Luis H. Reyes
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View article: Integrating Generative AI with the Dialogic Model in Education: The Cognitive-AI Synergy Framework (CASF)
Integrating Generative AI with the Dialogic Model in Education: The Cognitive-AI Synergy Framework (CASF) Open
This contribution proposes the Cognitive-AI Synergy Framework (CASF), a novel approach to integrating Generative Artificial Intelligence (GenAI) in education. CASF synthesizes De Zubiría's dialogic pedagogical model with the Artificial Int…
View article: A mathematical phase field model predicts superparamagnetic nanoparticle accelerated fusion of HeLa spheroids for field guided biofabrication
A mathematical phase field model predicts superparamagnetic nanoparticle accelerated fusion of HeLa spheroids for field guided biofabrication Open
In vitro tissue models are crucial for regenerative medicine, drug discovery, and the reduction of animal testing. 3D bioprinting, particularly when utilizing magnetic manipulation of cell spheroids, provides precise control over tissue ar…
View article: A Systemic Approach to Sustainable Technological Extension: A Dynamic Model for Oil Palm Cultivation in Colombia
A Systemic Approach to Sustainable Technological Extension: A Dynamic Model for Oil Palm Cultivation in Colombia Open
This study develops a systemic conceptual model to analyze the dynamics of technological extension and its impact on the sustainability of Colombia’s oil palm production sector. Using a system dynamics-based methodological approach, multip…
View article: The Development of a Kinetic Model for Biochar Gasification with CO2: Comparison Between a Thermogravimetric Analyzer and a Fluidized Bed Reactor
The Development of a Kinetic Model for Biochar Gasification with CO2: Comparison Between a Thermogravimetric Analyzer and a Fluidized Bed Reactor Open
This study presents the development of a kinetic model for the gasification of biochar with carbon dioxide and compares the results obtained using a thermogravimetric analyzer (TGA) and a fluidized bed reactor (FBR). The kinetic experiment…
View article: Nanotheranostics Revolutionizing Gene Therapy: Emerging Applications in Gene Delivery Enhancement
Nanotheranostics Revolutionizing Gene Therapy: Emerging Applications in Gene Delivery Enhancement Open
Nanotheranostics—where nanoscale materials serve both diagnostic and therapeutic functions—are rapidly transforming gene therapy by tackling critical delivery challenges. This review explores the design and engineering of various nanoparti…
View article: Malodorous Gases in Aquatic Environments: A Comprehensive Review from Microbial Origin to Detection and Removal Techniques
Malodorous Gases in Aquatic Environments: A Comprehensive Review from Microbial Origin to Detection and Removal Techniques Open
Malodorous gases—particularly hydrogen sulfide (H2S), ammonia (NH3), and volatile sulfur compounds (VSCs)—significantly degrade water quality, threaten public health, and disrupt ecosystems. Their production stems from microbial activity, …
View article: Evaluating the impact of cell-penetrating motif position on the cellular uptake of magnetite nanoparticles
Evaluating the impact of cell-penetrating motif position on the cellular uptake of magnetite nanoparticles Open
Cell-penetrating peptides (CPPs) have been employed to enhance the cellular uptake and intracellular delivery of various nanocarriers. Among them, nanoparticles (NPs) have been used as suitable vehicles for delivering different bioactive m…
View article: Production and purification of outer membrane vesicles encapsulating green fluorescent protein from Escherichia coli: a step towards scalable OMV technologies
Production and purification of outer membrane vesicles encapsulating green fluorescent protein from Escherichia coli: a step towards scalable OMV technologies Open
Outer membrane vesicles (OMVs) are spherical structures that contain a small fraction of the periplasm of Gram-negative bacteria, surrounded by its outer membrane. They are naturally produced and detached from the bacterial surface, partic…
View article: Enhanced Delivery and Potency of Chemotherapeutics in Melanoma Treatment via Magnetite Nanobioconjugates
Enhanced Delivery and Potency of Chemotherapeutics in Melanoma Treatment via Magnetite Nanobioconjugates Open
Melanoma, known for its aggressive metastatic potential, poses significant treatment challenges. Despite the potent antiproliferative effects of anticancer drugs, systemic toxicity and low water solubility limit their efficacy. This study …
View article: Enhancing Magnetic Micro- and Nanoparticle Separation with a Cost-Effective Microfluidic Device Fabricated by Laser Ablation of PMMA
Enhancing Magnetic Micro- and Nanoparticle Separation with a Cost-Effective Microfluidic Device Fabricated by Laser Ablation of PMMA Open
Superparamagnetic iron oxide micro- and nanoparticles have significant applications in biomedical and chemical engineering. This study presents the development and evaluation of a novel low-cost microfluidic device for the purification and…
View article: Assessment of CRISPRa-mediated gdnf overexpression in an In vitro Parkinson’s disease model
Assessment of CRISPRa-mediated gdnf overexpression in an In vitro Parkinson’s disease model Open
Introduction Parkinson’s disease (PD) presents a significant challenge in medical science, as current treatments are limited to symptom management and often carry significant side effects. Our study introduces an innovative approach to eva…
