Luigi Mazzone
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View article: Application of Concomitant Transcranial Direct Current Stimulation (tDCS) and Cognitive Behavioral-Oriented Training (CBT) for Pragmatic Skills Improvement in Young Adults with Autism Spectrum Disorder (ASD): Preliminary Data from a Pilot Study
Application of Concomitant Transcranial Direct Current Stimulation (tDCS) and Cognitive Behavioral-Oriented Training (CBT) for Pragmatic Skills Improvement in Young Adults with Autism Spectrum Disorder (ASD): Preliminary Data from a Pilot Study Open
Objectives: Individuals with Autism Spectrum Disorder (ASD) exhibit difficulties in the social use of language, regardless of age, cognitive abilities, and symptom severity. The left Broca’s area and adjacent cortex are crucial for socio-p…
View article: Restless legs syndrome and growing pains in childhood: understanding the link
Restless legs syndrome and growing pains in childhood: understanding the link Open
Introduction Restless Legs Syndrome (RLS), known as Willis–Ekbom disease, is a common neurological condition that often goes undiagnosed, especially in children. Characterized by an irresistible urge to move the legs, it is typically more …
View article: Clinical Variability of Pediatric MERS: Insights from a Retrospective Observational Study
Clinical Variability of Pediatric MERS: Insights from a Retrospective Observational Study Open
Background/Objectives: Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) is a rare neurological disorder primarily affecting pediatric patients but also observed in adults. The radiological hallmark of MERS is a rever…
View article: Sleep Disorders in a Sample of Patients with Pediatric-Onset Multiple Sclerosis: Focus on Restless Legs Syndrome
Sleep Disorders in a Sample of Patients with Pediatric-Onset Multiple Sclerosis: Focus on Restless Legs Syndrome Open
Background/Objectives: Sleep disorders (SDs) and Restless Legs Syndrome (RLS) have been reported with high prevalence in Multiple Sclerosis (MS), but data on Pediatric-Onset MS (POMS) are scarce. This study aims to assess the prevalence of…
View article: Oxidative stress response and NRF2 signaling pathway in autism spectrum disorder
Oxidative stress response and NRF2 signaling pathway in autism spectrum disorder Open
The prevalence of autism spectrum disorder (ASD), a neurodevelopmental disorder characterized by impairments in social communication and restricted/repetitive behavioral patterns, has increased significantly over the past few decades. The …
View article: Investigating the attenuated psychosis syndrome in youth with autism spectrum disorder: results from an observational study
Investigating the attenuated psychosis syndrome in youth with autism spectrum disorder: results from an observational study Open
Introduction Despite evidence suggesting increased rates of psychosis in individuals with autism spectrum disorder (ASD), the detection of prodromal psychotic symptoms, including attenuated psychosis syndrome (APS), remains underexplored i…
View article: Diagnosing migraine in children and adolescence using ID migraine: results of an Italian multicenter validation
Diagnosing migraine in children and adolescence using ID migraine: results of an Italian multicenter validation Open
Background Since migraine is the most frequent neurological condition, an early diagnosis is important to limit the impact of the disease on the quality of life. Although migraine diagnosis is based on the International Classification of H…
View article: Autism spectrum disorder and 3p24.3p23 triplication: a case report
Autism spectrum disorder and 3p24.3p23 triplication: a case report Open
View article: Prenatal mTOR Inhibitors in Tuberous Sclerosis Complex: Current Insights and Future Directions
Prenatal mTOR Inhibitors in Tuberous Sclerosis Complex: Current Insights and Future Directions Open
Background: Tuberous sclerosis complex (TSC) can present prenatally, often with cardiac rhabdomyomas, which, if large, may cause complications such as hydrops fetalis and reduced cardiac output. Prenatal treatment of these lesions with mTO…
View article: ID-Migraine test for pediatric population: preliminary results from the Italian validation
ID-Migraine test for pediatric population: preliminary results from the Italian validation Open
Background: Migraine is a frequent neurological condition with a high impact on quality life. The diagnosis is clinical in accordance with the International Classification of Headache Disorders version 3 criteria. Early diagnosis is import…
View article: Unsatisfactory response to acute medications does not affect the medication overuse headache development in pediatric chronic migraine
Unsatisfactory response to acute medications does not affect the medication overuse headache development in pediatric chronic migraine Open
View article: Unsatisfactory Response to Acute Medications Does Not Affect the Medication Overuse Headache Development in Pediatric Chronic Migraine
Unsatisfactory Response to Acute Medications Does Not Affect the Medication Overuse Headache Development in Pediatric Chronic Migraine Open
Background: Chronic migraine (CM) affects 2 to 4% of paediatric patients and has a significant impact on their quality of life. While in adults CM is very often associated to medication overuse headache (MOH), in children MOH prevalence is…
View article: Sleep disturbances and behavioral symptoms in pediatric Sotos syndrome
Sleep disturbances and behavioral symptoms in pediatric Sotos syndrome Open
Background Sotos syndrome (SoS) is a rare overgrowth genetic disease caused by intragenic mutations or microdeletions of the NSD1 gene located on chromosome 5q35. SoS population might present cognitive impairment and a spectrum of behavior…
