Juan Luis Muñoz Bellido
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View article: Aeromonas Infections in Humans—Antibiotic Resistance and Treatment Options
Aeromonas Infections in Humans—Antibiotic Resistance and Treatment Options Open
The genus Aeromonas is widely distributed in aquatic environments, where it is a frequent fish pathogen. It has also been described in association with human infections, with most cases caused by A. caviae, A. veronii biovar sobria, and A.…
View article: <em>Aeromonas </em>Infections in Humans, Antibiotic Resistance and Treatment Options
<em>Aeromonas </em>Infections in Humans, Antibiotic Resistance and Treatment Options Open
The genus Aeromonas is widely distributed in aquatic environments. It is frequent as a fish pathogen, but has also been described associated to human infections. Most human cases are caused by A. caviae, A. veronii biovar sobria, and A. hy…
View article: Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn
Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn Open
This is the first serosurvey conducted in Spain to suggest possible active circulation of the virus in Africans. Our results suggest the need for more extensive clinical and epidemiological studies in Africans to determine the epidemiology…
View article: Three-Month Mortality in Nonhaematological Patients with Chronic Pulmonary Aspergillosis: Differences between Subtypes
Three-Month Mortality in Nonhaematological Patients with Chronic Pulmonary Aspergillosis: Differences between Subtypes Open
Objectives: Chronic pulmonary aspergillosis (CPA) is a fungal lung infection characterised by the slowly progressing destruction of the lung parenchyma and has four main subtypes. The objective of this work was to evaluate the epidemiology…
View article: Three-Month Mortality in Nonhaematological Patients with Chronic Pulmonary Aspergillosis: Differences between Subtypes
Three-Month Mortality in Nonhaematological Patients with Chronic Pulmonary Aspergillosis: Differences between Subtypes Open
(words 232) Objectives: Chronic pulmonary aspergillosis (CPA) is a fungal lung infection characterized by slowly progressive destruction of the lung parenchyma and has four main subtypes. The objective of this work was to evaluate the epid…
View article: Aeromonas Infections in Humans. Antibiotic Resistance and Treatment Options
Aeromonas Infections in Humans. Antibiotic Resistance and Treatment Options Open
The genus Aeromonas is widely distributed in aquatic environments. It is frequent as a fish pathogen, but has also been described associated to human infections. Most human cases are caused by A. caviae, A. veronii biovar sobria, and A. hy…
View article: Azole resistance screening in <i>Aspergillus fumigatus sensu stricto</i> using the azole-containing agar method (EUCAST E.Def 10.2): conidial suspension filtration and inoculum adjustment before inoculum preparation may not be needed
Azole resistance screening in <i>Aspergillus fumigatus sensu stricto</i> using the azole-containing agar method (EUCAST E.Def 10.2): conidial suspension filtration and inoculum adjustment before inoculum preparation may not be needed Open
Azole resistance screening in Aspergillus fumigatus sensu stricto can be routinely carried out by using azole-containing agar plates (E.Def 10.2 procedure); however, conidial suspension filtering and inoculum adjustment before inoculum pre…
View article: Present and Future Applications of Digital PCR in Infectious Diseases Diagnosis
Present and Future Applications of Digital PCR in Infectious Diseases Diagnosis Open
Infectious diseases account for about 3 million deaths per year. The advent of molecular techniques has led to an enormous improvement in their diagnosis, both in terms of sensitivity and specificity and in terms of the speed with which a …
View article: Present and Future Applications of Digital PCR in Infectious Diseases Diagnosis
Present and Future Applications of Digital PCR in Infectious Diseases Diagnosis Open
A Infectious diseases account for about 3 million deaths per year. The advent of molecular techniques has led to an enormous improvement in their diagnosis, both in terms of sensitivity and specificity and in terms of the speed with which …
View article: Screening for Crimean-Congo Haemorrhagic Fever Virus in humans living in an endemic area of Spain.
Screening for Crimean-Congo Haemorrhagic Fever Virus in humans living in an endemic area of Spain. Open
Purpose Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne disease caused by CCHF virus (CCHFV). CCHF is an emerging infectious disease. Recently, the disease has been described in humans in Spain. Most cases have been described in th…
View article: Genomic Insights into Staphylococcus aureus Isolates Exhibiting Diminished Daptomycin Susceptibility
Genomic Insights into Staphylococcus aureus Isolates Exhibiting Diminished Daptomycin Susceptibility Open
Daptomycin is one of the last therapeutic resources for multidrug-resistant gram-positive bacteria. Despite its structural similarities with glycopeptides, its mechanisms of action and resistance are different and in some respects are not …
View article: On the parallelization of multipacting simulation codes for the design of particle accelerator components
On the parallelization of multipacting simulation codes for the design of particle accelerator components Open
Particle trajectory and collision simulation is a critical step of the design and construction of novel particle accelerator components. However it requires a huge computational effort which can slow down the design process. We started fro…
View article: Genetic profile of MRSA and MSSA clinical isolates with daptomycin MIC > 1 mg/L
Genetic profile of MRSA and MSSA clinical isolates with daptomycin MIC > 1 mg/L Open
Daptomycin is one of the last therapeutic resources for multidrug-resistant gram- positive bacteria. Despite its structural similarities with glycopeptides, its mechanisms of action and resistance are different, and in some respects are no…
View article: Circulating tumor DNA (ctDNA) by clonoSEQ to monitor residual disease after axicabtagene ciloleucel (axi‐cel) in large B‐cell lymphoma (LBCL)
Circulating tumor DNA (ctDNA) by clonoSEQ to monitor residual disease after axicabtagene ciloleucel (axi‐cel) in large B‐cell lymphoma (LBCL) Open
Introduction: Most patients (pts) with LBCL respond to axi-cel, but many will eventually experience disease progression (Jacobson et al. JCO. 2020). Monitoring of ctDNA from blood, a minimally invasive diagnostic tool, has been used to ass…
View article: Molecular Diagnosis of Chagas Disease: A Systematic Review and Meta-Analysis.
