Lukas F. Reissig
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View article: Dermal Arteries of the Human Thumb: Arterial Units, Sucquet–Hoyer Canals, and Arterio-Arterial Anastomoses in Pad Versus Tip
Dermal Arteries of the Human Thumb: Arterial Units, Sucquet–Hoyer Canals, and Arterio-Arterial Anastomoses in Pad Versus Tip Open
The dermal arteries of the finger are organized in discrete units. We hypothesized that the anatomy of the dermal arterial units and the number and complexity of dermal Sucquet–Hoyer canals (SHCs) differ between the tip and center of the p…
View article: Age-related changes in platysma insertion height and the clinical role of high-resolution ultrasound in the elderly
Age-related changes in platysma insertion height and the clinical role of high-resolution ultrasound in the elderly Open
View article: Freeze drying and Lugol staining of human menisci reveal circumferential fibre volumes to guide meniscus implant design and virtual simulation
Freeze drying and Lugol staining of human menisci reveal circumferential fibre volumes to guide meniscus implant design and virtual simulation Open
View article: Rib-sparing subclavian vein decompression in venous thoracic outlet syndrome
Rib-sparing subclavian vein decompression in venous thoracic outlet syndrome Open
Our analysis suggests that non-bony decompression with resection of the subclavius muscle and tendon is a safe and effective intervention for the definitive treatment of VTOS that is less invasive than first rib resection.
View article: Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice
Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice Open
Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Its expression is dysregulated in a number of human diseases, including metabolic disorders and certain cancers. Here, we investigate …
View article: “Back Health 24/7/365”—A Novel, Comprehensive “One Size Fits All” Workplace Health Promotion Intervention for Occupational Back Health among Hospital Employees
“Back Health 24/7/365”—A Novel, Comprehensive “One Size Fits All” Workplace Health Promotion Intervention for Occupational Back Health among Hospital Employees Open
Background: Projects for workplace health promotion (WHP) for back pain traditionally focus exclusively on work-related but not on leisure-time stress on the spine. We developed a comprehensive WHP project on the back health of hospital wo…
View article: Characterization, number, and spatial organization of nerve fibers in the human cervical vagus nerve and its superior cardiac branch
Characterization, number, and spatial organization of nerve fibers in the human cervical vagus nerve and its superior cardiac branch Open
The study indicates that selective stimulation of vagal sensory and motor fibers is possible. However, it also highlights the potential risk of activating sympathetic fibers in the superior cardiac branch, especially on the left side.
View article: Integration of freeze-drying and Lugol-enhanced µCT imaging in virtual meniscus modelling for 3D printing and FE analysis
Integration of freeze-drying and Lugol-enhanced µCT imaging in virtual meniscus modelling for 3D printing and FE analysis Open
The knee menisci maintain stability and function of a healthy knee joint. Therefore, degenerative, or traumatic meniscus injuries may require meniscal implants to restore function. The aim of this study was to create a 3D-printable meniscu…
View article: Arterio-venous Anastomoses of the Sucquet–Hoyer Type: Complexity and Distribution in the Human Dermis
Arterio-venous Anastomoses of the Sucquet–Hoyer Type: Complexity and Distribution in the Human Dermis Open
Our study aims at providing detailed information on numbers, form, and spatial distribution of arterio-venous anastomoses of the Sucquet–Hoyer type in the dermis of the nail bed, nail fold corner, thumb pad, arm, nose, glabella, lip, and e…
View article: Why there is a low risk of vascular injury during percutaneous tricortical S1 pedicle screw fixation – A cadaver study
Why there is a low risk of vascular injury during percutaneous tricortical S1 pedicle screw fixation – A cadaver study Open
View article: Preoperative assessment of depressor anguli oris to prevent myectomy failure: An anatomical study using high-resolution ultrasound
Preoperative assessment of depressor anguli oris to prevent myectomy failure: An anatomical study using high-resolution ultrasound Open
High-resolution ultrasound can accurately reveal important preoperative anatomical information in myectomies. Two potential explanations for the surgical failures were discovered: an overlap of lateral DAO muscle fibers over the facial art…
View article: Pre‐clinical evaluation of APrevent® VOIS for unilateral vocal fold paralysis medialization
Pre‐clinical evaluation of APrevent® VOIS for unilateral vocal fold paralysis medialization Open
Objective To evaluate the concept and efficacy of an adjustable implant (Prototype SH30: porcine implant and APrevent® VOIS: human concept) for treatment of unilateral vocal fold paralysis (UVFP) via in vivo mini‐pig studies, human compute…
View article: Surgical Anatomy of Temporalis Muscle Transfer with Fascia Lata Augmentation for the Reanimation of the Paralyzed Face: A Cadaveric Study
Surgical Anatomy of Temporalis Muscle Transfer with Fascia Lata Augmentation for the Reanimation of the Paralyzed Face: A Cadaveric Study Open
Background The temporalis muscle flap transfer with fascia lata augmentation (FLA) is a promising method for smile reconstruction after facial palsy. International literature lacks a detailed anatomical analysis of the temporalis muscle (T…
View article: Selective ansa cervicalis nerve transfer to the marginal mandibular nerve for lower lip reanimation: An anatomical study in cadavers and a case report
Selective ansa cervicalis nerve transfer to the marginal mandibular nerve for lower lip reanimation: An anatomical study in cadavers and a case report Open
Background Donor nerve options for lower lip reanimation are limited in patients undergoing oncological resection of the facial nerve. The ansa cervicalis nerve (ACN) is an advantageously situated donor with great potential but has not bee…
