Lucas Higuera
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View article: The use and ethical implications of artificial intelligence, collaboration, and participation in local Ibero-American newsrooms
The use and ethical implications of artificial intelligence, collaboration, and participation in local Ibero-American newsrooms Open
This study examined the use and ethical implications of Artificial Intelligence (AI), collaboration, and participation in 12 local Ibero-American news outlets across Brazil, Colombia, Ecuador, Spain, Mexico, Peru, and Portugal. Based on da…
View article: Impact of Artificial Intelligence-Enhanced Insertable Cardiac Monitors on Device Clinic Workflow and Resource Utilization
Impact of Artificial Intelligence-Enhanced Insertable Cardiac Monitors on Device Clinic Workflow and Resource Utilization Open
View article: Two-year outcomes of Micra AV leadless pacemakers in the Micra AV CED study
Two-year outcomes of Micra AV leadless pacemakers in the Micra AV CED study Open
Aims Leadless pacing is a safe and effective alternative to transvenous pacing for bradycardia. Micra AV is a leadless, single-device solution that provides atrioventricular synchronous ventricular pacing therapy. Early results from the Mi…
View article: Assessment of the E-value in the presence of bias amplification: a simulation study
Assessment of the E-value in the presence of bias amplification: a simulation study Open
View article: Association Between use of an Adaptive Cardiac Resynchronization Therapy Algorithm and Healthcare Utilization and Cost
Association Between use of an Adaptive Cardiac Resynchronization Therapy Algorithm and Healthcare Utilization and Cost Open
Objectives To assess the association between use of adaptive pacing on clinical and economic outcomes of CRT recipients in real-world analysis. Background The AdaptivCRT TM algorithm was shown in prior subgroup analyses of prospective tria…
View article: Outcomes of patients implanted with an atrioventricular synchronous leadless ventricular pacemaker in the Medicare population
Outcomes of patients implanted with an atrioventricular synchronous leadless ventricular pacemaker in the Medicare population Open
Patients implanted with Micra AV had similar rates of complications at 30 days and significantly lower rates of complications and reinterventions at 6 months, despite being sicker than patients implanted with a transvenous pacemaker.
View article: POS0986-PARE IMPACT OF EDUCATIONAL CAMPAIGNS ON RMD IN SOCIAL NETWORKS
POS0986-PARE IMPACT OF EDUCATIONAL CAMPAIGNS ON RMD IN SOCIAL NETWORKS Open
Background Panama's prevalence of rheumatoid arthritis lies within the global range (.24 to 1%). To improve the quality of life of RMD patients in the country, FUNARP was created over 18 years ago to educate and support patients, caregiver…
View article: CI-452768-4 THE MICRA AV LEADLESS PACEMAKER IN THE REAL-WORLD MEDICARE POPULATION: EARLY RESULTS FROM THE MICRA AV COVERAGE WITH EVIDENCE DEVELOPMENT (CED) STUDY
CI-452768-4 THE MICRA AV LEADLESS PACEMAKER IN THE REAL-WORLD MEDICARE POPULATION: EARLY RESULTS FROM THE MICRA AV COVERAGE WITH EVIDENCE DEVELOPMENT (CED) STUDY Open
View article: Leadless versus transvenous single‐chamber ventricular pacemakers: 3 year follow‐up of the Micra CED study
Leadless versus transvenous single‐chamber ventricular pacemakers: 3 year follow‐up of the Micra CED study Open
Introduction The Micra Coverage with Evidence Development (CED) Study is a novel comparative analysis of Micra (leadless VVI) and transvenous single‐chamber ventricular pacemakers (transvenous VVI) using administrative claims data. To comp…
View article: Two-year outcomes of leadless vs. transvenous single-chamber ventricular pacemaker in high-risk subgroups
Two-year outcomes of leadless vs. transvenous single-chamber ventricular pacemaker in high-risk subgroups Open
Aims This study compares clinical outcomes between leadless pacemakers (leadless-VVI) and transvenous ventricular pacemakers (transvenous ventricular permanent-VVI) in subgroups of patients at higher risk of pacemaker complications. Method…
View article: Collection of economic data using UB-04s: Is it worth the effort? Evidence from two clinical trials
Collection of economic data using UB-04s: Is it worth the effort? Evidence from two clinical trials Open
Cost collection using UB-04 forms for economic evaluation is challenging, as UB-04 collection is time and effort intensive and compliance is imperfect. Alternative data sources could overcome those challenges. The objective of this study i…
View article: Chronic outcomes of leadless vs transvenous single chamber ventricular pacemakers in high-risk subgroups
Chronic outcomes of leadless vs transvenous single chamber ventricular pacemakers in high-risk subgroups Open
Background The Micra leadless pacemaker (LP-VVI) has been shown to have lower chronic complications and device-related reinterventions compared to transvenous ventricular pacemakers (TV-VVI) in a large, real-world population. This study co…
View article: Diagnostic sensitivity and cost per diagnosis of ambulatory cardiac monitoring strategies in unexplained syncope patients
Diagnostic sensitivity and cost per diagnosis of ambulatory cardiac monitoring strategies in unexplained syncope patients Open