View article: Primary Headaches and Sleep Disorders: Review of Literature about Comorbidity in Children and Adolescents
Primary Headaches and Sleep Disorders: Review of Literature about Comorbidity in Children and Adolescents Open
Sleep disorders and primary headaches are frequent health problems in childhood, and they are often comorbid in an individual, linked by a mutual and complex relationship. This comorbidity is frequent and well documented, but the available…
View article: Internet addiction and gaming disorder in autism spectrum disorder: examining prevalence, socio-demographic factors, and sleep quality in youths
Internet addiction and gaming disorder in autism spectrum disorder: examining prevalence, socio-demographic factors, and sleep quality in youths Open
View article: Clinical, Sociodemographic, and Psychological Factors Associated with Transition Readiness in Patients with Epilepsy
Clinical, Sociodemographic, and Psychological Factors Associated with Transition Readiness in Patients with Epilepsy Open
Background: The transition to adult care for patients with epilepsy is a complicated clinical issue associated with adverse outcomes, including non-adherence to treatment, dropout of medical care, and worse prognosis. Moreover, youngsters …
View article: Restless sleep disorder in a sample of children and adolescents with autism spectrum disorder: preliminary results from a case series
Restless sleep disorder in a sample of children and adolescents with autism spectrum disorder: preliminary results from a case series Open
View article: Metabolomics: Perspectives on Clinical Employment in Autism Spectrum Disorder
Metabolomics: Perspectives on Clinical Employment in Autism Spectrum Disorder Open
Precision medicine is imminent, and metabolomics is one of the main actors on stage. We summarize and discuss the current literature on the clinical application of metabolomic techniques as a possible tool to improve early diagnosis of aut…
View article: Screen exposure and sleep: How the COVID-19 pandemic influenced children and adolescents – A questionnaire-based study
Screen exposure and sleep: How the COVID-19 pandemic influenced children and adolescents – A questionnaire-based study Open
View article: Visual Disturbances Spectrum in Pediatric Migraine
Visual Disturbances Spectrum in Pediatric Migraine Open
Migraine is a complex neurological disorder with partially unknown pathophysiological mechanisms. The prevalence in childhood ranges from 7.7% to 17.8%, thus representing the most frequent primary headache. In half of the cases, migraine i…
View article: Candidate biomarkers from the integration of methylation and gene expression in discordant autistic sibling pairs
Candidate biomarkers from the integration of methylation and gene expression in discordant autistic sibling pairs Open
View article: Learning with fun: the 2nd residential course on child and adolescent psychiatry in Catania, Sicily, endorsed by the ESCAP Research Academy
Learning with fun: the 2nd residential course on child and adolescent psychiatry in Catania, Sicily, endorsed by the ESCAP Research Academy Open
View article: CRISIS AFAR: an international collaborative study of the impact of the COVID-19 pandemic on mental health and service access in youth with autism and neurodevelopmental conditions
CRISIS AFAR: an international collaborative study of the impact of the COVID-19 pandemic on mental health and service access in youth with autism and neurodevelopmental conditions Open
View article: Autism and Neurodevelopmental Disorders: The SARS-CoV-2 Pandemic Implications
Autism and Neurodevelopmental Disorders: The SARS-CoV-2 Pandemic Implications Open
The Special Issue (SI) “Autism and Neurodevelopmental Disorders: The SARS-CoV-2 Pandemic Implications” is an interesting project that adopted a scientific point of view with important implications in clinical and practical fields [...]
View article: Editorial: Internalizing disorders in individuals with autism spectrum disorder
Editorial: Internalizing disorders in individuals with autism spectrum disorder Open
EDITORIAL article Front. Psychiatry, 09 January 2023Sec. Autism Volume 13 - 2022 | https://doi.org/10.3389/fpsyt.2022.1112633
View article: Maternal neuroinflammatory conditions and risk of neurodevelopmental disorders in offspring: a focus on maternal multiple sclerosis and perinatal depression
Maternal neuroinflammatory conditions and risk of neurodevelopmental disorders in offspring: a focus on maternal multiple sclerosis and perinatal depression Open
View article: Suicidality and sleep pattern in autism spectrum disorder: which is the relationship? preliminary report from a pilot study
Suicidality and sleep pattern in autism spectrum disorder: which is the relationship? preliminary report from a pilot study Open
View article: Application of transcranial direct current stimulation combined with cognitive-behavioral therapy for communication and pragmatic skills' improvement in autism spectrum disorder
Application of transcranial direct current stimulation combined with cognitive-behavioral therapy for communication and pragmatic skills' improvement in autism spectrum disorder Open
View article: Modulation of human endogenous retroviruses and cytokines expression in peripheral blood mononuclear cells from autistic children and their parents
Modulation of human endogenous retroviruses and cytokines expression in peripheral blood mononuclear cells from autistic children and their parents Open
View article: Exploring the Link between ADHD and Obesity: A Focus on Temperament
Exploring the Link between ADHD and Obesity: A Focus on Temperament Open
Multiple studies support the relationship between ADHD and overweight/obesity in youth. Different mechanisms may be involved, such as temperamental and psychopathological factors. The aim of this study was to test the hypothesis that speci…