Luiz Augusto Perandini
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View article: PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity
PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity Open
View article: Gut Microbiota and Intestinal Epithelial Myd88 Signaling Are Crucial for Renal Injury in UUO Mice
Gut Microbiota and Intestinal Epithelial Myd88 Signaling Are Crucial for Renal Injury in UUO Mice Open
Increasing evidence shows the essential participation of gut microbiota in human health and diseases by shaping local and systemic immunity. Despite an accumulating body of studies showing that chronic kidney disease (CKD) is closely assoc…
View article: Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1 Open
View article: Gut microbial metabolite increases skeletal muscle regeneration through epigenetic mechanisms
Gut microbial metabolite increases skeletal muscle regeneration through epigenetic mechanisms Open
Introduction: Reduction in skeletal muscle regeneration capacity, such as in inflammatory muscle diseases and aging, leads to progressive muscle strength decrement, which impairs mobility and increases risk of falls and mortality, with a n…
View article: TLR2 and TLR4 play opposite role in autophagy associated with cisplatin-induced acute kidney injury
TLR2 and TLR4 play opposite role in autophagy associated with cisplatin-induced acute kidney injury Open
Acute kidney injury (AKI) is considered an inflammatory disease in which toll-like receptors (TLRs) signaling pathways play an important role. The activation of TLRs results in production of several inflammatory cytokines leading to furthe…
View article: Chronic inflammation in skeletal muscle impairs satellite cells function during regeneration: can physical exercise restore the satellite cell niche?
Chronic inflammation in skeletal muscle impairs satellite cells function during regeneration: can physical exercise restore the satellite cell niche? Open
Chronic inflammation impairs skeletal muscle regeneration. Although many cells are involved in chronic inflammation, macrophages seem to play an important role in impaired muscle regeneration since these cells are associated with skeletal …
View article: GLUT4 translocation is not impaired after acute exercise in skeletal muscle of women with obesity and polycystic ovary syndrome
GLUT4 translocation is not impaired after acute exercise in skeletal muscle of women with obesity and polycystic ovary syndrome Open
A single bout of exercise elicited similar GLUT4 translocation in skeletal muscle of PCOS and CTRL, despite a slightly differential pattern of protein phosphorylation. The absence of impairment in GLUT4 translocation suggests that PCOS pat…