Luís J. del Valle
YOU?
Author Swipe
View article: Doxycycline and carbonated Hydroxyapatite: A synergistic approach to target cancer cells − An in vitro evaluation of the drug loaded nanoparticles and their incorporation into PLA/PEG fibres
Doxycycline and carbonated Hydroxyapatite: A synergistic approach to target cancer cells − An in vitro evaluation of the drug loaded nanoparticles and their incorporation into PLA/PEG fibres Open
Cancer remains as one of the most common causes of mortality worldwide. To develop future treatment strategies, antibiotics are being repurposed to target cancer cells. Among the antibacterials tested, it has been proposed that doxycycline…
View article: Pseudoprotein-poly(ethylene glycol) multi-purpose graft copolymers via Michael addition reaction
Pseudoprotein-poly(ethylene glycol) multi-purpose graft copolymers via Michael addition reaction Open
Amphiphilic biodegradable polymers are of great interest as resorbable micellar drug delivery vehicles, surfactants, and protective coatings for nanoparticles (NPs) providing stealthy properties in vivo, to name a few. The main goal of the…
View article: Optimizing Nanofiltration Membrane Layer-by-Layer Modification: Chemometric and Morphological Insights
Optimizing Nanofiltration Membrane Layer-by-Layer Modification: Chemometric and Morphological Insights Open
Nanofiltration (NF) membranes are essential in wastewater treatment, battery industries, and brine management for selectively removing multivalent ions. However, fouling reduces their lifespan and necessitates harsh cleaning. The layer-by-…
View article: Influence of Nucleating Agents on the Crystallization, Thermal, and Mechanical Properties of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HBHHx)
Influence of Nucleating Agents on the Crystallization, Thermal, and Mechanical Properties of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HBHHx) Open
This study investigates the impact of various nucleating agents on the crystallization behavior, thermal stability, and mechanical properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HBHHx) with 6 mol% 3-hydroxyhexanoate (3HHx) …
View article: The Crystallization Behavior of poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) with Different Nucleating Agents
The Crystallization Behavior of poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) with Different Nucleating Agents Open
This study investigates the impact of various nucleating agents on the crystallization be-havior, thermal stability, and mechanical properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HBHHx) having 6 wt% of 3HHx units, which is …
View article: Genotypic diversity and molecular characterization of DENV-2 in a Peruvian endemic region from 2016 to 2022: displacement of American/Asian genotype
Genotypic diversity and molecular characterization of DENV-2 in a Peruvian endemic region from 2016 to 2022: displacement of American/Asian genotype Open
Background Dengue is the most prevalent acute febrile disease with serious clinical consequences in the tropical and subtropical regions of Asia and America. In Peru, it represents a significant public health issue due to its hyperendemic …
View article: Recent Advances in Combining Waterborne Acrylic Dispersions with Biopolymers
Recent Advances in Combining Waterborne Acrylic Dispersions with Biopolymers Open
Water-based (meth)acrylic (co)polymer dispersions are produced on a large scale for various applications including coatings, adhesives, paints, and construction materials. A major benefit of waterborne polymer dispersions as compared to mo…
View article: The Art of PEGylation: From Simple Polymer to Sophisticated Drug Delivery System
The Art of PEGylation: From Simple Polymer to Sophisticated Drug Delivery System Open
The development of effective drug delivery systems (DDSs) is important for cancer and infectious disease treatment to overcome low bioavailability, rapid clearance and the toxicity of the therapeutic towards non-targeted healthy tissues. T…
View article: The Art of PEGylation: "From Simple Polymer to Sophisticated Drug Delivery System"
The Art of PEGylation: "From Simple Polymer to Sophisticated Drug Delivery System" Open
The development of effective drug delivery systems is a major challenge in cancer therapy, gene therapy, and infectious disease treatment because of its low bioavailability, rapid clearance, and toxicity towards non-targeted healthy tissue…
View article: Electrospun antimicrobial poly(lactic acid) foams with nanocellulose for enhanced hydrophilicity and controlled drug release
Electrospun antimicrobial poly(lactic acid) foams with nanocellulose for enhanced hydrophilicity and controlled drug release Open
This study explores an advanced approach to enhancing the antimicrobial efficacy and drug release of poly(lactic acid) (PLA) scaffolds through the strategic incorporation of cellulose nanocrystals (CNC).
