Luigì Santacroce
YOU?
Author Swipe
View article: Association of TORCH Pathogens With Spontaneous Pregnancy Loss: A Prospective Study From Pakistan
Association of TORCH Pathogens With Spontaneous Pregnancy Loss: A Prospective Study From Pakistan Open
This study aimed to determine the prevalence of TORCH infections ( Toxoplasma gondii , Rubella virus, Cytomegalovirus [CMV], and herpes simplex virus [HSV]) among pregnant women reported at Pakistan Institute of Medical Sciences (PIMS) Hos…
View article: Does a link exist between oral microbiota and oral squamous cell carcinoma? A review of current insights
Does a link exist between oral microbiota and oral squamous cell carcinoma? A review of current insights Open
Current literature show a clear role of the oral microbiota in determining and control the evolution of OSCC. Specific interventions on the oral microbiota will help the prevention and management of OSCC in the next future.
View article: Exosomes from Adipose Tissue Mesenchymal Stem Cells, a Preliminary Study for In Vitro and In Vivo Application
Exosomes from Adipose Tissue Mesenchymal Stem Cells, a Preliminary Study for In Vitro and In Vivo Application Open
Mesenchymal stem cells (MSCs), particularly their secreted exosomes, small microvesicles, represent a major focus in regenerative medicine due to their therapeutic potential. Exosomes exhibit growth factors and cytokines and are loaded wit…
View article: Evaluation of Platelet Indices and Reticulated Platelets Using the ADVIA 2120 Analyzer in Patients with Acute Infection or Acute Coronary Syndrome, at Onset
Evaluation of Platelet Indices and Reticulated Platelets Using the ADVIA 2120 Analyzer in Patients with Acute Infection or Acute Coronary Syndrome, at Onset Open
Background: The aim of this study was to evaluate the changes in platelet indices (PLT) provided by the ADVIA 2120 hematology analyzer (Siemens Hematology System) in the early stages of onset of infections and acute coronary syndromes (ACS…
View article: Improved Prognostic Accuracy of NEWS2 Score with Triage Data in Adults with Bacterial Sepsis: A Retrospective Cohort Study
Improved Prognostic Accuracy of NEWS2 Score with Triage Data in Adults with Bacterial Sepsis: A Retrospective Cohort Study Open
Background: It is estimated that most patients with severe sepsis are admitted through the emergency department. Early identification and subsequent early appropriate therapy remain cornerstones of sepsis management. Early recognition of s…
View article: Unveiling the dynamics: understanding the current scenario and drivers of HIV epidemiology in Pakistan
Unveiling the dynamics: understanding the current scenario and drivers of HIV epidemiology in Pakistan Open
Over the past two decades, the global HIV/AIDS pandemic has emerged as one of the most pressing health concerns worldwide. In low-income countries, where resources are scarce, both the prevalence of HIV and the associated mortality rates h…
View article: The Role of Gut Microbiota in Food Allergies and the Potential Role of Probiotics for Their Treatment
The Role of Gut Microbiota in Food Allergies and the Potential Role of Probiotics for Their Treatment Open
The number of food allergies (FAs) is growing, particularly in industrialized countries, resulting in discomfort and a reduction in the quality of life of those who suffer from these allergies. Despite numerous epidemiological studies on F…
View article: The Oral–Gut Microbiota Axis Across the Lifespan: New Insights on a Forgotten Interaction
The Oral–Gut Microbiota Axis Across the Lifespan: New Insights on a Forgotten Interaction Open
The oral–gut microbiota axis is a relatively new field of research. Although most studies have focused separately on the oral and gut microbiota, emerging evidence has highlighted that the two microbiota are interconnected and may influenc…
View article: Probiotics, gut microbiota and physical activity: A close relationship
Probiotics, gut microbiota and physical activity: A close relationship Open
