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View article: Author Correction: Hypothalamic S1P/S1PR1 axis controls energy homeostasis
Author Correction: Hypothalamic S1P/S1PR1 axis controls energy homeostasis Open
Correction to: Nature Communicationshttps://doi.org/10.1038/ncomms5859, published online 25 September 2014 In the original version of this Article, the Western blot images of Tubulin from the arcuate nucleus and hindbrain and the blots of …
View article: Correction for: Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise
Correction for: Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise Open
Aging | doi:10.18632/aging.103194. Vagner Ramon Rodrigues Silva, Carlos Kiyoshi Katashima, Carla G. Bueno Silva, Luciene Lenhare, Thayana Oliveira Micheletti, Rafael Ludemann Camargo, Ana Carolina Ghezzi, Juliana Alves Camargo, Alexandre M…
View article: Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice
Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice Open
The impairment of the mitochondrial functions is a hallmark of aging. During aging, there is a downregulation of two mechanisms strictly associated with mitochondrial integrity, including the mitonuclear imbalance (eg, imbalance in mitocho…
View article: Effects of ninety minutes per week of continuous aerobic exercise on blood pressure in hypertensive obese humans
Effects of ninety minutes per week of continuous aerobic exercise on blood pressure in hypertensive obese humans Open
The main objective of this study was to examine the effect of continuous aerobic training (CAT) in hypertensive, obese people. Seven patients of average age (45.3±3.9 years), height (1.63±0.1 m), body weight (89.09±22.0 kg), and body mass …
View article: Chronic exercise reduces hypothalamic transforming growth factor-β1 in middle-aged obese mice
Chronic exercise reduces hypothalamic transforming growth factor-β1 in middle-aged obese mice Open
Obesity and aging are associated with hypothalamic inflammation, hyperphagia and abnormalities in the thermogenesis control. It has been demonstrated that the association between aging and obesity induces hypothalamic inflammation and meta…
View article: iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents
iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents Open
Inducible nitric oxide (iNOS)-mediated S-nitrosation of the metabolic signaling pathway has emerged as a post-translational modification that triggers insulin resistance in obesity and aging. However, the effects of S-nitrosation in contro…
View article: Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise
Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise Open
Recently, we demonstrated that the hypothalamic S1PR1/STAT3 axis plays a critical role in the control of food consumption and energy expenditure in rodents. Here, we found that reduction of hypothalamic S1PR1 expression occurs in an age-de…