Ludovico Migliaccio
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View article: Affordable method for channel geometry–specific flow control in microfluidics without commercial pumps
Affordable method for channel geometry–specific flow control in microfluidics without commercial pumps Open
Microfluidic experiments often require precise flow control, but commercial pumps and pressure regulators are costly and can limit accessibility. We introduce a calibration-based strategy that links channel geometry with predictable relati…
View article: Low-dimensional controllability of brain networks
Low-dimensional controllability of brain networks Open
Identifying the driver nodes of a network has crucial implications in biological systems from unveiling causal interactions to informing effective intervention strategies. Despite recent advances in network control theory, results remain i…
View article: Ultrathin Indium Tin Oxide Accumulation Mode Electrolyte‐Gated Transistors for Bioelectronics
Ultrathin Indium Tin Oxide Accumulation Mode Electrolyte‐Gated Transistors for Bioelectronics Open
Electrolyte‐gated field effect transistors and electrochemical transistors have emerged as powerful components for bioelectronic sensors and biopotential recording devices. A set of parameters must be considered when developing devices to …
View article: Influence of Process Parameters on Properties of Non-Reactive RF Magnetron-Sputtered Indium Tin Oxide Thin Films Used as Electrodes for Organic Light-Emitting Diodes
Influence of Process Parameters on Properties of Non-Reactive RF Magnetron-Sputtered Indium Tin Oxide Thin Films Used as Electrodes for Organic Light-Emitting Diodes Open
Indium tin oxide (ITO) is a transparent conductive oxide (TCO) commonly used in the realization of optoelectronic devices needing at least a transparent electrode. In this work, ITO thin films were deposited on glass substrates by non-reac…
View article: Shedding Light on Cardiac Excitation: In Vitro and In Silico Analysis of Native Ca<sup>2+</sup> Channel Activation in Guinea Pig Cardiomyocytes Using Organic Photovoltaic Devices
Shedding Light on Cardiac Excitation: In Vitro and In Silico Analysis of Native Ca<sup>2+</sup> Channel Activation in Guinea Pig Cardiomyocytes Using Organic Photovoltaic Devices Open
Treating cardiac conduction disorders by minimal-invasive means without genetic modifications could advance therapeutic approaches increasing patients' quality of life compared with conventional methods employing electronic devices.
View article: Low-dimensional controllability of brain networks
Low-dimensional controllability of brain networks Open
Network controllability is a powerful tool to study causal relationships in complex systems and identify the driver nodes for steering the network dynamics into desired states. However, due to ill-posed conditions, results become unreliabl…
View article: Photo‐Chemical Stimulation of Neurons with Organic Semiconductors (Adv. Sci. 31/2023)
Photo‐Chemical Stimulation of Neurons with Organic Semiconductors (Adv. Sci. 31/2023) Open
Organic Bioelectronic Highly photosensitive, organic p‐n junctions stimulate primary neurons when illuminated with low‐intensity light via photochemical reactions. The electrophysiology of primary neurons can be influenced by photochemical…
View article: Photo‐Chemical Stimulation of Neurons with Organic Semiconductors
Photo‐Chemical Stimulation of Neurons with Organic Semiconductors Open
Recent advances in light‐responsive materials enabled the development of devices that can wirelessly activate tissue with light. Here it is shown that solution‐processed organic heterojunctions can stimulate the activity of primary neurons…
View article: Downsizing the Channel Length of Vertical Organic Electrochemical Transistors
Downsizing the Channel Length of Vertical Organic Electrochemical Transistors Open
Organic electrochemical transistors (OECTs) are promising building blocks for bioelectronic devices such as sensors and neural interfaces. While the majority of OECTs use simple planar geometry, there is interest in exploring how these dev…
View article: High‐Conductivity Stoichiometric Titanium Nitride for Bioelectronics
High‐Conductivity Stoichiometric Titanium Nitride for Bioelectronics Open
Bioelectronic devices such as neural stimulation and recording devices require stable low‐impedance electrode interfaces. Various forms of nitridated titanium are used in biointerface applications due to robustness and biological inertness…
View article: Laser‐Driven Wireless Deep Brain Stimulation using Temporal Interference and Organic Electrolytic Photocapacitors
Laser‐Driven Wireless Deep Brain Stimulation using Temporal Interference and Organic Electrolytic Photocapacitors Open
Deep brain stimulation (DBS) is a technique commonly used both in clinical and fundamental neurosciences. Classically, brain stimulation requires an implanted and wired electrode system to deliver stimulation directly to the target area. A…
View article: Direct measurement of oxygen reduction reactions at neurostimulation electrodes
Direct measurement of oxygen reduction reactions at neurostimulation electrodes Open
Objective . Electric stimulation delivered by implantable electrodes is a key component of neural engineering. While factors affecting long-term stability, safety, and biocompatibility are a topic of continuous investigation, a widely-acce…
View article: Micropyramid structured photo capacitive interfaces
Micropyramid structured photo capacitive interfaces Open