View article: Zweifach–Fung Microfluidic Device for Efficient Microparticle Separation: Cost-Effective Fabrication Using CO2 Laser-Ablated PMMA
Zweifach–Fung Microfluidic Device for Efficient Microparticle Separation: Cost-Effective Fabrication Using CO2 Laser-Ablated PMMA Open
Microfluidic separators play a pivotal role in the biomedical and chemical industries by enabling precise fluid manipulations. Traditional fabrication of these devices typically requires costly cleanroom facilities, which limits their broa…
View article: Critique: YEASTsim - A Matlab-based simulator for teaching process control in fed-batch yeast fermentations
Critique: YEASTsim - A Matlab-based simulator for teaching process control in fed-batch yeast fermentations Open
One of the primary challenges in chemical engineering education lies in the practical application of theoretical knowledge. Contemporary society demands chemical engineers who are not only adept at critical thinking but also proficient in …
View article: Sound of freshness: Crafting multisensory experience in perfumery
Sound of freshness: Crafting multisensory experience in perfumery Open
The current landscape of the perfume industry faces the challenge of enhancing product appeal and captivating consumers through innovation. Integrating multisensory elements into perfume experiences has the potential to drive this innovati…
View article: Agricultural Extension for Adopting Technological Practices in Developing Countries: A Scoping Review of Barriers and Dimensions
Agricultural Extension for Adopting Technological Practices in Developing Countries: A Scoping Review of Barriers and Dimensions Open
This scoping review employed the PRISMA-ScR framework to dissect the complexities of technological extension in agriculture within developing nations, where varying socio-economic, cultural, and environmental facets deeply influence extens…
View article: Frontiers in stimuli-responsive nanoplatforms: pioneering drug delivery in nanobiotechnology
Frontiers in stimuli-responsive nanoplatforms: pioneering drug delivery in nanobiotechnology Open
Prof. Juan C. Cruz and Prof. Luis H. Reyes introduce the Nanoscale Advances themed issue on Frontiers in Stimuli-Responsive Nanoplatforms: Pioneering Drug Delivery in Nanobiotechnology.
View article: Exploring Crossmodal Associations Between Sound and the Chemical Senses: A Systematic Review Including Interactive Visualizations
Exploring Crossmodal Associations Between Sound and the Chemical Senses: A Systematic Review Including Interactive Visualizations Open
This is the first systematic review that focuses on the influence of product-intrinsic and extrinsic sounds on the chemical senses involving both food and aroma stimuli. This review has a particular focus on all methodological details (sti…
View article: Invertase Immobilization on Magnetite Nanoparticles for Efficient Fructooligosaccharide Generation: A Comprehensive Kinetic Analysis and Reactor Design Strategy
Invertase Immobilization on Magnetite Nanoparticles for Efficient Fructooligosaccharide Generation: A Comprehensive Kinetic Analysis and Reactor Design Strategy Open
This study investigated the effectiveness of immobilizing Saccharomyces cerevisiae invertase (SInv) on magnetite nanoparticles to produce fructooligosaccharides (FOSs). Based on the existing literature and accompanied by parameter estimati…
View article: Trends and prospects in dairy protein replacement in yogurt and cheese
Trends and prospects in dairy protein replacement in yogurt and cheese Open
There is a growing demand for nutritional, functional, and eco-friendly dairy products, which has increased the need for research regarding alternative and sustainable protein sources. Plant-based, single-cell (SCP), and recombinant protei…
View article: Tailoring Magnetite-Nanoparticle-Based Nanocarriers for Gene Delivery: Exploiting CRISPRa Potential in Reducing Conditions
Tailoring Magnetite-Nanoparticle-Based Nanocarriers for Gene Delivery: Exploiting CRISPRa Potential in Reducing Conditions Open
Gene delivery has emerged as a promising alternative to conventional treatment approaches, allowing for the manipulation of gene expression through gene insertion, deletion, or alteration. However, the susceptibility of gene delivery compo…
View article: Unlocking cellular barriers: silica nanoparticles and fullerenol conjugated cell-penetrating agents for enhanced intracellular drug delivery
Unlocking cellular barriers: silica nanoparticles and fullerenol conjugated cell-penetrating agents for enhanced intracellular drug delivery Open
The limited delivery of cargoes at the cellular level is a significant challenge for therapeutic strategies due to the presence of numerous biological barriers. By immobilizing the Buforin II (BUF-II) peptide and the OmpA protein on magnet…
View article: Breaking the clean room barrier: exploring low-cost alternatives for microfluidic devices
Breaking the clean room barrier: exploring low-cost alternatives for microfluidic devices Open
Microfluidics is an interdisciplinary field that encompasses both science and engineering, which aims to design and fabricate devices capable of manipulating extremely low volumes of fluids on a microscale level. The central objective of m…
View article: The Impact of Yeast Encapsulation in Wort Fermentation and Beer Flavor Profile
The Impact of Yeast Encapsulation in Wort Fermentation and Beer Flavor Profile Open
The food and beverage industry is constantly evolving, and consumers are increasingly searching for premium products that not only offer health benefits but a pleasant taste. A viable strategy to accomplish this is through the altering of …