Lukas Machegger
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View article: Peri‐ictal imaging abnormalities in non‐convulsive status epilepticus: A systematic review and meta‐analysis comparing magnetic resonance imaging and computed tomography perfusion
Peri‐ictal imaging abnormalities in non‐convulsive status epilepticus: A systematic review and meta‐analysis comparing magnetic resonance imaging and computed tomography perfusion Open
Objective To assess and compare the detection rates of peri‐ictal abnormalities using magnetic resonance imaging (MRI) and computed tomography perfusion (CTP) in patients with non‐convulsive status epilepticus (NCSE). Methods We conducted …
View article: Connectomes in Temporal Lobe and Idiopathic Generalized Epilepsies
Connectomes in Temporal Lobe and Idiopathic Generalized Epilepsies Open
Epilepsy is widely known as a network disease. Ictal and interictal activities are generated and spread within the existing networks involving different regions of the brain. Network alterations affect both grey and white matter, deep brai…
View article: Imaging of Status Epilepticus
Imaging of Status Epilepticus Open
MRI plays an increasingly important role in the diagnosis of status epilepticus (SE). Approximately half of patients with SE do not have pre-existing epilepsy, and the cause of de novo SE is frequently unknown. The role of MRI in the ident…
View article: Epilepsy as primary tumor manifestation correlates with patient status, age, and tumor volume but not with survival in elderly glioblastoma patients: a retrospective bicentric analysis
Epilepsy as primary tumor manifestation correlates with patient status, age, and tumor volume but not with survival in elderly glioblastoma patients: a retrospective bicentric analysis Open
View article: On the value of microsurgical resection compared to biopsy in elderly glioblastoma patients: a retrospective multicenter analysis and scoring system proposal
On the value of microsurgical resection compared to biopsy in elderly glioblastoma patients: a retrospective multicenter analysis and scoring system proposal Open
View article: Brain damage caused by status epilepticus: A prospective MRI study
Brain damage caused by status epilepticus: A prospective MRI study Open
In this prospective study, a proportion of patients displayed cerebral volume loss following a SE. These patients had longer duration and worse outcome of SE. However, the findings should be interpreted with caution due to several limitati…
View article: <scp>Magnetic resonance imaging</scp> fingerprints of status epilepticus: A case–control study
<span>Magnetic resonance imaging</span> fingerprints of status epilepticus: A case–control study Open
Objective Status epilepticus (SE) is frequently associated with peri‐ictal magnetic resonance imaging (MRI) abnormalities (PMA). However, the anatomical distribution of these alterations has not been systematically studied. The aim of this…
View article: NCOG-12. SURVIVAL OF THE ELDERLY: OUTCOMES OF VERY OLD GLIOBLASTOMA PATIENTS – RESULTS FROM AN AUSTRIAN MULTICENTER STUDY
NCOG-12. SURVIVAL OF THE ELDERLY: OUTCOMES OF VERY OLD GLIOBLASTOMA PATIENTS – RESULTS FROM AN AUSTRIAN MULTICENTER STUDY Open
INTRODUCTION Glioblastoma (GBM) outcomes in very old patients remain understudied. Limited data exist on outcomes and treatment options for this specific population, necessitating further research. Materials and METHODS We retrospectively …
View article: Post‐hypoxic status epilepticus – A distinct subtype of status epilepticus with poor prognosis
Post‐hypoxic status epilepticus – A distinct subtype of status epilepticus with poor prognosis Open
Objective To evaluate the clinical outcome of patients with possible and definitive post‐hypoxic status epilepticus (SE) and to describe the SE types in patients with definitive post‐hypoxic SE. Methods Patients with definitive or possible…
View article: Serum Neurofilament Light Chain as Biomarker for Cladribine-Treated Multiple Sclerosis Patients in a Real-World Setting
Serum Neurofilament Light Chain as Biomarker for Cladribine-Treated Multiple Sclerosis Patients in a Real-World Setting Open
Serum neurofilament light chain (sNfL) is an intensely investigated biomarker in multiple sclerosis (MS). The aim of this study was to explore the impact of cladribine (CLAD) on sNfL and the potential of sNfL as a predictor of long-term tr…
View article: Surgeon experience in glioblastoma surgery of the elderly—a multicenter, retrospective cohort study
Surgeon experience in glioblastoma surgery of the elderly—a multicenter, retrospective cohort study Open
View article: The role of epilepsy in elderly patients with Glioblastoma: An Austrian multicenter analysis
The role of epilepsy in elderly patients with Glioblastoma: An Austrian multicenter analysis Open
View article: Unilateral delayed post-hypoxic leukoencephalopathy: a case report
Unilateral delayed post-hypoxic leukoencephalopathy: a case report Open
Background Delayed post-hypoxic leukoencephalopathy is a rare entity following hypoxia. Clinical and radiological signs of delayed post-hypoxic leukoencephalopathy have not previously been reported following acute ischemic stroke. Case pre…
View article: QOL-13. THE ROLE OF EPILEPSY IN ELDERLY PATIENTS WITH GLIOBLASTOMA: AN AUSTRIAN MULTICENTER ANALYSIS
QOL-13. THE ROLE OF EPILEPSY IN ELDERLY PATIENTS WITH GLIOBLASTOMA: AN AUSTRIAN MULTICENTER ANALYSIS Open
BACKGROUND With an aging population, acquisition of a better understanding of prognostic factors in elderly patients with Glioblastoma multiforme (GBM) is of utmost importance. Epileptic seizures have been found to correlate with improved …
View article: P11.49.B MOG antibody positive paraneoplastic brain stem encephalitis associated with cervical cancer: a rare case report
P11.49.B MOG antibody positive paraneoplastic brain stem encephalitis associated with cervical cancer: a rare case report Open
