Luda Yan
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View article: Study on the Central Neural Pathways Connecting the Brain and Peripheral Acupoints Using Neural Tracers
Study on the Central Neural Pathways Connecting the Brain and Peripheral Acupoints Using Neural Tracers Open
Background Acupuncture is widely used for therapeutic purposes, but the neural mechanisms underlying its effects are not fully understood. This study aims to investigate the neural projections from acupoints and subcutaneous (sham acupoint…
View article: A surface-based cross-sectional fMRI study on brain function differences between comorbid mild or moderate depression and insomnia
A surface-based cross-sectional fMRI study on brain function differences between comorbid mild or moderate depression and insomnia Open
Background The mechanisms of Comorbid mild or moderate depression and insomnia (CmiDaI or CmoDaI) are complex, and stratification remains poorly understood. Methods Resting-state fMRI data were collected from 32 patients with CmiDaI, 32 wi…
View article: Gray matter and cognitive alteration related to chronic obstructive pulmonary disease patients: combining ALE meta-analysis and MACM analysis
Gray matter and cognitive alteration related to chronic obstructive pulmonary disease patients: combining ALE meta-analysis and MACM analysis Open
Chronic obstructive pulmonary disease (COPD) is frequently comorbid with cognitive impairment, but it has not been paid enough attention, and its neuroanatomical characteristics have not been fully identified. Voxel-based morphometric (VBM…
View article: Fire acupuncture for plaque psoriasis case series
Fire acupuncture for plaque psoriasis case series Open
Objective: To investigate the clinical efficacy of fire acupuncture (FA) on plaque psoriasis (PP), exploring its suitable syndrome types, in order to achieve better therapeutic effects, accelerate the possibility of psoriasis skin lesion r…
View article: Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling
Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling Open
EA significantly mitigated the symptom of depression in mice, which was closely associated with the repressed neuroinflammation, increased monoamine concentration, inactivated microglia, and inhibited cGAS-STING-NLRP3 signaling.
View article: Acupuncture for generalized anxiety disorder: a study protocol for a randomized controlled trial
Acupuncture for generalized anxiety disorder: a study protocol for a randomized controlled trial Open
During the COVID-19 outbreak, there was a sharp increase in generalized anxiety disorder (GAD). Acupuncture therapy has the advantages of accurate clinical efficacy, safety and reliability, few adverse reactions, and no dependence, and is …
View article: Effects of Horticultural Therapy Combined with Intradermal Needle Therapy on Generalised Anxiety, Cortical Excitability and HPA-related Hormones in an Isolated Population during the COVID-19 Pandemic: Protocol for a Randomised Controlled Clinical Trial
Effects of Horticultural Therapy Combined with Intradermal Needle Therapy on Generalised Anxiety, Cortical Excitability and HPA-related Hormones in an Isolated Population during the COVID-19 Pandemic: Protocol for a Randomised Controlled Clinical Trial Open
Introduction: Coronavirus disease 2019 (COVID-19) is a novel, highly infectious disease that is a severe danger to human life and has spawned a worldwide public health emergency. Most countries have implemented measures of isolation to pre…
View article: Gray Matter and Cognitive Alteration Related to Chronic Obstructive Pulmonary Disease Patients: Combining ALE Meta-analysis and MACM Analysis
Gray Matter and Cognitive Alteration Related to Chronic Obstructive Pulmonary Disease Patients: Combining ALE Meta-analysis and MACM Analysis Open
Background: Chronic obstructive pulmonary disease (COPD) is frequently comorbid with cognitive impairment, but it has not been paid enough attention, and its neuroanatomical characteristics have not been fully identified. Methods: Voxel-ba…
View article: Prognostic role of multiple abnormal genes in non-small-cell lung cancer
Prognostic role of multiple abnormal genes in non-small-cell lung cancer Open
Co-occurring mutation or overexpression of different genes has different effects on the overall survival and prognosis of NSCLC patients. Combined with TKI treatment, the co-occurring mutation of some genes may have a synergistic effect on…
View article: Efficacy of the Integrative Acupuncture and Moxibustion Treatment in Patients With Major Depressive Disorder: The Study Protocol for a Multicenter, Single-Blinded, Randomized Trial in China
Efficacy of the Integrative Acupuncture and Moxibustion Treatment in Patients With Major Depressive Disorder: The Study Protocol for a Multicenter, Single-Blinded, Randomized Trial in China Open
Introduction Antidepressants are the front-line treatments for major depressive disorder (MDD), but remain unsatisfactory in outcome. An increasing number of patients are interested in acupuncture and moxibustion treatment as complementary…
View article: Acupuncture treatment of hypertension with insomnia: A protocol for randomized, double-blind, placebo controlled trial research.
Acupuncture treatment of hypertension with insomnia: A protocol for randomized, double-blind, placebo controlled trial research. Open
This study is a randomized, double-blind (patients and evaluators), and placebo-controlled clinical trial to investigate the effect of acupuncture in hypertension patients' insomnia management. We will recruit 158 hypertension patients suf…
View article: The Role of Acupuncture in Hormonal Shock-Induced Cognitive-Related Symptoms in Perimenopausal Depression: A Randomized Clinical Controlled Trial
The Role of Acupuncture in Hormonal Shock-Induced Cognitive-Related Symptoms in Perimenopausal Depression: A Randomized Clinical Controlled Trial Open
Introduction: Perimenopausal depression is predominantly caused by hormone shock, but the underlying physical and psychological factors are still unclear. Objectives: To explore the constituent components of perimenopausal depression by dy…
View article: Implementation and Evaluation of the Integrated Acupuncture and Moxibustion Treatment (Acupuncture, Moxibustion and Auricular Acupuncture) for Major Depressive Disorder: A Trial Protocol for a Randomized Clinical Trial
Implementation and Evaluation of the Integrated Acupuncture and Moxibustion Treatment (Acupuncture, Moxibustion and Auricular Acupuncture) for Major Depressive Disorder: A Trial Protocol for a Randomized Clinical Trial Open
Background: Because of inadequate psychotherapy resources, antidepressants are the front-line option for Major depressive disorder, but with dissatisfied curative effect. Many patients have an interest in acupuncture and moxibustion treatm…
View article: Intradermal Thumbtack Needle Alleviates Depressive Symptoms and Resets Executive Control System Function in Young Patients With Subthreshold Depression: A Study Protocol of a Randomized, Controlled, and Single-Blind Trial {1}
Intradermal Thumbtack Needle Alleviates Depressive Symptoms and Resets Executive Control System Function in Young Patients With Subthreshold Depression: A Study Protocol of a Randomized, Controlled, and Single-Blind Trial {1} Open
Background: Subthreshold depression is the prodromal stage of a depressive episode, which is characterized by depressive symptoms but fails to meet the diagnostic criteria for depression. At present, there is no recognized therapy for subt…