Lukáš Kerner
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View article: Glycosylation of an <i>N</i>‐Acetylated Glucosamine Disaccharide Using an Orthogonally Protected 3‐Iodo‐Kdo Fluoride Donor
Glycosylation of an <i>N</i>‐Acetylated Glucosamine Disaccharide Using an Orthogonally Protected 3‐Iodo‐Kdo Fluoride Donor Open
Kdo (3‐Deoxy‐ d ‐ manno ‐oct‐2‐ulosonic acid) is an essential sugar found in bacterial lipopolysaccharides with significant biomedical relevance. This study introduces an orthogonally protected 3‐iodo‐Kdo fluoride donor and demonstrates it…
View article: Synthesis of <i>C</i> -glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-ʟ-arabinose
Synthesis of <i>C</i> -glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-ʟ-arabinose Open
The incorporation of basic substituents into the structurally conserved domains of cell wall lipopolysaccharides has been identified as a major mechanism contributing to antimicrobial resistance of Gram-negative pathogenic bacteria. Inhibi…
View article: Synthesis of C-glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-L-arabinose
Synthesis of C-glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-L-arabinose Open
Incorporation of basic substituents into the structurally conserved domains of cell-wall lipopolysaccharides has been identified as a major mechanism contributing to antimicrobial resistance of Gram-negative pathogenic bacteria. Inhibition…
View article: CCDC 1492067: Experimental Crystal Structure Determination
CCDC 1492067: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …