Emerson Luiz Botelho Lourenço
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View article: Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs
Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs Open
View article: Genotoxicity study of Cannabis sativa L. extract
Genotoxicity study of Cannabis sativa L. extract Open
View article: Nitric Oxide and Small and Intermediate Calcium-Activated Potassium Channels Mediate the Vasodilation Induced by Apigenin in the Resistance Vessels of Hypertensive Rats
Nitric Oxide and Small and Intermediate Calcium-Activated Potassium Channels Mediate the Vasodilation Induced by Apigenin in the Resistance Vessels of Hypertensive Rats Open
Background: Apigenin (4′,5,7-trihydroxyflavone), a flavonoid with potential cardiovascular benefits, has unclear mechanisms of action. This study investigates its effects on vascular function in Spontaneously Hypertensive Rats (SHRs). Meth…
View article: Successful treatment of two capillary psoriasis patients with cream containing Plinia cauliflora: a case report
Successful treatment of two capillary psoriasis patients with cream containing Plinia cauliflora: a case report Open
Psoriasis is a chronic inflammatory skin condition that can affect any area of the body. It is characterized by reddish, scaling and erythematous lesions, being psoriasis vulgaris or plaque psoriasis the main form of clinical presentation …
View article: Development and Characterization of Film-Forming Solution Loaded with Syzygium cumini (L.) Skeels for Topical Application in Post-Surgical Therapies
Development and Characterization of Film-Forming Solution Loaded with Syzygium cumini (L.) Skeels for Topical Application in Post-Surgical Therapies Open
Background/Objectives: Considering the antioxidant and antimicrobial properties attributed to compounds in Syzygium cumini extract, this research aimed to advance postoperative therapeutic innovations. Specifically, the study assessed the …
View article: Exploring antioxidant and α-glucosidase inhibition in <i>Eugenia</i> L. extracts: a comprehensive phytochemical study
Exploring antioxidant and α-glucosidase inhibition in <i>Eugenia</i> L. extracts: a comprehensive phytochemical study Open
This study analysed extracts obtained from the leaves of Eugenia uniflora, E. involucrata, and E. myrcianthes to determine their chemical composition, antioxidative properties, and α-glucosidase inhibitory capacity. By…
View article: Epidemiological profile of patients with psoriasis
Epidemiological profile of patients with psoriasis Open
Psoriasis is a disease that affects 2 to 3% of the world's population. It is a chronic, non-communicable, painful, and disabling disease for which there is no cure. Thus, this study aims to describe the epidemiological profile, quality of …
View article: ATIVIDADE ANTIMICROBIANA DO EXTRATO HIDROALCOÓLICO DE Tropaeolum majus L. COMO INIBIDOR DE Staphylococcus spp. METICILINA RESISTENTE
ATIVIDADE ANTIMICROBIANA DO EXTRATO HIDROALCOÓLICO DE Tropaeolum majus L. COMO INIBIDOR DE Staphylococcus spp. METICILINA RESISTENTE Open
Atualmente, o gênero Staphylococcus spp. é considerado um dos principais patógenos que causam infecções em seres humanos e animais, e o problema atual é que os novos medicamentos antimicrobianos não acompanharam o número crescente de cepas…
View article: Ateroprotective effects of Plinia cauliflora in. New Zealand rabbits: beyond the lipid-lowering effect
Ateroprotective effects of Plinia cauliflora in. New Zealand rabbits: beyond the lipid-lowering effect Open
Introduction: Plinia cauliflora [Mart.] Kausel (Myrtaceae), popularly known as “jabuticaba,” is a fruit species native to Brazil. Despite extensive widespread usage, its antiatherosclerotic properties' impact remains unknown. Thus, the pre…
View article: Effect of Casearia sylvestrison the obliteration of dentinal tubules and the control of dental sensitivity
Effect of Casearia sylvestrison the obliteration of dentinal tubules and the control of dental sensitivity Open
The present study evaluated the efficacy of the mineralizing action of Casearia sylvestris ethanolic extract on bovine dentin blocks in its pure form and in dental paste, through scanning electron microscopy. The dentin blocks were immerse…
View article: Evaluation of Plinia cauliflora effect in the prevention of osteoporosis in ovariectomized rats
Evaluation of Plinia cauliflora effect in the prevention of osteoporosis in ovariectomized rats Open