Background: The topic of this review is the study of the gut microbiota (GM), and the use of probiotics, especially in humans, as a new frontier in the field of prevention and health in general. The beneficial effects and functions perform…
View article: Intestinal Microbiota Dysbiosis Role and Bacterial Translocation as a Factor for Septic Risk
Intestinal Microbiota Dysbiosis Role and Bacterial Translocation as a Factor for Septic Risk Open
The human immune system is closely linked to microbiota such as a complex symbiotic relationship during the coevolution of vertebrates and microorganisms. The transfer of microorganisms from the mother’s microbiota to the newborn begins be…
View article: The Role of the Immune Response to Helicobacter pylori Antigens and Its Relevance in Gastric Disorders
The Role of the Immune Response to Helicobacter pylori Antigens and Its Relevance in Gastric Disorders Open
Helicobacter pylori (H.p.) is a Gram-negative bacterium endowed with gastric tropism. H.p. infection is widely spread throughout the world, accounting for various pathologies, such as peptic ulcer, gastric cancer, mucosa-associated lymphoi…
View article: Assessing the Relationship between Lactobacilli and HPV: A Decade of Research
Assessing the Relationship between Lactobacilli and HPV: A Decade of Research Open
The composition of the vaginal microbiota (VMB) influences the health of the female reproductive tract. Several studies have shown how the absence of lactobacilli causes an imbalance in the vaginal microbial community, favoring the develop…
View article: Editorial: Endocrine disruptors in gut endocrinology
Editorial: Endocrine disruptors in gut endocrinology Open
View article: Integrated AI Medical Emergency Diagnostics Advising System
Integrated AI Medical Emergency Diagnostics Advising System Open
The application of AI (Artificial Intelligence) in emergency medicine helps significantly improve the quality of diagnostics under limitations of resources and time constraints in emergency cases. We have designed a comprehensive AI-based …
View article: Hepatitis C Virus: History and Current Knowledge
Hepatitis C Virus: History and Current Knowledge Open
According to the World Health Organization (WHO), the incidence of HCV remains high (around 1.5 million new patients every year), and 80% of patients with acute infection will progress to chronic hepatitis and develop cirrhosis and even li…
View article: Blood Microbiota and Its Products: Mechanisms of Interference with Host Cells and Clinical Outcomes
Blood Microbiota and Its Products: Mechanisms of Interference with Host Cells and Clinical Outcomes Open
In healthy conditions, blood was considered a sterile environment until the development of new analytical approaches that allowed for the detection of circulating bacterial ribosomal DNA. Currently, debate exists on the origin of the blood…
View article: Exploitation of Natural By-Products for the Promotion of Healthy Outcomes in Humans: Special Focus on Antioxidant and Anti-Inflammatory Mechanisms and Modulation of the Gut Microbiota
Exploitation of Natural By-Products for the Promotion of Healthy Outcomes in Humans: Special Focus on Antioxidant and Anti-Inflammatory Mechanisms and Modulation of the Gut Microbiota Open
Daily, a lot of food is wasted, and vegetables, fruit, and cereals as well as marine products represent the major sources of unwanted by-products. The sustainability, waste recovery, and revalorization of food by-products have been propose…
View article: Current View on Major Natural Compounds Endowed with Antibacterial and Antiviral Effects
Current View on Major Natural Compounds Endowed with Antibacterial and Antiviral Effects Open
Nowadays, infectious diseases of bacterial and viral origins represent a serious medical problem worldwide. In fact, the development of antibiotic resistance is responsible for the emergence of bacterial strains that are refractory even to…
View article: May the SSRIs play a role in the onset of peri- and post-menopausal cervical cancer?