Molecular Diagnosis of Chagas Disease: A Systematic Review and Meta-Analysis. Open
Background: There is no consensus regarding the most effective molecular protocol for the diagnosis of Chagas disease. The diagnostic tools for Chagas disease are controversial within the scientific community. Currently, serology is the re…
View article: A Novel RT-LAMP for the Detection of Different Genotypes of Crimean–Congo Haemorrhagic Fever Virus in Patients from Spain
A Novel RT-LAMP for the Detection of Different Genotypes of Crimean–Congo Haemorrhagic Fever Virus in Patients from Spain Open
Crimean–Congo haemorrhagic fever (CCHF) is a potentially lethal tick-borne viral disease with a wide distribution. In Spain, 12 human cases of CCHF have been confirmed, with four deaths. The diagnosis of CCHF is hampered by the nonspecific…
View article: Crimean-Congo Hemorrhagic Fever, Spain, 2013–2021
Crimean-Congo Hemorrhagic Fever, Spain, 2013–2021 Open
Crimean-Congo hemorrhagic fever (CCHF) is a viral infectious disease for which distribution of the main vector, Hyalomma spp. ticks, is expanding. We analyzed all 10 cases of CCHF diagnosed in Spain during 2013-2021; case-patient median ag…
View article: Applications of MALDI-TOF Mass Spectrometry to the Identification of Parasites and Arthropod Vectors of Human Diseases
Applications of MALDI-TOF Mass Spectrometry to the Identification of Parasites and Arthropod Vectors of Human Diseases Open
Arthropod vectors and parasites are identified morphologically or, more recently, by molecular methods. Both methods are time consuming and require expertise and, in the case of molecular methods, specific devices. Matrix-assisted laser de…
View article: SMART-LAMP: A Smartphone-Operated Handheld Device for Real-Time Colorimetric Point-of-Care Diagnosis of Infectious Diseases via Loop-Mediated Isothermal Amplification
SMART-LAMP: A Smartphone-Operated Handheld Device for Real-Time Colorimetric Point-of-Care Diagnosis of Infectious Diseases via Loop-Mediated Isothermal Amplification Open
Nucleic acid amplification diagnostics offer outstanding features of sensitivity and specificity. However, they still lack speed and robustness, require extensive infrastructure, and are neither affordable nor user-friendly. Thus, they hav…
View article: How Has the Aspergillosis Case Fatality Rate Changed over the Last Two Decades in Spain?
How Has the Aspergillosis Case Fatality Rate Changed over the Last Two Decades in Spain? Open
(1) Background: Aspergillus produces high morbidity and mortality, especially in at-risk populations. In Spain, the evolution of mortality in recent years due to this fungus is not well established. The aim of this study was to estimate th…
View article: Real-life experience of hepatitis C treatment in a Spanish prison
Real-life experience of hepatitis C treatment in a Spanish prison Open
Background. Hepatitis C virus (HCV) infection is a major public health problem that causes multiple comorbidities. People in prisons who inject intravenous drugs are at increased risk of HCV infection, and HCV infection is 15-fold more pre…
View article: Detection of SARS-CoV-2 RNA in Urine by RT-LAMP: A Very Rare Finding
Detection of SARS-CoV-2 RNA in Urine by RT-LAMP: A Very Rare Finding Open
Detection of SARS-CoV-2 is routinely performed in naso/oropharyngeal swabs samples from patients via RT-qPCR. The RT-LAMP technology has also been used for viral RNA detection in respiratory specimens with both high sensitivity and specifi…
View article: <scp>SARS‐CoV</scp>‐2‐reactive antibody detection after <scp>SARS‐CoV</scp>‐2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group
<span>SARS‐CoV</span>‐2‐reactive antibody detection after <span>SARS‐CoV</span>‐2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group Open
This is a multicenter prospective observational study that included a large cohort ( n = 397) of allogeneic (allo‐HSCT; ( n = 311) and autologous (ASCT) hematopoietic stem cell transplant ( n = 86) recipients who were monitored for antibod…