Lucy Vass
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View article: Novel characterisation of dairy herds in Wales: A description of principal herd typologies and antimicrobial use patterns
Novel characterisation of dairy herds in Wales: A description of principal herd typologies and antimicrobial use patterns Open
Antimicrobial resistance (AMR) is one of the top global public health concerns. Reducing and refining antimicrobial use (AMU) in farmed livestock is vital in slowing the development of AMR and preserving the efficacy of antimicrobials (AMs…
View article: Novel characterisation of sheep flocks in Wales: A description of principal flock typologies and antimicrobial use patterns
Novel characterisation of sheep flocks in Wales: A description of principal flock typologies and antimicrobial use patterns Open
There is increasing pressure to reduce and refine antimicrobial use (AMU) in farmed livestock, to slow the development of antimicrobial resistance (AMR) and preserve the efficacy of antimicrobials (AMs) in both humans and animals. Developi…
View article: Genomic epidemiology of third-generation cephalosporin-resistant <i>Escherichia coli</i> from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms
Genomic epidemiology of third-generation cephalosporin-resistant <i>Escherichia coli</i> from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms Open
Little is known about the ecology of critically important antibiotic resistance among bacteria with the potential to be opportunistic human pathogens (e.g., Escherichia coli ) on South American farms. By studying 70 pig and dairy cattle fa…
View article: Novel Characterisation of Dairy Herds in Wales: A Description of Principal Herd Typologies and Antimicrobial Use Patterns
Novel Characterisation of Dairy Herds in Wales: A Description of Principal Herd Typologies and Antimicrobial Use Patterns Open
View article: Genomic epidemiology of third-generation cephalosporin-resistant<i>Escherichia coli</i>from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms
Genomic epidemiology of third-generation cephalosporin-resistant<i>Escherichia coli</i>from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms Open
Control measures are being introduced globally to reduce the prevalence of antibiotic resistant (ABR) bacteria on farms. However, little is known about the current prevalence and molecular ecology of ABR in key opportunistic human pathogen…
View article: Novel Characterisation of Sheep Flocks in Wales: A Description of Principal Flock Typologies and Antimicrobial Use Patterns
Novel Characterisation of Sheep Flocks in Wales: A Description of Principal Flock Typologies and Antimicrobial Use Patterns Open
View article: One Health drivers of antibacterial resistance: Quantifying the relative impacts of human, animal and environmental use and transmission
One Health drivers of antibacterial resistance: Quantifying the relative impacts of human, animal and environmental use and transmission Open
Our model provides a simple framework to explain the mechanisms underpinning ABR, suggesting that future interventions targeting the simultaneous reduction of transmission and ABU would help to control ABR more effectively in Thailand.
View article: Reduced Antibacterial Drug Resistance and <i>bla</i> <sub>CTX-M</sub> β-Lactamase Gene Carriage in Cattle-Associated Escherichia coli at Low Temperatures, at Sites Dominated by Older Animals, and on Pastureland: Implications for Surveillance
Reduced Antibacterial Drug Resistance and <i>bla</i> <sub>CTX-M</sub> β-Lactamase Gene Carriage in Cattle-Associated Escherichia coli at Low Temperatures, at Sites Dominated by Older Animals, and on Pastureland: Implications for Surveillance Open
Antibacterial resistance poses a significant threat to human and animal health and global food security. Surveillance for resistance on farms is important for many reasons, including tracking impacts of interventions aimed at reducing the …
View article: Estimating the COVID-19 epidemic trajectory and hospital capacity requirements in South West England: a mathematical modelling framework
Estimating the COVID-19 epidemic trajectory and hospital capacity requirements in South West England: a mathematical modelling framework Open
Objectives To develop a regional model of COVID-19 dynamics for use in estimating the number of infections, deaths and required acute and intensive care (IC) beds using the South West England (SW) as an example case. Design Open-source age…
View article: Estimating the COVID-19 epidemic trajectory and hospital capacity requirements in South West England: a mathematical modelling framework
Estimating the COVID-19 epidemic trajectory and hospital capacity requirements in South West England: a mathematical modelling framework Open
Objectives To develop a regional model of COVID-19 dynamics, for use in estimating the number of infections, deaths and required acute and intensive care (IC) beds using the South West of England (SW) as an example case. Design Open-source…
View article: One Health drivers of antibacterial resistance: quantifying the relative impacts of human, animal and environmental use and transmission
One Health drivers of antibacterial resistance: quantifying the relative impacts of human, animal and environmental use and transmission Open
Introduction Antimicrobial resistance (AMR), particularly antibacterial resistance (ABR) is a major global health security threat projected to cause over ten million human deaths annually by 2050. There is a disproportionate burden of ABR …
View article: Reduced antibacterial drug resistance and <i>bla</i><sub>CTX-M</sub> β-lactamase gene carriage in cattle-associated <i>Escherichia coli</i> at low temperatures, at sites dominated by older animals and on pastureland: implications for surveillance
Reduced antibacterial drug resistance and <i>bla</i><sub>CTX-M</sub> β-lactamase gene carriage in cattle-associated <i>Escherichia coli</i> at low temperatures, at sites dominated by older animals and on pastureland: implications for surveillance Open
Little is known about the drivers of critically important antibacterial resistance in species with zoonotic potential present on farms (e.g. CTX-M □-lactamase-positive Escherichia coli ). Here, we collected samples, monthly over a two-year…
View article: Flux sampling is a powerful tool to study metabolism under changing environmental conditions
Flux sampling is a powerful tool to study metabolism under changing environmental conditions Open
The development of high-throughput ‘omic techniques has sparked a rising interest in genome-scale metabolic models, with applications ranging from disease diagnostics to crop adaptation. Efficient and accurate methods are required to analy…