May the SSRIs play a role in the onset of peri- and post-menopausal cervical cancer? Open
The emergence of cancer-causing bacteria and viruses that have become resistant to either antibiotics or viral treatment is often attributed to their overuse in people and livestock. Intriguingly, the class of antidepressant drugs, such as…
View article: Current Knowledge about Gastric Microbiota with Special Emphasis on Helicobacter pylori-Related Gastric Conditions
Current Knowledge about Gastric Microbiota with Special Emphasis on Helicobacter pylori-Related Gastric Conditions Open
The gastric milieu, because of its very low acidic pH, is very harsh for bacterial growth. The discovery of Helicobacter pylori (H.p.) has opened a new avenue for studies on the gastric microbiota, thus indicating that the stomach is not a…
View article: Gut Microbiota and Immune System in Necrotizing Enterocolitis and Related Sepsis
Gut Microbiota and Immune System in Necrotizing Enterocolitis and Related Sepsis Open
A severe condition of sepsis can be a complication of necrotizing enterocolitis (NEC), which can occur in premature infants and becomes a medical challenge in the neonatal intensive care unit (NICU). It is a multifactorial intestinal disea…
View article: Human Papillomavirus Carcinogenicity and the Need of New Perspectives: Thoughts from a Retrospective Analysis on Human Papillomavirus Outcomes Conducted at the Hospital University of Bari, Apulia, Italy, between 2011 and 2022
Human Papillomavirus Carcinogenicity and the Need of New Perspectives: Thoughts from a Retrospective Analysis on Human Papillomavirus Outcomes Conducted at the Hospital University of Bari, Apulia, Italy, between 2011 and 2022 Open
Background: The current manuscript’s aim was to determine the human papillomavirus (HPV) genotype-specific prevalence and distribution among individuals, males, and females, of different ages in the region of Apulia, Italy, highlighting th…
View article: Pannonibacter anstelovis sp. nov. Isolated from Two Cases of Bloodstream Infections in Paediatric Patients
Pannonibacter anstelovis sp. nov. Isolated from Two Cases of Bloodstream Infections in Paediatric Patients Open
This study describes two cases of bacteraemia sustained by a new putative Pannonibacter species isolated at the U.O.C. of Microbiology and Virology of the Policlinico of Bari (Bari, Italy) from the blood cultures of two patients admitted t…
View article: SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory Bulbs
SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory Bulbs Open
Background: The COVID-19 pandemic has been a health emergency with a significant impact on the world due to its high infectiousness. The disease, primarily identified in the lower respiratory tract, develops with numerous clinical symptoms…
View article: Current View on How Human Gut Microbiota Mediate Metabolic and Pharmacological Activity of <i>Panax ginseng</i> . A Scoping Review
Current View on How Human Gut Microbiota Mediate Metabolic and Pharmacological Activity of <i>Panax ginseng</i> . A Scoping Review Open
: Panax ginseng is one of the most important remedies in ancient Eastern medicine. In the modern Western world, its reputation started to grow towards the end of the XIX century, but the rather approximate understanding of action mechanism…
View article: A Bird’s-Eye View of the Pathophysiologic Role of the Human Urobiota in Health and Disease: Can We Modulate It?
A Bird’s-Eye View of the Pathophysiologic Role of the Human Urobiota in Health and Disease: Can We Modulate It? Open
For a long time, urine has been considered sterile in physiological conditions, thanks to the particular structure of the urinary tract and the production of uromodulin or Tamm–Horsfall protein (THP) by it. More recently, thanks to the dev…
View article: Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products
Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products Open
Superantigens, i.e., staphylococcal enterotoxins and toxic shock syndrome toxin-1, interact with T cells in a different manner in comparison to conventional antigens. In fact, they activate a larger contingent of T lymphocytes, binding out…
View article: The Creation of Human Epithelial Tissue Graft Derived From Human Blood Cord Mesenchymal Stem Cells and Human Amniotic Membrane to Be Applied in Emergency Care
The Creation of Human Epithelial Tissue Graft Derived From Human Blood Cord Mesenchymal Stem Cells and Human Amniotic Membrane to Be Applied in Emergency Care Open
Due to its outstanding biological properties human amniotic membrane (hAM) has been a topic of medical research for many years in trying to treat, repair and regenerate difficult damages related to the epithelial surface, corneal epithelia…
View article: A study survey on molnupiravir treatment in COVID-19 patients at home in Ninh Thuan province, Vietnam.
A study survey on molnupiravir treatment in COVID-19 patients at home in Ninh Thuan province, Vietnam. Open
MOV caused a reduction in the risk of hospitalization or death in mild COVID-19 patients, and molnupiravir was also found to be well tolerated and safe without any major adverse events during the administration period.
View article: DESAFIOS CONTEMPORÂNEOS EM SAÚDE: PESQUISAS E SOLUÇÕES
DESAFIOS CONTEMPORÂNEOS EM SAÚDE: PESQUISAS E SOLUÇÕES Open
Este livro, publicado pela UniLogos, é fruto do empenho coletivo de acadêmicos, pesquisadores e profissionais dedicados a abordar os desafios complexos e dinâmicos que permeiam o campo da saúde contemporânea. A saúde é um tema crucial que …