Lucy Grigoroff
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View article: Evaluation of imputation strategies for multi-centre studies: Application to a large clinical pathology dataset
Evaluation of imputation strategies for multi-centre studies: Application to a large clinical pathology dataset Open
As part of a strategy for accommodating missing data in large heterogeneous datasets, two Random Forest-based (RF) imputation methods, missForest and MICE were evaluated along with several strategies to help navigate the inherently incompl…
View article: A clinical chemical atlas of xenobiotic toxicity for the Sprague–Dawley rat
A clinical chemical atlas of xenobiotic toxicity for the Sprague–Dawley rat Open
The Consortium for Metabonomic Toxicology (COMET) studies was designed to model metabolic responses to organ- and mechanism-specific toxins to predict acute drug toxicity in rats. A range of clinical chemical parameters were measured in 7-…
View article: Evaluation of imputation strategies for multi-centre studies: Application to a large clinical pathology dataset
Evaluation of imputation strategies for multi-centre studies: Application to a large clinical pathology dataset Open
As part of a strategy for accommodating missing data in large heterogeneous datasets, two Random Forest-based (RF) imputation methods, missForest and MICE were evaluated along with several strategies to help them handle the inherent struct…