Lucrezia Rovati
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View article: The effectiveness of training programmes in reducing short peripheral intravenous catheter failures: A systematic review
The effectiveness of training programmes in reducing short peripheral intravenous catheter failures: A systematic review Open
Structured training programmes can help reduce sPVC failure rates, despite variations in programme implementation. Short- and long-term programmes showed benefits, with long-term training supporting sustained adherence to evidence-based pr…
View article: Effectiveness of a structured triage system in improving timeliness of emergency care in a resource-limited rural hospital in Uganda
Effectiveness of a structured triage system in improving timeliness of emergency care in a resource-limited rural hospital in Uganda Open
View article: Development and validation of a machine learning model for real-time prediction of invasive mechanical ventilation weaning readiness
Development and validation of a machine learning model for real-time prediction of invasive mechanical ventilation weaning readiness Open
View article: Challenges of Ventilator Procurement and Distribution in the ICU During the COVID-19 Pandemic: A Scoping Review
Challenges of Ventilator Procurement and Distribution in the ICU During the COVID-19 Pandemic: A Scoping Review Open
OBJECTIVES: The goal of this scoping review was to review some of the challenges hospitals faced in dealing with the shortage of ventilators during the COVID-19 pandemic and the solutions they were able to implement or suggested. By highli…
View article: Defining the need for analgesia in the emergency department: protocol for an international Delphi process
Defining the need for analgesia in the emergency department: protocol for an international Delphi process Open
Introduction The high prevalence of pain in the emergency department (ED) highlights the importance of accurate assessments to provide effective interventions. However, common pain scales such as the Numerical Pain Rating Scale have shown …
View article: Development of an Emergency Department Safety Checklist through a global consensus process
Development of an Emergency Department Safety Checklist through a global consensus process Open
View article: Model-driven engineering for digital twins: a graph model-based patient simulation application
Model-driven engineering for digital twins: a graph model-based patient simulation application Open
Introduction Digital twins of patients are virtual models that can create a digital patient replica to test clinical interventions in silico without exposing real patients to risk. With the increasing availability of electronic health reco…
View article: Leveraging social media for resident training in developing countries: A case study of Libya
Leveraging social media for resident training in developing countries: A case study of Libya Open
Social media platforms have emerged as invaluable tools for remote training in resource-constrained countries. This study presents the development, implementation, and preliminary assessment of a remote intensive care unit (ICU) training p…
View article: Development and validation of a preliminary multivariable diagnostic model for identifying unusual infections in hospitalized patients
Development and validation of a preliminary multivariable diagnostic model for identifying unusual infections in hospitalized patients Open
Diagnostic delay leads to poor outcomes in infections, and it occurs more often when the causative agent is unusual. Delays are attributable to failing to consider such diagnoses in a timely fashion. Using routinely collected electronic he…
View article: Centralized Multipatient Dashboards' Impact on Intensive Care Unit Clinician Performance and Satisfaction: A Systematic Review
Centralized Multipatient Dashboards' Impact on Intensive Care Unit Clinician Performance and Satisfaction: A Systematic Review Open
Background Intensive care unit (ICU) clinicians encounter frequent challenges with managing vast amounts of fragmented data while caring for multiple critically ill patients simultaneously. This may lead to increased provider cognitive loa…
View article: Development and usability testing of a patient digital twin for critical care education: a mixed methods study
Development and usability testing of a patient digital twin for critical care education: a mixed methods study Open
Background Digital twins are computerized patient replicas that allow clinical interventions testing in silico to minimize preventable patient harm. Our group has developed a novel application software utilizing a digital twin patient mode…
View article: Leveraging Social Media for Critical Care Resident Training in Developing Countries: A Case Study of Libya
Leveraging Social Media for Critical Care Resident Training in Developing Countries: A Case Study of Libya Open
View article: Endoscopic Ultrasound to Identify the Actual Cause of Idiopathic Acute Pancreatitis: A Systematic Review
Endoscopic Ultrasound to Identify the Actual Cause of Idiopathic Acute Pancreatitis: A Systematic Review Open
Idiopathic acute pancreatitis (IAP) presents a diagnostic challenge and refers to cases where the cause of acute pancreatitis remains uncertain despite a comprehensive diagnostic evaluation. Endoscopic ultrasound (EUS) has emerged as a val…