Diagnosing cardiac pauses that could produce syncopal episodes is important to guide appropriate therapy. However, the infrequent nature of these episodes can make detection challenging with conventional monitoring (CM) strategies with sho…
View article: Association of AdaptivCRT Algorithm on Mortality, Healthcare Resource Utilization and Cost in a Real-World Population
Association of AdaptivCRT Algorithm on Mortality, Healthcare Resource Utilization and Cost in a Real-World Population Open
View article: Leadless vs. transvenous single-chamber ventricular pacing in the Micra CED study: 2-year follow-up
Leadless vs. transvenous single-chamber ventricular pacing in the Micra CED study: 2-year follow-up Open
Aims Clinical trials have demonstrated the safety and efficacy of the Micra leadless VVI pacemaker; however, longer-term outcomes in a large, real-world population with a contemporaneous comparison to transvenous VVI pacemakers have not be…
View article: Cost-Effectiveness Analysis of Implantable Cardioverter Defibrillator Therapy for Primary Prevention Patients with Additional Risk Factors in Brazil
Cost-Effectiveness Analysis of Implantable Cardioverter Defibrillator Therapy for Primary Prevention Patients with Additional Risk Factors in Brazil Open
Background: Implantable cardiac defibrillators (ICDs) therapy for primary prevention (PP) of sudden cardiac arrest (SCA) is well-established but underutilized globally. The Improve SCA study has identified a cohort of patients called 1.5 p…
View article: Geographic Competition in Emergency Department Services
Geographic Competition in Emergency Department Services Open
University of Minnesota Ph.D. dissertation. 2021. Major: Health Services Research, Policy and Administration. Advisors: Roger Feldman, Jean Abraham. 1 computer file (PDF); 132 pages.
View article: Physician variation in the de‐adoption of ineffective statin and fibrate therapy
Physician variation in the de‐adoption of ineffective statin and fibrate therapy Open
Objective To describe physicians’ variation in de‐adopting concurrent statin and fibrate therapy for type 2 diabetic patients following a reversal in clinical evidence. Data Sources We analyzed 2007‐2015 claims data from OptumLabs ® Data W…
View article: Comparison of cost-effectiveness of implantable cardioverter defibrillator therapy in patients for primary prevention in Latin America: an analysis using the Improve SCA study
Comparison of cost-effectiveness of implantable cardioverter defibrillator therapy in patients for primary prevention in Latin America: an analysis using the Improve SCA study Open
ICD therapy is cost-effective in Mexico and Uruguay and potentially cost-effective in Colombia for a 1.5PP population. Variability in ICER estimates by country can be explained by differences in non-cardiac deaths and cost inputs.
View article: Implantable cardioverter defibrillator therapy is cost effective for primary prevention patients in Taiwan: An analysis from the Improve SCA trial
Implantable cardioverter defibrillator therapy is cost effective for primary prevention patients in Taiwan: An analysis from the Improve SCA trial Open
Objective Implantable cardiac defibrillators (ICDs) for primary prevention (PP) of sudden cardiac arrest (SCA) are well-established but underutilized globally. The Improve SCA study has identified a cohort of patients called 1.5 primary pr…
View article: Cost comparison of conventional monitoring strategies to diagnose syncope patients with pause arrhythmias relative to insertable cardiac monitoring: a simulation approach
Cost comparison of conventional monitoring strategies to diagnose syncope patients with pause arrhythmias relative to insertable cardiac monitoring: a simulation approach Open
Background The infrequent nature of syncope can make diagnosis of cardiac pauses challenging with conventional monitoring (CM) strategies of intermittent external short-term ECG monitoring. Insertable cardiac monitors (ICMs) continuously m…
View article: Patient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm
Patient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm Open
View article: Improving Patient-Centered Care by Assessing Patient Preferences for Multiple Sclerosis Disease-Modifying Agents: A Stated-Choice Experiment
Improving Patient-Centered Care by Assessing Patient Preferences for Multiple Sclerosis Disease-Modifying Agents: A Stated-Choice Experiment Open
Patient-centered MS therapy using DMAs should include discussion of side effects and relapse risk.
View article: Adherence to Disease-Modifying Therapies for Multiple Sclerosis
Adherence to Disease-Modifying Therapies for Multiple Sclerosis Open
TEVA provided funding for this study and had the option to review the manuscript. The authors retained autonomy in the determination of the final content of this work. Study concept and design were contributed by Carlin, Anderson, and Higu…
View article: The Impact of Narrow Provider Networks on Patterns of Care
The Impact of Narrow Provider Networks on Patterns of Care Open
Background/Aims: Our objective is to determine factors affecting choice of narrow provider network plans, and whether care covered by a narrow network preferred provider organization (PPO) plan differs from care provided in a plan with a b…