View article: Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants
Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants Open
Careful phenotype analysis of genetically altered mouse embryos/fetuses is vital for deciphering the function of pre- and perinatally lethal genes. Usually this involves comparing the anatomy of mutants with that of wild types of identical…
View article: Spinal cord from body donors is suitable for multicolor immunofluorescence
Spinal cord from body donors is suitable for multicolor immunofluorescence Open
View article: The imprinted <i>Mir483</i> is a growth suppressor and metabolic regulator functioning through IGF1
The imprinted <i>Mir483</i> is a growth suppressor and metabolic regulator functioning through IGF1 Open
Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Here, we uncover the control mechanisms and physiological functions of Mir483 in vivo , by generating constitutive loss-of-function an…
View article: Topographical Mapping of the cardiac autonomic innervation for selective cardiac neuromodulation in pigs and rabbits using MicroCT
Topographical Mapping of the cardiac autonomic innervation for selective cardiac neuromodulation in pigs and rabbits using MicroCT Open
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): Horizon 2020- EU H2020-EU.1.2.2. - FET Proactive "NeuHeart" Nr. 824071 Background & Introduction In recent years, Vagus Nerve Stimulati…
View article: Comparison of surgical techniques for optimal lead placement in sacral neuromodulation: a cadaver study
Comparison of surgical techniques for optimal lead placement in sacral neuromodulation: a cadaver study Open
View article: Ultrasound for the detection of the pyramidal lobe of the thyroid gland
Ultrasound for the detection of the pyramidal lobe of the thyroid gland Open
Purpose The pyramidal lobe (PL) is an ancillary lobe of the thyroid gland that can be affected by the same pathologies as the rest of the gland. We aimed to assess the diagnostic performance of high-resolution sonography in the detection o…
View article: Artefacts in Volume Data Generated with High Resolution Episcopic Microscopy (HREM)
Artefacts in Volume Data Generated with High Resolution Episcopic Microscopy (HREM) Open
High resolution episcopic microscopy (HREM) produces digital volume data by physically sectioning histologically processed specimens, while capturing images of the subsequently exposed block faces. Our study aims to systematically define t…
View article: Cubital tunnel perfusion in different postures—An anatomical investigation
Cubital tunnel perfusion in different postures—An anatomical investigation Open
Introduction/Aims For cubital tunnel syndrome, the avoidance of predisposing arm positions and the use of elbow splints are common conservative treatment options. The rationale is to prevent excessive stretching and compression of the nerv…
View article: The venous system of E14.5 mouse embryos—reference data and examples for diagnosing malformations in embryos with gene deletions
The venous system of E14.5 mouse embryos—reference data and examples for diagnosing malformations in embryos with gene deletions Open
Approximately one‐third of randomly produced knockout mouse lines produce homozygous offspring, which fail to survive the perinatal period. The majority of these die around or after embryonic day (E)14.5, presumably from cardiovascular ins…
View article: Effects and risks of performing a single incision endoscopic plantar fasciotomy — An anatomical study
Effects and risks of performing a single incision endoscopic plantar fasciotomy — An anatomical study Open
Chronic plantar fasciitis with insufficient improvement after conservative treatment can be addressed by surgery. Endoscopic plantar fasciotomy using a single incision technique is an innovative treatment strategy. The aim of this study wa…
View article: Performing nasopharyngeal swabs—Guidelines based on an anatomical study
Performing nasopharyngeal swabs—Guidelines based on an anatomical study Open
Nasopharyngeal swabs are performed to collect material for diagnosing diseases affecting the respiratory system, such as Covid‐19. Yet, no systematic anatomical study defines concrete prerequisites for successfully targeting the nasopharyn…
View article: No functional TRPA1 in cardiomyocytes
No functional TRPA1 in cardiomyocytes Open
Aim There is mounting evidence that TRPA1 has a role in cardiac physiology and pathophysiology. We aim to clarify the site of TRPA1 expression in the heart and in particular whether the channel is expressed in cardiomyocytes. Methods Due t…
View article: Hypoglossal Nerve Abnormalities as Biomarkers for Central Nervous System Defects in Mouse Lines Producing Embryonically Lethal Offspring
Hypoglossal Nerve Abnormalities as Biomarkers for Central Nervous System Defects in Mouse Lines Producing Embryonically Lethal Offspring Open
An essential step in researching human central nervous system (CNS) disorders is the search for appropriate mouse models that can be used to investigate both genetic and environmental factors underlying the etiology of such conditions. Ide…
View article: Standardized fluoroscopy-guided implantation technique enables optimal electrode placement in sacral neuromodulation: a cadaver study
Standardized fluoroscopy-guided implantation technique enables optimal electrode placement in sacral neuromodulation: a cadaver study Open
Background Sacral neuromodulation (SNM) is an established treatment option for patients with faecal incontinence. The location of the stimulating electrode is considered to be essential for treatment success. The purpose of this study was …
View article: A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development Open
View article: The <i>Col4a2</i> <i>em1(IMPC)Wtsi</i> mouse line – lessons from the deciphering the mechanisms of developmental disorders (DMDD) program
The <i>Col4a2</i> <i>em1(IMPC)Wtsi</i> mouse line – lessons from the deciphering the mechanisms of developmental disorders (DMDD) program Open
The Deciphering the Mechanisms of Developmental Disorders (DMDD) program used a systematic and standardised approach to characterise the phenotype of embryos stemming from mouse lines, which produce embryonically lethal offspring. Our stud…