Lucile Guerber
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View article: UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope
UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope Open
Assembly of macromolecular complexes at correct cellular sites is crucial for cell function. Nuclear pore complexes (NPCs) are large cylindrical assemblies with eightfold rotational symmetry, built through hierarchical binding of nucleopor…
View article: UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope
UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope Open
Assembly of macromolecular complexes at correct cellular sites is crucial for cell function. Nuclear pore complexes (NPCs) are large cylindrical assemblies with eightfold rotational symmetry, built through hierarchical binding of nucleopor…
View article: UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
UBAP2L-dependent coupling of PLK1 localization and stability during mitosis Open
PLK1 is an important regulator of mitosis whose protein levels and activity fluctuate during the cell cycle. PLK1 dynamically localizes to various mitotic structures to regulate chromosome segregation. However, the signaling pathways linki…
View article: Ubiquitin Binding Protein 2-Like (UBAP2L): is it so NICE After All?
Ubiquitin Binding Protein 2-Like (UBAP2L): is it so NICE After All? Open
Ubiquitin Binding Protein 2-like (UBAP2L, also known as NICE-4) is a ubiquitin- and RNA-binding protein, highly conserved in metazoans. Despite its abundance, its functions have only recently started to be characterized. Several studies ha…