Lúcio Ricardo Leite Diniz
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View article: Anti-Inflammatory and Antioxidant Activities of Eugenol: An Update
Anti-Inflammatory and Antioxidant Activities of Eugenol: An Update Open
Medicinal plants are a rich source of bioactive compounds that possess pharmacological properties for preventing and treating inflammation-related diseases. Essential oils is a chemical class that contains many bioactive compounds, such as…
View article: Sustentabilidade na educação: integrando a agroecologia e plantas medicinais nas escolas
Sustentabilidade na educação: integrando a agroecologia e plantas medicinais nas escolas Open
A agroecologia é introduzida como uma ferramenta transformadora da educação, indo além de práticas agrícolas, abrangendo questões sociais, políticas, ambientais e econômicas. A integração da agroecologia e das plantas medicinais nas escola…
View article: <scp>IAPT</scp> chromosome data 39 – Extended version
<span>IAPT</span> chromosome data 39 – Extended version Open
*Address for correspondence: [email protected] Financial support from CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico), CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) and FAPESQ (Fundação de Apoio à…
View article: Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential
Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential Open
An intense effort has been focused on new therapeutic approaches and the development of technologies for more efficient and rapid wound healing. The research for plants used for long time in traditional medicine in the treatment of wound h…
View article: The Essential Oil of Hyptis crenata Inhibits the Increase in Secretion of Inflammatory Mediators
The Essential Oil of Hyptis crenata Inhibits the Increase in Secretion of Inflammatory Mediators Open
Background: Hyptis crenata is a plant of great ethnopharmacological importance widely distributed in South American countries. In Northeast Brazil, teas or infusions of its aerial parts are used in folk medicine to treat several acute and …
View article: Renoprotective Effects of Luteolin: Therapeutic Potential for COVID-19-Associated Acute Kidney Injuries
Renoprotective Effects of Luteolin: Therapeutic Potential for COVID-19-Associated Acute Kidney Injuries Open
Acute kidney injury (AKI) has been increasingly reported in critically-ill COVID-19 patients. Moreover, there was significant positive correlation between COVID-19 deaths and renal disorders in hospitalized COVID-19 patients with underlyin…
View article: Catechins: Therapeutic Perspectives in COVID-19-Associated Acute Kidney Injury
Catechins: Therapeutic Perspectives in COVID-19-Associated Acute Kidney Injury Open
Data obtained from several intensive care units around the world have provided substantial evidence of the strong association between impairment of the renal function and in-hospital deaths of critically ill COVID-19 patients, especially t…
View article: Bioactive Terpenes and Their Derivatives as Potential SARS-CoV-2 Proteases Inhibitors from Molecular Modeling Studies
Bioactive Terpenes and Their Derivatives as Potential SARS-CoV-2 Proteases Inhibitors from Molecular Modeling Studies Open
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus; the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Millions of cases and deaths to date have resulted in a global challenge for healthcare sy…
View article: The essential oil of Hyptis crenata Pohl ex Benth. presents an antiedematogenic effect in mice
The essential oil of Hyptis crenata Pohl ex Benth. presents an antiedematogenic effect in mice Open
Hyptis crenata, commonly known as "salva-do-Marajó", "hortelã-do-campo", and "hortelãzinha", is used in folk medicine in Northeast Brazil as tea or infusion to treat inflammatory diseases. Due to the pharmacological efficacy and the low to…
View article: Mechanistic Aspects and Therapeutic Potential of Quercetin against COVID-19-Associated Acute Kidney Injury
Mechanistic Aspects and Therapeutic Potential of Quercetin against COVID-19-Associated Acute Kidney Injury Open
The inflammatory mediator and oxidant agent storm caused by the SARS-CoV-2 infection has been strongly associated with the failure of vital organs observed in critically ill patients with coronavirus disease 2019 (COVID-19) and the death o…
View article: Natural Antioxidants: A Review of Studies on Human and Animal Coronavirus
Natural Antioxidants: A Review of Studies on Human and Animal Coronavirus Open
The outbreaks of viruses with wide spread and mortality in the world population have motivated the research for new therapeutic approaches. There are several viruses that cause a biochemical imbalance in the infected cell resulting in oxid…
View article: Antidepressant Potential of Cinnamic Acids: Mechanisms of Action and Perspectives in Drug Development
Antidepressant Potential of Cinnamic Acids: Mechanisms of Action and Perspectives in Drug Development Open
Depression is a health problem that compromises the quality of life of the world′s population. It has different levels of severity and a symptomatic profile that affects social life and performance in work activities, as well as a high num…
View article: Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis
Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis Open
Our data showed that the electrophysiologic alterations in peripheral nerves vary with the fiber type and might be identified in the first 24 h of sepsis, before clinical signs of neuromuscular disorders.