Ludovic Boytard
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View article: Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City region
Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City region Open
Effective public response to a pandemic relies upon accurate measurement of the extent and dynamics of an outbreak. Viral genome sequencing has emerged as a powerful approach to link seemingly unrelated cases, and large-scale sequencing su…
View article: Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City Region
Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City Region Open
Effective public response to a pandemic relies upon accurate measurement of the extent and dynamics of an outbreak. Viral genome sequencing has emerged as a powerful approach to link seemingly unrelated cases, and large-scale sequencing su…
View article: Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity
Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity Open
During obesity, macrophages infiltrate the visceral adipose tissue and promote inflammation that contributes to type II diabetes. Evidence suggests that the rewiring of cellular metabolism can regulate macrophage function. However, the met…
View article: Let-7f: A New Potential Circulating Biomarker Identified by miRNA Profiling of Cells Isolated from Human Abdominal Aortic Aneurysm
Let-7f: A New Potential Circulating Biomarker Identified by miRNA Profiling of Cells Isolated from Human Abdominal Aortic Aneurysm Open
Abdominal aortic aneurysm (AAA) is a progressive vascular disease responsible for 1–4% of the deaths in elderly men. This study aimed to characterize specific microRNA (miRNA) expression in aneurysmal smooth muscle cells (SMCs) and macroph…
View article: Mapping Semaphorins and Netrins in the Pathogenesis of Human Thoracic Aortic Aneurysms
Mapping Semaphorins and Netrins in the Pathogenesis of Human Thoracic Aortic Aneurysms Open
Thoracic aortic aneurysm (TAA) is a complex life-threatening disease characterized by extensive extracellular matrix (ECM) fragmentation and persistent inflammation, culminating in a weakened aorta. Although evidence suggests defective can…