Lukas Scheipner
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View article: Temporal Trends and Differences in Inpatient Palliative Care Use in Metastatic Penile Cancer Patients
Temporal Trends and Differences in Inpatient Palliative Care Use in Metastatic Penile Cancer Patients Open
Objectives: To quantify inpatient palliative care use over time and to test whether patient or hospital characteristics represent determinants of inpatient palliative care use in patients with metastatic penile cancer. Methods: Relying on …
View article: Cancer-specific mortality after radical prostatectomy versus radiotherapy in incidental prostate cancer
Cancer-specific mortality after radical prostatectomy versus radiotherapy in incidental prostate cancer Open
Incidental PCa RT-treated patients exhibited less favorable clinical characteristics than their RP counterparts. Despite full adjustment, RP was associated with a protective effect relative to RT. This effect exclusively applied to the Gle…
View article: Impact of ISUP grade group on cancer-specific mortality in radical prostatectomy-treated prostate cancer patients with organ-confined disease
Impact of ISUP grade group on cancer-specific mortality in radical prostatectomy-treated prostate cancer patients with organ-confined disease Open
Introduction: We aimed to test the impact of International Society of Urological Pathology (ISUP) grade group (GG) on cancer-specific mortality (CSM) in organ-confined (pT2) prostate cancer (PCa) at radical prostatectomy (RP). Methods: RP …
View article: Demographic and Clinical Characteristics of Malignant Solitary Fibrous Tumors: A SEER Database Analysis
Demographic and Clinical Characteristics of Malignant Solitary Fibrous Tumors: A SEER Database Analysis Open
Background/Objectives: Solitary fibrous tumors (SFTs) represent a rare mesenchymal malignancy that can occur anywhere in the body. Due to the low prevalence of the disease, there is a lack of contemporary data regarding patient demographic…
View article: The Effect of Surgical Resection on Cancer-Specific Mortality in Pelvic Soft Tissue Sarcoma According to Histologic Subtype and Stage
The Effect of Surgical Resection on Cancer-Specific Mortality in Pelvic Soft Tissue Sarcoma According to Histologic Subtype and Stage Open
Background/Objectives: The impact of surgical resection versus non-resection on cancer-specific mortality (CSM) in soft tissue pelvic sarcoma remains largely unclear, particularly when considering histologic subtypes such as liposarcoma, l…
View article: Regional Differences in Stage III Nonseminoma Germ Cell Tumor Patients Across SEER Registries
Regional Differences in Stage III Nonseminoma Germ Cell Tumor Patients Across SEER Registries Open
We identified important regional differences in patient, tumor and treatment characteristics, as well as CSM which may be indicative of regional differences in quality of care or expertise in stage III NGSCT management.
View article: Contemporary conditional cancer‐specific survival rates in surgically treated nonmetastatic primary urethral carcinoma
Contemporary conditional cancer‐specific survival rates in surgically treated nonmetastatic primary urethral carcinoma Open
Background We examined the effect of disease‐free interval (DFI) duration on cancer‐specific mortality (CSM)‐free survival, otherwise known as the effect of conditional survival, in radical urethrectomy nonmetastatic primary urethral carci…
View article: The Association between Urinary Diversion Type and Other-Cause Mortality in Radical Cystectomy Patients
The Association between Urinary Diversion Type and Other-Cause Mortality in Radical Cystectomy Patients Open
Background: It is unknown whether more complex UD, such as orthotopic neobladder and abdominal pouch, may be associated with higher OCM rates than ileal conduit. We addressed this knowledge gap within the SEER database 2004–2020. Methods: …
View article: Charlson–Deyo Comorbidity Index as a Novel Predictor for Recurrence in Non-Muscle-Invasive Bladder Cancer
Charlson–Deyo Comorbidity Index as a Novel Predictor for Recurrence in Non-Muscle-Invasive Bladder Cancer Open
Purpose: To test the association between the Charlson–Deyo Comorbidity Index (CCI) and the recurrence of non-muscle-invasive bladder cancer (NMIBC). Methods: NMIBC (Ta, T1, TIS) patients who underwent transurethral resection of bladder tum…
View article: Differences in overall survival of penile cancer patients versus population‐based controls
Differences in overall survival of penile cancer patients versus population‐based controls Open
Purpose To assess whether 5‐year overall survival (OS) of squamous cell carcinoma of the penis (SCCP) patients differs from age‐matched male population‐based controls. Methods We relied on the Surveillance Epidemiology and End Results data…
View article: Editorial Comment on Internet research of utilization of social media in patients with urological disease and their families in Japan
Editorial Comment on Internet research of utilization of social media in patients with urological disease and their families in Japan Open
The authors report that there is no conflict of interest.
