Lukas Wimmer
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View article: Size and end-group chemistry of linear polyethylene terephthalate oligomers matter in chemical risk assessment
Size and end-group chemistry of linear polyethylene terephthalate oligomers matter in chemical risk assessment Open
Cyclic and linear oligomers, formed as side-products during PET polymerization, are poorly characterized non-intentionally added substances (NIAS) in food. Risk assessment of PET oligomers is challenging due to their size, number, isomeris…
View article: Quality-by-design and current good practices for the production of test and reference materials for micro- and nano-plastic research
Quality-by-design and current good practices for the production of test and reference materials for micro- and nano-plastic research Open
Understanding the environmental and human health impacts of micro- and nanoplastic pollutants is currently a high priority, stimulating intensive methodological research work in the areas of sampling, sample preparation and detection as we…
View article: Effects of Polypropylene and Polyethylene Terephthalate Microplastics on Trypsin Structure and Function
Effects of Polypropylene and Polyethylene Terephthalate Microplastics on Trypsin Structure and Function Open
Ingestion is one of the main exposure routes of humans and animals to microplastics (MPs). During digestion, MPs can interact with both gastrointestinal enzymes and food proteins. This study investigated the adsorption of trypsin onto poly…
View article: Effects of Polypropylene and Polyethylene Terephthalate Microplastics on Trypsin Structure and Function
Effects of Polypropylene and Polyethylene Terephthalate Microplastics on Trypsin Structure and Function Open
Ingestion is one of the main exposure routes of humans to microplastics (MPs). During digestion, MPs can interact with both gastrointestinal enzymes and food proteins. This study investigated adsorption of trypsin to polypropylene (PP) and…
View article: The Invisible Footprint of Climbing Shoes: High Exposure to Rubber Additives in Indoor Facilities
The Invisible Footprint of Climbing Shoes: High Exposure to Rubber Additives in Indoor Facilities Open
There is growing concern about rubber-derived compounds (RDCs), predominantly originating from tire and road wear particles. Other consumer products, including sports equipment, also contain RDCs, and human exposure to these compounds is o…
View article: A quality-by-design inspired approach to develop PET and PP nanoplastic test materials for use in <i>in vitro</i> and <i>in vivo</i> biological assays
A quality-by-design inspired approach to develop PET and PP nanoplastic test materials for use in <i>in vitro</i> and <i>in vivo</i> biological assays Open
QbD-based production of PET and PP nanoplastics for biological assays.
View article: The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities
The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities Open
There is growing concern about rubber-derived compounds (RDCs), predominantly originating from tire and road wear particles. Other consumer products, including sports equipment, also contain RDCs and human exposure to these compounds is of…
View article: The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities
The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities Open
There is increasing research focused on rubber additives, predominantly originating from tire and road wear particles. Other consumer products including sports equipment also contain rubber additives and the overall human exposure to these…
View article: The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities
The invisible footprint of climbing shoes: high exposure to rubber additives in indoor facilities Open
There is increasing research focused on rubber additives, predominantly originating from tire and road wear particles. Other consumer products including sports equipment also contain rubber additives and the overall human exposure to these…
View article: Inhalation of climbing shoe particles is highly relevant for the human exposure to rubber-derived chemicals in indoor facilities
Inhalation of climbing shoe particles is highly relevant for the human exposure to rubber-derived chemicals in indoor facilities Open
There is increasing research focused on rubber-derived chemicals (RDCs), predominantly originating from tire and road wear particles. Other consumer products also contain RDCs, but the overall human exposure to these compounds is unknown. …
View article: Small polystyrene microplastics interfere with the breakdown of milk proteins during static in vitro simulated human gastric digestion
Small polystyrene microplastics interfere with the breakdown of milk proteins during static in vitro simulated human gastric digestion Open
Human ingestion of microplastics (MPs) is common and inevitable due to the widespread contamination of food items, but implications on the gastric digestion of food proteins are still unknown. In this study, the interactions between pepsin…
View article: LogP of N-acyl-gemcitabine and lectin-corona emerge as key parameters in nanoparticulate intravesical cancer therapy
LogP of N-acyl-gemcitabine and lectin-corona emerge as key parameters in nanoparticulate intravesical cancer therapy Open
After surgical removal of the tumour tissue, bladder cancer is treated by intravesical instillation of cytotoxic drugs such as gemcitabine. Gemcitabine, however, is highly hydrophilic and possesses a short half-life due to fast enzymatic d…