Optically driven electronic neuromodulation devices are a novel tool in basic research and offer new prospects in medical therapeutic applications. Optimal operation of such devices requires efficient light capture and charge generation, e…
View article: Ultrathin Paper Microsupercapacitors for Electronic Skin Applications
Ultrathin Paper Microsupercapacitors for Electronic Skin Applications Open
Ultrathin devices are rapidly developing for skin‐compatible medical applications and wearable electronics. Powering skin‐interfaced electronics requires thin and lightweight energy storage devices, where solution‐processing enables scalab…
View article: Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex
Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex Open
Objective. For decades electrical stimulation has been used in neuroscience to investigate brain networks and been deployed clinically as a mode of therapy. Classically, all methods of electrical stimulation require implanted electrodes to…
View article: Laser-driven Wireless Deep Brain Stimulation using Temporal Interference and Organic Electrolytic Photocapacitors
Laser-driven Wireless Deep Brain Stimulation using Temporal Interference and Organic Electrolytic Photocapacitors Open
Deep brain stimulation (DBS) is a technique commonly used both in clinical and fundamental neurosciences. Classically, brain stimulation requires an implanted and wired electrode system to deliver stimulation directly to the target area. A…
View article: Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex
Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex Open
Objective For decades electrical stimulation has been used in neuroscience to investigate brain networks and been deployed clinically as a mode of therapy. Classically, all methods of electrical stimulation require implanted electrodes to …
View article: A chronic photocapacitor implant for noninvasive neurostimulation with deep red light
A chronic photocapacitor implant for noninvasive neurostimulation with deep red light Open
Implantable clinical neuroelectronic devices are limited by a lack of reliable, safe, and minimally invasive methods to wirelessly modulate neural tissue. Here, we address this challenge by using organic electrolytic photocapacitors (OEPCs…
View article: Eumelanin Precursor 2-Carboxy-5,6-Dihydroxyindole (DHICA) as Doping Factor in Ternary (PEDOT:PSS/Eumelanin) Thin Films for Conductivity Enhancement
Eumelanin Precursor 2-Carboxy-5,6-Dihydroxyindole (DHICA) as Doping Factor in Ternary (PEDOT:PSS/Eumelanin) Thin Films for Conductivity Enhancement Open
The integration of the pristine not-doped commercial poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) PH1000 with eumelanin, the brown to black kind of melanin pigment, was achieved by dissolving the melanogenic precurso…
View article: Untangling Photofaradaic and Photocapacitive Effects in Organic Optoelectronic Stimulation Devices
Untangling Photofaradaic and Photocapacitive Effects in Organic Optoelectronic Stimulation Devices Open
Light, as a versatile and non-invasive means to elicit a physiological response, offers solutions to problems in basic research as well as in biomedical technologies. The complexity and limitations of optogenetic methods motivate research …
View article: Extracellular Photovoltage Clamp Using Conducting Polymer‐Modified Organic Photocapacitors
Extracellular Photovoltage Clamp Using Conducting Polymer‐Modified Organic Photocapacitors Open
Optoelectronic control of physiological processes accounts for new possibilities ranging from fundamental research to treatment of disease. Among nongenetic light‐driven approaches, organic semiconductor‐based device platforms such as the …
View article: Tuning photoelectrochemical performance of poly(3-hexylthiophene) electrodes <i>via</i> surface structuring
Tuning photoelectrochemical performance of poly(3-hexylthiophene) electrodes <i>via</i> surface structuring Open
The aqueous faradaic and capacitive properties of an organic semiconductor photocathode are finely tuned by via microstructure and wettability.
View article: Evidence of Unprecedented High Electronic Conductivity in Mammalian Pigment Based Eumelanin Thin Films After Thermal Annealing in Vacuum
Evidence of Unprecedented High Electronic Conductivity in Mammalian Pigment Based Eumelanin Thin Films After Thermal Annealing in Vacuum Open
Melanin denotes a variety of mammalian pigments, including the dark electrically conductive eumelanin and the reddish, sulfur-containing, pheomelanin. Organic (bio)electronics is showing increasing interests in eumelanin exploitation, e.g.…
View article: Eumelanin Coating of Silica Aerogel by Supercritical Carbon Dioxide Deposition of a 5,6-Dihydroxyindole Thin Film
Eumelanin Coating of Silica Aerogel by Supercritical Carbon Dioxide Deposition of a 5,6-Dihydroxyindole Thin Film Open
Eumelanin integration in silica aerogel (SA) was achieved via supercritical adsorption of 5,6-dyhydroxyindole (DHI) from CO2. Notably, after the supercritical treatment, DHI evolved towards spontaneous polymerization, which resulted in uni…
View article: Aqueous photo(electro)catalysis with eumelanin thin films
Aqueous photo(electro)catalysis with eumelanin thin films Open
The ubiquitous biopigment eumelanin can function as a photocatalytic and photofaradaic material.
View article: A Study Concerning the Electronic Conductivity in Eumelanin Thin Films
A Study Concerning the Electronic Conductivity in Eumelanin Thin Films Open
This work presents conclusive observations about the long lasting topic of eumelanins' electronic vs. ionic conduction, allowing to access unprecedented conductivity of this mammal pigment. Key strengths of the study include, the easy eume…