View article: ASO Visual Abstract: In-Hospital Venous Thromboembolism and Pulmonary Embolism After Major Urological Cancer Surgery
ASO Visual Abstract: In-Hospital Venous Thromboembolism and Pulmonary Embolism After Major Urological Cancer Surgery Open
After major urological cancer surgeries, venous thromboembolism (VTE) rates increased while pulmonary embolism (PE) rates decreased.Radical cystectomy (RC), radical nephrectomy (RN), and partial nephrectomy (PN) surgeries were associated w…
In-Hospital Venous Thromboembolism and Pulmonary Embolism After Major Urologic Cancer Surgery Open
Background This study aimed to test for temporal trends of in-hospital venous thromboembolism (VTE) and pulmonary embolism (PE) after major urologic cancer surgery (MUCS). Methods In the Nationwide Inpatient Sample (NIS) database (2010–201…
View article: Demographics, Clinical Characteristics and Survival Outcomes of Primary Urinary Tract Malignant Melanoma Patients: A Population-Based Analysis
Demographics, Clinical Characteristics and Survival Outcomes of Primary Urinary Tract Malignant Melanoma Patients: A Population-Based Analysis Open
All primary urinary tract malignant melanoma (ureter vs. bladder vs. urethra) patients were identified from within the Surveillance, Epidemiology, and End Results (SEER) database 2000–2020. Kaplan-Maier plots depicted the overall survival …
View article: Incremental dose-response effect of age on mortality in non-seminoma testis cancer patients
Incremental dose-response effect of age on mortality in non-seminoma testis cancer patients Open
Background Age ≥ 40 predisposes to higher testis cancer-specific mortality (CSM) in non-seminoma. However, it is unknown, whether an incremental dose-response effect applies to subgroups of testis cancer patients (tertiles aged ≥ 40). We t…
View article: Regional differences in metastatic urothelial carcinoma of the urinary bladder patients across the United States SEER registries
Regional differences in metastatic urothelial carcinoma of the urinary bladder patients across the United States SEER registries Open
Introduction: Despite advances in treatment, metastatic urothelial carcinoma of the urinary bladder (mUCUB) is associated with high mortality and treatment risk. We tested for regional differences in mUCUB within a large-scale, population-…
View article: Characteristics of incidental prostate cancer in the United States
Characteristics of incidental prostate cancer in the United States Open
Background: Data regarding North-American incidental (cT1a/b) prostate cancer (PCa) patients is scarce. To address this, incidental PCa characteristics (age, PSA values at diagnosis, Gleason score [GS]), subsequent treatment and cancer-spe…
View article: Critical Appraisal of Leibovich 2018 and GRANT Models for Prediction of Cancer-Specific Survival in Non-Metastatic Chromophobe Renal Cell Carcinoma
Critical Appraisal of Leibovich 2018 and GRANT Models for Prediction of Cancer-Specific Survival in Non-Metastatic Chromophobe Renal Cell Carcinoma Open
Within the Surveillance, Epidemiology, and End Results database (2000–2019), we identified 5522 unilateral surgically treated non-metastatic chromophobe kidney cancer (chRCC) patients. This population was randomly divided into development …
View article: Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages
Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages Open
Background and Objectives: The impact of pure histological subtypes in testicular non-seminoma germ cell tumors on survival, specifically regarding pure embryonal carcinoma, is not well established. Therefore, this study aimed to test for …
View article: The AST/ALT Ratio Is an Independent Prognostic Marker for Disease-free Survival in Stage II and III Colorectal Carcinoma
The AST/ALT Ratio Is an Independent Prognostic Marker for Disease-free Survival in Stage II and III Colorectal Carcinoma Open
In this study, the serum AST/ALT ratio emerged as a valid prognostic marker for DFS in non-metastatic colorectal cancer patients at stage II and III.
Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial Open
Background: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for thi…