Small Cell Lung Cancer following Bronchoscopic Lung Volume Reduction for Heterogenous Emphysema
Lung Resection for Non-Small Cell Lung Cancer following Bronchoscopic Lung Volume Reduction for Heterogenous Emphysema Open
Bronchoscopic lung volume reduction (BLVR) is a minimally invasive treatment for emphysema. Lung cancer may be associated with emphysema due to common risk factors. Thus, a growing number of patients undergoing BLVR may develop lung cancer…
View article: Lung Transplantation in Patients with Previous or Unknown Oncological Disease: Evaluation of Short- and Long-Term Outcomes
Lung Transplantation in Patients with Previous or Unknown Oncological Disease: Evaluation of Short- and Long-Term Outcomes Open
The accurate selection of the recipient is a crucial aspect in the field of lung transplantation (LTX), especially if patients were previously affected by oncological disease. The aim of this bicentric retrospective study was to evaluate s…
View article: Umanizzazione delle cure, non solo macchine ma anche persone
Umanizzazione delle cure, non solo macchine ma anche persone Open
This chapter written by different Authors claims and offers a new (yet ancient) view of medicine: the great knowledge of biomedical fields blended with treatment devoted to patient care as a person with a view to developing compliance betw…
View article: Coming Back to the Basics. Comment on Cangir et al. A CT-Based Radiomic Signature for the Differentiation of Pulmonary Hamartomas from Carcinoid Tumors. Diagnostics 2022, 12, 416
Coming Back to the Basics. Comment on Cangir et al. A CT-Based Radiomic Signature for the Differentiation of Pulmonary Hamartomas from Carcinoid Tumors. Diagnostics 2022, 12, 416 Open
We read with great interest the article by Cangir et al., “A CT-Based Radiomic Signature for the Differentiation of Pulmonary Hamartomas from Carcinoid Tumors”, published on 5 February 2022 [...]
View article: Outcomes of Induction Chemotherapy in Resectable NSCLC Treated with Radical Surgery: A Pre- and POST-Operative Prognostic Factors Analysis
Outcomes of Induction Chemotherapy in Resectable NSCLC Treated with Radical Surgery: A Pre- and POST-Operative Prognostic Factors Analysis Open
The aim of the study is to evaluate the predictive factors of response to induction chemotherapy in patients with resectable NSCLC, treated at the unit of Thoracic Surgery of Siena University Hospital with radical surgery. From January 1, …
View article: Malignant Pleural Mesothelioma: Preliminary Toxicity Results of Adjuvant Radiotherapy Hypofractionation in a Prospective Trial (MESO-RT)
Malignant Pleural Mesothelioma: Preliminary Toxicity Results of Adjuvant Radiotherapy Hypofractionation in a Prospective Trial (MESO-RT) Open
Malignant Pleural Mesothelioma (MPM) is a rare malignancy with an overall poor prognosis. The standard therapeutic strategy in early-stage disease is trimodality therapy. In this publication, we report the preliminary toxicity results of t…