Background Paraneoplastic neurological syndromes are a rare complication of malignant tumors. Myelin oligodendrocyte glycoprotein (MOG) is an important marker on the surface of oligodendrocytes and is associated with many demyelinating dis…
View article: Quantitative Analysis of Diffusion-Restricted Lesions in a Differential Diagnosis of Status Epilepticus and Acute Ischemic Stroke
Quantitative Analysis of Diffusion-Restricted Lesions in a Differential Diagnosis of Status Epilepticus and Acute Ischemic Stroke Open
Background and Purpose Distinction between acute ischemic stroke (AIS) and status epilepticus (SE) on MRI can be challenging as restricted diffusion may occur in both conditions. In this study, we aimed to test a tool, which could help in …
View article: The effect of extracorporeal shock wave therapy in acute traumatic spinal cord injury on motor and sensory function within 6 months post-injury: a study protocol for a two-arm three-stage adaptive, prospective, multi-center, randomized, blinded, placebo-controlled clinical trial
The effect of extracorporeal shock wave therapy in acute traumatic spinal cord injury on motor and sensory function within 6 months post-injury: a study protocol for a two-arm three-stage adaptive, prospective, multi-center, randomized, blinded, placebo-controlled clinical trial Open
View article: A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature
A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature Open
View article: Genotypical glioblastoma of the frontal lobe mimicking ganglioglioma: A case report and review of the literature
Genotypical glioblastoma of the frontal lobe mimicking ganglioglioma: A case report and review of the literature Open
This case of severe phenotype‐genotype mismatch brain tumor morphologically mimicking benign ganglioglioma emphasizes the urgent need for advanced molecular profiling in brain tumor diagnosis in the era of sophisticated molecular profiling.
View article: Tetravalent Influenza Vaccine Is Not Associated With Neuroaxonal Damage in Multiple Sclerosis Patients
Tetravalent Influenza Vaccine Is Not Associated With Neuroaxonal Damage in Multiple Sclerosis Patients Open
Background Efficacy of vaccines and disease activity linked to immunization are major concerns among people with multiple sclerosis (pwMS). Objective To assess antibody responses to seasonal influenza antigens and vaccine-associated neuroa…
View article: The Effect of Extracorporeal Shock Wave Therapy (ESWT) In Acute Traumatic Complete (AIS A) And Incomplete (AIS B-D) Cross-Sectional Lesions On Motor And Sensory Function Within Six Months After Injury: A Two-Arm Three-Stage Adaptive, Prospective, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
The Effect of Extracorporeal Shock Wave Therapy (ESWT) In Acute Traumatic Complete (AIS A) And Incomplete (AIS B-D) Cross-Sectional Lesions On Motor And Sensory Function Within Six Months After Injury: A Two-Arm Three-Stage Adaptive, Prospective, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Open
Background: The pathological mechanism in acute spinal cord injury (SCI) is dual sequential: the primary mechanical lesion and the secondary injury due to a cascade of biochemical and pathological changes initiated by the primary lesion. T…
View article: VarioGuide® frameless neuronavigation-guided stereoelectroencephalography in adult epilepsy patients: technique, accuracy and clinical experience
VarioGuide® frameless neuronavigation-guided stereoelectroencephalography in adult epilepsy patients: technique, accuracy and clinical experience Open
Background Stereoelectroencephalography (SEEG) allows the identification of deep-seated seizure foci and determination of the epileptogenic zone (EZ) in drug-resistant epilepsy (DRE) patients. We evaluated the accuracy and treatment-associ…
View article: Diffuse midline glioma of the cervical spinal cord with H3 K27M genotype phenotypically mimicking anaplastic ganglioglioma: a case report and review of the literature
Diffuse midline glioma of the cervical spinal cord with H3 K27M genotype phenotypically mimicking anaplastic ganglioglioma: a case report and review of the literature Open
View article: Non-convulsive status epilepticus with right arm apraxia: A case report
Non-convulsive status epilepticus with right arm apraxia: A case report Open
Non-convulsive SE (NCSE) is characterized by altered consciousness with or without slight motor manifestations or other phenomena such as aphasia, sensory, auditory, emotional, gustatory or other symptoms. A 69-year-old right-handed man de…
View article: Cerebral Vasculitis in Crohn's Disease: Always a Complication of Inflammatory Bowel Disease or Tumor Necrosis Factor–Alpha Inhibition?
Cerebral Vasculitis in Crohn's Disease: Always a Complication of Inflammatory Bowel Disease or Tumor Necrosis Factor–Alpha Inhibition? Open
Cerebral vasculitis may be a complication of Crohn’s disease (CD) or a side-effect of therapies with biologics including tumor-necrosis factor-alpha antibodies. Here, we report a case of progressive brainstem syndrome and cranial polyneuri…
View article: Do Patients with Implants Experience Strong Sensations That Lead to Early Termination of MRI Examinations?
Do Patients with Implants Experience Strong Sensations That Lead to Early Termination of MRI Examinations? Open
Purpose. Many patients with metallic implants are aware of the potential dangers in an MRI environment. Some implants cause sensations perceptible by the patient during an MRI scan. We wanted to find out if patients having an implant abort…
View article: Computerized Angiographic Occlusion Rating for Ruptured Clipped Aneurysms is Superior to Subjective Occlusion Rating
Computerized Angiographic Occlusion Rating for Ruptured Clipped Aneurysms is Superior to Subjective Occlusion Rating Open
The 2 methods showed remarkable differences in the estimation of the angiographic occlusion rates of clipped aneurysms. The clearly lower interobserver variation of the computerized versus subjective occlusion rating may indicate a superio…