Osteoporosis (OSP) decreases bone mass and affects millions of people; the diagnosis is often late. Considering the side effects of conventional treatments, search for natural therapies should be a constant. Among natural treatments, herba…
View article: Prevalence of syphilis cases and other sexually transmitted infections among university students
Prevalence of syphilis cases and other sexually transmitted infections among university students Open
Introduction: Syphilis, caused by Treponema pallidum, is considered one of the main causes of Sexually Transmitted Infections (STIs), due to its easy sexual and congenital transmission. Objective: Knowing the importance of syphilis, this s…
View article: Self-Curing Glass Ionomer Cement Covered by Photopolymerizable Adhesive for Protection of Mucoperiosteal or Gingival Flap Sutures in Canine Oral Surgery
Self-Curing Glass Ionomer Cement Covered by Photopolymerizable Adhesive for Protection of Mucoperiosteal or Gingival Flap Sutures in Canine Oral Surgery Open
Periodontal disease is one of the main affections of the oral cavity of dogs. Its main complication is the formation of periapical abscess, which, when affecting the maxillary canine teeth, can lead to the formation of oronasal fistulae. T…
View article: Extraction Methods, Chemical Characterization, and In Vitro Biological Activities of Plinia cauliflora (Mart.) Kausel Peels
Extraction Methods, Chemical Characterization, and In Vitro Biological Activities of Plinia cauliflora (Mart.) Kausel Peels Open
Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, possesses bioactive compounds such as flavonoids, tannins, and phenolic acids, known for their antioxidant, antibacterial, wound healing, and cardioprotective effects. Theref…
View article: The Use Of Biological Matrices In Forensic Toxicology With Emphasis On Crime Solving
The Use Of Biological Matrices In Forensic Toxicology With Emphasis On Crime Solving Open
Forensic science studies, analyzes, classifies, and determines the elements or substances that have been found at crime scenes, or that may be related to it. The role of investigators is to unravel crimes and thus enable the guilty to be p…
View article: Bioprospecting a Film-Forming System Loaded with Eugenia uniflora L. and Tropaeolum majus L. Leaf Extracts for Topical Application in Treating Skin Lesions
Bioprospecting a Film-Forming System Loaded with Eugenia uniflora L. and Tropaeolum majus L. Leaf Extracts for Topical Application in Treating Skin Lesions Open
Natural products can be used as complements or as alternatives to synthetic drugs. Eugenia uniflora and Tropaeolum majus are natives of Brazil and have antimicrobial, anti-inflammatory, and antioxidant activities. This study aimed to devel…
View article: T. Catappa confers an antioxidant effect to electrospun polyvinyl alcohol nanofibers
T. Catappa confers an antioxidant effect to electrospun polyvinyl alcohol nanofibers Open
In this study, the healing process of full-thickness skin wounds induced in Wistar rats (n = 75) was evaluated, divided into 5 treatments: negative control, PVA nanofiber film, and PVA nanofiber film added in concentrations of 3%, 6% and 1…
View article: Espécies cultivadas no horto de plantas medicinais do campus 2 da UNIPAR com ação anti-inflamatória contra doenças articulares: revisão
Espécies cultivadas no horto de plantas medicinais do campus 2 da UNIPAR com ação anti-inflamatória contra doenças articulares: revisão Open
O tratamento de doenças inflamatórias se dá por meio de fármacos anti-inflamatórios, que exercem inúmeros efeitos colaterais que podem restringir seu uso e a duração. Diante disso, com o intuito de melhorar a saúde dos pacientes que sofrem…
View article: ANÁLISE DA DISPENSAÇÃO DE PÍLULA DO DIA SEGUINTE EM UMA FARMÁCIA DO MUNICÍPIO NO OESTE DO ESTADO DO PARANÁ
ANÁLISE DA DISPENSAÇÃO DE PÍLULA DO DIA SEGUINTE EM UMA FARMÁCIA DO MUNICÍPIO NO OESTE DO ESTADO DO PARANÁ Open
A pílula contraceptiva de emergência (CE) é chamada pelos médicos de pílula anticoncepcional pós-coito. É um método anticoncepcional de emergência e deve ser tomada até 72 horas após a relação sexual. É adequado para casos de abuso sexual,…
View article: PROCEDIMENTOS ESTÉTICOS COM ÊNFASE NA QUEDA CAPILAR
PROCEDIMENTOS ESTÉTICOS COM ÊNFASE NA QUEDA CAPILAR Open
A beleza está diretamente ligada ao aspecto dos cabelos, em todos os tempos e todas as culturas. O cabelo ao longo da vida é sujeito a vários tipos de mudanças, sejam elas naturais ou artificiais, conduzidas por uma vontade de mudar, muita…
View article: POLÍTICAS PÚBLICAS DE MEDICAMENTOS E A RELAÇÃO DE MEDICAMENTOS ESSENCIAIS
POLÍTICAS PÚBLICAS DE MEDICAMENTOS E A RELAÇÃO DE MEDICAMENTOS ESSENCIAIS Open
Através da edição da Norma Operacional de Assistência à Saúde realizada em 2001 e da publicação do Pacto pela Saúde realizado em 2006 o processo de acesso à saúde, ganhou maior ênfase no quesito de inovações e melhorias do sistema de saúde…
View article: Applications of Calcium Oxalate Crystal Microscopy in the Characterization of Baccharis articulata
Applications of Calcium Oxalate Crystal Microscopy in the Characterization of Baccharis articulata Open
Baccharis articulata (Lam.) Pers., popularly known as carqueja, carquejinha or carqueja-doce, is a plant widely used in traditional medicine as a diuretic, digestive and antidiabetic. Due to its similar morphology with other species of the…
View article: Cardioprotective Effects of <i>Solidago microglossa</i> DC. in Nicotine‐Treated Hypertensive Rats
Cardioprotective Effects of <i>Solidago microglossa</i> DC. in Nicotine‐Treated Hypertensive Rats Open
Solidago microglossa DC. (Asteraceae), “arnica brasileira,” is a Brazilian species popularly used to treat hypertension or renal ailments. This study investigated the cardioprotective effects of standardized S. microglossa extract (EESM) i…
View article: REVIEW COVID-19 (SARS-COV-2) AND MEDICINAL PLANTS – LITERATURE
REVIEW COVID-19 (SARS-COV-2) AND MEDICINAL PLANTS – LITERATURE Open
In December 2019, a new coronavirus originating from the city of Wuhan in China started an epidemic that brought many countries into chaos and despair. SARS-CoV-2, as identified, gave rise to the severe acute respiratory syndrome called CO…
View article: Safety Investigations of Two Formulations for Vaginal Use Obtained from Eugenia uniflora L. Leaves in Female Rats
Safety Investigations of Two Formulations for Vaginal Use Obtained from Eugenia uniflora L. Leaves in Female Rats Open
Medicinal plants have great prominence in research into the development of new medicines. Eugenia uniflora L. (Myrtaceae) is an edible and medicinal plant with economic value in the northeast region of Brazil. Several preparations from E. …
View article: TESTE DE SINERGISMO DA ATIVIDADE ANTIMICROBIANA DOS EXTRATOS DE Eugenia uniflora E PRÓPOLIS POR MÉTODO DE CHECKERBOARD
TESTE DE SINERGISMO DA ATIVIDADE ANTIMICROBIANA DOS EXTRATOS DE Eugenia uniflora E PRÓPOLIS POR MÉTODO DE CHECKERBOARD Open
Introdução: A crescente resistência bacteriana aos antibióticos tornou-se uma ameaça à população. Devido ao avanço da fitoterapia nos últimos anos, estudos sobre a ação antimicrobiana de diferentes bioativos têm sido incentivados cada vez …
View article: Perfil sorológico para toxoplasmose em gestantes atendidas em um laboratório de Toledo, Paraná
Perfil sorológico para toxoplasmose em gestantes atendidas em um laboratório de Toledo, Paraná Open
Introdução: A toxoplasmose é uma infecção causada pelo Toxoplasma gondii. Após o contágio, o organismo produz resposta imunológica, levando a imunidade. Para as mulheres, a imunidade é importante para futuras gestações, sendo que nesses ca…
View article: Perfil da utilização de anti-inflamatórios não esteroidais (AINES) em uma Farmácia comunitária do Oeste do Paraná
Perfil da utilização de anti-inflamatórios não esteroidais (AINES) em uma Farmácia comunitária do Oeste do Paraná Open
Introdução: Os medicamentos anti-inflamatórios não esteroides (AINEs) pertencem a uma classe de fármacos amplamente prescritos em todo o mundo, sendo no Brasil, os mais utilizados por automedicação. A automedicação tem se tornado um hábito…
View article: Desafios na inclusão escolar de alunos com transtorno do espectro do autista (TEA) no município de Umuarama-PR durante a pandemia da COVID-19
Desafios na inclusão escolar de alunos com transtorno do espectro do autista (TEA) no município de Umuarama-PR durante a pandemia da COVID-19 Open
Esse estudo objetivou explorar os impasses e desafios sobre o processo de inclusão escolar de alunos com transtorno do espectro do autista (TEA) na cidade de Umuarama-PR durante a pandemia da COVID-19. Os voluntários foram os pais desses a…
View article: Adherence to treatment: a major problem in the control of arterial hypertension
Adherence to treatment: a major problem in the control of arterial hypertension Open
Arterial hypertension (AH) is a polygenic syndrome and comprises several pathophysiological aspects such as genetic predisposition, where heredity plays a considerable role in the origin of the increase in blood pressure levels. AH is the …