View article: Characterization and Biomedical Applications of Electrospun PHBV Scaffolds Derived from Organic Residues
Characterization and Biomedical Applications of Electrospun PHBV Scaffolds Derived from Organic Residues Open
This study explores the characterization and application of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) synthesized from organic residues, specifically milk and molasses. Six PHBV samples with varying 3-hydroxyvalerate (3HV) conten…
View article: Ultrasonic Molding of Poly(3-hydroxybutyrate) and Its Clay Nanocomposites: Efficient Microspecimens Production with Minimal Material Loss and Degradation
Ultrasonic Molding of Poly(3-hydroxybutyrate) and Its Clay Nanocomposites: Efficient Microspecimens Production with Minimal Material Loss and Degradation Open
Ultrasound micromolding (USM) is an emerging processing technology that offers advantages with regard to spatial resolution, material savings, minimum time residence, minimum exposure to high temperatures, and low cost. Recent advances hav…
View article: Study of Eco-Friendly Unhairing of Skins Using Only Plant-Based Residues
Study of Eco-Friendly Unhairing of Skins Using Only Plant-Based Residues Open
The replacement of sodium sulfide/hydrogen sulfide as unhairing agents in the tanning process is one of the objectives of many recent researches due to its obvious environmental benefits and the potential for improving working conditions. …
View article: Ultrasonic Molding of Poly(3-Hydroxybutyrate) and its Clay Nanocomposites: Efficient Micropieces Production with Minimal Material Loss and Degradation
Ultrasonic Molding of Poly(3-Hydroxybutyrate) and its Clay Nanocomposites: Efficient Micropieces Production with Minimal Material Loss and Degradation Open
Ultrasound micromolding (USM) is an emerging processing technology that offers advantages concerning spatial resolution, material saving, minimum time residence, minimum exposition to high temperatures and low cost. Recent advances have be…
View article: Characterization and Biomedical Applications of Electrospun PHBV Scaffolds Derived from Organic Residues
Characterization and Biomedical Applications of Electrospun PHBV Scaffolds Derived from Organic Residues Open
This study explores the characterization and application of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) synthesized from organic residues, specifically milk and molasses. Six PHBV samples with varying 3-hydroxyvalerate (3HV) conten…
View article: Modeling Polymer Microencapsulation Processes Using CFD and Population Balance Models
Modeling Polymer Microencapsulation Processes Using CFD and Population Balance Models Open
Computational fluid dynamics (CFD) modeling has emerged as a valuable tool for investigating complex processes like microencapsulation. This paper aims to validate the ability of CFD simulations to predict particle size distribution in a p…
View article: Modeling Polymer Microencapsulation Processes using CFD and Population Balance Models
Modeling Polymer Microencapsulation Processes using CFD and Population Balance Models Open
Computational fluid dynamics (CFD) modeling has emerged as a valuable tool for investigating complex processes like microencapsulation. This paper aims to validate the ability of CFD simulations to predict particle size distribution in a p…
View article: PEGylated Micro/Nanoparticles Based on Biodegradable Poly(Ester Amides): Preparation and Study of the Core–Shell Structure by Synchrotron Radiation-Based FTIR Microspectroscopy and Electron Microscopy
PEGylated Micro/Nanoparticles Based on Biodegradable Poly(Ester Amides): Preparation and Study of the Core–Shell Structure by Synchrotron Radiation-Based FTIR Microspectroscopy and Electron Microscopy Open
Surface modification of drug-loaded particles with polyethylene glycol (PEG) chains is a powerful tool that promotes better transport of therapeutic agents, provides stability, and avoids their detection by the immune system. In this study…
View article: Leptospira spp. and Rickettsia spp. as pathogens with zoonotic potential causing acute undifferentiated febrile illness in a central-eastern region of Peru
Leptospira spp. and Rickettsia spp. as pathogens with zoonotic potential causing acute undifferentiated febrile illness in a central-eastern region of Peru Open
Objetive this study was to determine the relationship between acute febrile illness and bacterial pathogens with zoonotic potential that cause emerging and re-emerging diseases in a central-eastern region of Peru. Results Out of the 279 sa…
View article: A Color Indicator Based on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) and a Biodegradable Poly(ester amide) for Detecting Bacterial Contamination
A Color Indicator Based on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) and a Biodegradable Poly(ester amide) for Detecting Bacterial Contamination Open
Bacterial contamination is a hazard in many industries, including food, pharmaceuticals, and healthcare. The availability of a rapid and simple method for detecting this type of contamination in sterile areas enables immediate intervention…
View article: Identification and Clinical Characteristics of Community-Acquired Acinetobacter baumannii in Patients Hospitalized for Moderate or Severe COVID-19 in Peru
Identification and Clinical Characteristics of Community-Acquired Acinetobacter baumannii in Patients Hospitalized for Moderate or Severe COVID-19 in Peru Open
Acinetobacter baumannii has been described as a cause of serious community-acquired infections in tropical countries. Currently, its implications when simultaneously identified with other pathogens are not yet adequately understood. A desc…
View article: Parasitosis by Fasciola hepatica and Variations in Gut Microbiota in School-Aged Children from Peru
Parasitosis by Fasciola hepatica and Variations in Gut Microbiota in School-Aged Children from Peru Open
(1) Background: Human fascioliasis is considered an endemic and hyper-endemic disease in the Peruvian Andean valleys. Our objective was to determine variations in the composition of the gut microbiota among children with Fasciola hepatica …
View article: Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units
Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units Open
This review presents a comprehensive update of the biopolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), emphasizing its production, properties, and applications. The overall biosynthesis pathway of PHBV is explored in detail, hi…
View article: Performance-Enhancing Materials in Medical Gloves
Performance-Enhancing Materials in Medical Gloves Open
Medical gloves, along with masks and gowns, serve as the initial line of defense against potentially infectious microorganisms and hazardous substances in the health sector. During the COVID-19 pandemic, medical gloves played a significant…
View article: Smart Materials in Medical Gloves
Smart Materials in Medical Gloves Open
: Medical gloves, along with masks and gowns, serve as the initial line of defense against poten-tially infectious microorganisms and hazardous substances in the health sector. During the COVID-19 pandemic, medical gloves played a signific…
View article: Supplementary Figure 2 from Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma
Supplementary Figure 2 from Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma Open
PDF file - 66K, Confirmation of human PEL tumor expansion in the xenograft model.
View article: Supplemental Figure Legends from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
Supplemental Figure Legends from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open
Supplemental Figure Legends