View article: Endoscopic Ultrasound to Identify the Actual Cause of Idiopathic Acute Pancreatitis: A Comprehensive Review
Endoscopic Ultrasound to Identify the Actual Cause of Idiopathic Acute Pancreatitis: A Comprehensive Review Open
Idiopathic acute pancreatitis (IAP) presents a diagnostic challenge and refers to cases where the cause of acute pancreatitis remains uncertain despite a comprehensive diagnostic evalua-tion. Endoscopic ultrasound (EUS) has emerged as a va…
View article: The Diagnostic Accuracy of Metagenomic Next-Generation Sequencing in Diagnosing<i>Pneumocystis</i>Pneumonia: A Systemic Review and Meta-analysis
The Diagnostic Accuracy of Metagenomic Next-Generation Sequencing in Diagnosing<i>Pneumocystis</i>Pneumonia: A Systemic Review and Meta-analysis Open
Background Pneumocystis pneumonia (PCP) is a growing concern as the immunocompromised population expands. Current laboratory approaches are limited. This systematic review aimed to evaluate metagenomic next-generation sequencing (MNGS) tes…
View article: Implementation of a Multimodal Knowledge-Exchange Platform to Provide Trauma Critical Care Education During the Ongoing Conflict in Ukraine
Implementation of a Multimodal Knowledge-Exchange Platform to Provide Trauma Critical Care Education During the Ongoing Conflict in Ukraine Open
Importance The conflict in Ukraine has forced civilian hospitals with limited trauma and battlefield medicine experience to care for casualties of war, placing significant strain on the health care system. Using the Checklist for Early Rec…
View article: Impact of the COVID-19 Pandemic on Urologic Oncology Surgery: Implications for Moving Forward
Impact of the COVID-19 Pandemic on Urologic Oncology Surgery: Implications for Moving Forward Open
The COVID-19 pandemic has caused the destruction of routine hospital services globally, leading to an increase in the backlog of elective surgery cases. The aim of the study was to retrospectively investigate the pandemic’s impact on the u…
View article: <b>Mer tyrosine kinase</b> <b>as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease</b>
<b>Mer tyrosine kinase</b> <b>as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease</b> Open
Objectives IgG4-related disease (IgG4-RD) is a systemic fibro-inflammatory disorder characterized by a dysregulated resolution of inflammation and wound healing response that might develop after an apoptotic insult induced by cytotoxic T l…
View article: AB0154 MERTK AND THE RESOLUTION OF INFLAMMATION IN IGG4-RELATED DISEASE
AB0154 MERTK AND THE RESOLUTION OF INFLAMMATION IN IGG4-RELATED DISEASE Open
View article: B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma
B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma Open
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent stromal reaction that has been variably implicated in both tumor growth and tumor suppression. B-lymphocytes have been recently implicated in PDAC progression but thei…
View article: B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease Open
View article: Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors
Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors Open
Dendritic cells (DCs) initiate adaptive immune responses after their migration to secondary lymphoid organs. The LXR ligands/oxysterols and the RXR ligand 9-cis Retinoic Acid (9-cis RA) were shown to dampen DC migration to lymphoid organs …
View article: Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse
Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse Open
View article: SAT0011 Mertk+ monocytes are expanded in the peripheral blood of patients with active igg4-related disease and infiltrate affected organs
SAT0011 Mertk+ monocytes are expanded in the peripheral blood of patients with active igg4-related disease and infiltrate affected organs Open
View article: THU0035 A cd8 alpha-negative subset of cd4+slamf7+ cytotoxic t cells is expanded in patients with igg4-related disease and decreases following glucocorticoid treatment
THU0035 A cd8 alpha-negative subset of cd4+slamf7+ cytotoxic t cells is expanded in patients with igg4-related disease and decreases following glucocorticoid treatment Open
View article: THU0038 Increase of circulating memory b cells after glucocorticoid-induced remission identifies patients at risk of igg4-related disease relapse
THU0038 Increase of circulating memory b cells after glucocorticoid-induced remission identifies patients at risk of igg4-related disease relapse Open
View article: A <scp>CD</scp>8α− Subset of <scp>CD</scp>4+<scp>SLAMF</scp>7+ Cytotoxic T Cells Is Expanded in Patients With IgG4‐Related Disease and Decreases Following Glucocorticoid Treatment
A <span>CD</span>8α− Subset of <span>CD</span>4+<span>SLAMF</span>7+ Cytotoxic T Cells Is Expanded in Patients With IgG4‐Related Disease and Decreases Following Glucocorticoid Treatment Open
Objective An unconventional population of CD 4+ signaling lymphocytic activation molecule family member 7–positive ( SLAMF 7+) cytotoxic effector memory T ( T EM ) cells ( CD 4+ cytotoxic T lymphocytes [ CTL s]) has been linked causally to…
View article: AB0985 Methotrexate as induction of remission therapy for localized manifestations of IGG4-related disease
AB0985 Methotrexate as induction of remission therapy for localized manifestations of IGG4-related disease Open