Lufuno Malala
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View article: Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa: A mixed-methods study
Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa: A mixed-methods study Open
For clients on HIV treatment in sub-Saharan Africa, early disengagement from care is a critical obstacle to achieving UNAIDS’s second 95 target. While South Africa’s Differentiated Service Delivery Guideline on Fast Track Initiation and Co…
View article: Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa
Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa Open
Despite advances in antiretroviral therapy (ART), a notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4 < 200 cells/µL or WHO stage 3/4. This group experiences higher mort…
View article: Evaluating the impact of differentiated service delivery (DSD) on retention in care and HIV viral suppression in South Africa: A target trial emulation using routine healthcare data
Evaluating the impact of differentiated service delivery (DSD) on retention in care and HIV viral suppression in South Africa: A target trial emulation using routine healthcare data Open
Background Replacing conventional, facility-based HIV treatment with less intensive differentiated service delivery (DSD) models could benefit DSD clients and the health system, but its value depends on maintaining or improving clinical ou…
View article: Client preferences for service delivery during the early treatment period in South Africa and Zambia: Mixed-method findings from a discrete choice experiment and concurrent focus group discussions
Client preferences for service delivery during the early treatment period in South Africa and Zambia: Mixed-method findings from a discrete choice experiment and concurrent focus group discussions Open
Background Disengagement from antiretroviral therapy (ART) is common in the first 6 months of HIV treatment in sub-Saharan Africa. Using mixed-methods we aimed to understand preferences during this early treatment period. Methods Between 8…
View article: Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure
Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure Open
Background The era of universal treatment for HIV has seen high rates of disengagement from antiretroviral therapy (ART) programs and re-engagement after interruptions, with modeled estimates of non-naïve initiators > 50% in many places. M…
View article: Primary healthcare providers’ perspectives on six-month dispensing of antiretroviral therapy (ART) in South Africa: cross-sectional survey of views and preferences
Primary healthcare providers’ perspectives on six-month dispensing of antiretroviral therapy (ART) in South Africa: cross-sectional survey of views and preferences Open
Most healthcare providers at primary healthcare clinics in South Africa are in favour of allowing 6-month dispensing and 12-month prescriptions as options for established ART clients.
View article: Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa
Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa Open
Introduction Despite advances in antiretroviral therapy (ART), notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4 counts <200cells/µL or WHO stage 3/4 conditions. This gr…
View article: Primary healthcare providers’ perspectives on six-month dispensing of HIV medication in South Africa: a cross-sectional survey
Primary healthcare providers’ perspectives on six-month dispensing of HIV medication in South Africa: a cross-sectional survey Open
Background In many African countries the dispensing duration for antiretroviral therapy (ART) medication for HIV treatment has increased from 3 months to 6 months for stable clients. To help inform a decision about whether to move from thr…
View article: Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa: a mixed-methods study
Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa: a mixed-methods study Open
Introduction For clients on HIV treatment in sub-Saharan Africa, disengagement from HIV care in the early treatment period is a critical obstacle to achieving UNAIDS’s second 95 target. While South Africa’s Differentiated Service Delivery …
View article: The impact of differentiated service delivery (DSD) on retention in care and viral suppression in South Africa: A target trial emulation of routine care data
The impact of differentiated service delivery (DSD) on retention in care and viral suppression in South Africa: A target trial emulation of routine care data Open
Introduction Replacing conventional, facility-based HIV treatment with less intensive differentiated service delivery (DSD) models could benefit DSD clients and the health system, but its value depends on maintaining or improving clinical …
View article: Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure
Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure Open
Background The era of universal treatment for HIV has seen high rates of disengagement from antiretroviral therapy (ART) programs and re-engagement after interruptions, with modeled estimates of non-naive initiators >50% in many places. Mo…
View article: Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in South Africa: A retrospective cohort analysis using routinely collected data
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in South Africa: A retrospective cohort analysis using routinely collected data Open
Retention on antiretroviral therapy (ART) during the early treatment period is one of the most serious challenges facing HIV programs, but the timing and patterns of early disengagement from care remain poorly understood. We describe patte…