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View article: Cornelian Cherry (Cornus mas) Fruit Extract Administration in Sleep Deprived Wistar Rats—Friend or Foe?
Cornelian Cherry (Cornus mas) Fruit Extract Administration in Sleep Deprived Wistar Rats—Friend or Foe? Open
Supplement use has increased in recent years, despite limited evidence for its broad health benefits. Furthermore, exogenous antioxidants may determine pro-oxidant effects, depending on various factors such as dose, circadian window, and p…
View article: INFLUENCE OF DIFFERENT SWEETENERS ON THE TOTAL ANTHOCYANIN CONTENT OF HOMEMADE FOREST FRUIT JAM
INFLUENCE OF DIFFERENT SWEETENERS ON THE TOTAL ANTHOCYANIN CONTENT OF HOMEMADE FOREST FRUIT JAM Open
Anthocyanins, natural water-soluble pigments, responsible for the red, purple and blue colors in many fruits, are valued for their nutritional properties in fruit-based food products such as jams. However, their stability during storage is…
View article: The Impact of Hybrid Bionanomaterials Based on Gold Nanoparticles on Liver Injury in an Experimental Model of Thioacetamide-Induced Hepatopathy
The Impact of Hybrid Bionanomaterials Based on Gold Nanoparticles on Liver Injury in an Experimental Model of Thioacetamide-Induced Hepatopathy Open
The present study aimed to evaluate the therapeutic benefits of a hybrid material based on gold nanoparticles and natural extracts on an experimental model of thioacetamide-induced (TAA) liver injury in rats. The nanomaterials were synthes…
View article: Molecular Effects of Cornelian Cherry Fruit (Cornus mas L.) Extract on Sleep Deprivation-Induced Oxidative Stress, Cytokine Dysregulation, and Behavioural Changes in Wistar Rats
Molecular Effects of Cornelian Cherry Fruit (Cornus mas L.) Extract on Sleep Deprivation-Induced Oxidative Stress, Cytokine Dysregulation, and Behavioural Changes in Wistar Rats Open
Sleep deprivation (SD) induces significant neurobiological changes, including oxidative stress, neuroinflammation, and behavioural impairments. This study was designed as a proof of concept to assess the potential for modulating the effect…
View article: Doxorubicin Incorporation into Gold Nanoparticles: An In Vivo Study of Its Effects on Cardiac Tissue in Rats
Doxorubicin Incorporation into Gold Nanoparticles: An In Vivo Study of Its Effects on Cardiac Tissue in Rats Open
Gold nanoparticles (Au-NPs) have been explored as potential vectors for enhancing the antitumor efficacy of doxorubicin (DOX) while minimizing its cardiotoxic effects. However, the impacts of DOX Au-NPs on cardiac function and oxidative st…
View article: Hepatic changes following a high-fat diet: effects of Cornus mas and gold nanoparticles phytoreduced with Cornus mas on oxidative stress, inflammation, and histological damage
Hepatic changes following a high-fat diet: effects of Cornus mas and gold nanoparticles phytoreduced with Cornus mas on oxidative stress, inflammation, and histological damage Open
Background and aims. High fat diet (HFD) can lead to liver injury, through oxidative stress and inflammation. The use of natural compounds with antioxidant and anti-inflammatory properties can have a protective potential. We aimed to inves…
View article: Gold Nanoparticles Synthesized with Natural Compounds: Assesment of Antioxidant Activity After In Vitro Digestion
Gold Nanoparticles Synthesized with Natural Compounds: Assesment of Antioxidant Activity After In Vitro Digestion Open
Currently, gold nanoparticles (GNPs) are considered an ideal delivery system due to their physiological stability, high bioactivity, and controlled release of biological component. Our primary objective was to comprehend the behavior of go…
View article: Effects of gold nanoparticles phytoreduced with Cornus mas L. extract on the aorta wall function in rats with hyperlipid diet – a study on isolated aortic rings
Effects of gold nanoparticles phytoreduced with Cornus mas L. extract on the aorta wall function in rats with hyperlipid diet – a study on isolated aortic rings Open
Background. Vascular reactivity may be influenced by the dysfunction of the perivascular adipose tissue (PVAT) that occurs after a prolonged high fat diet (HFD). Aim. The aim of this study was to investigate the vascular responses in rats …
View article: Hybrid Material Based on Vaccinium myrtillus L. Extract and Gold Nanoparticles Reduces Oxidative Stress and Inflammation in Hepatic Stellate Cells Exposed to TGF-β
Hybrid Material Based on Vaccinium myrtillus L. Extract and Gold Nanoparticles Reduces Oxidative Stress and Inflammation in Hepatic Stellate Cells Exposed to TGF-β Open
(1) Background: The study aimed to investigate the impact of gold nanoparticles capped with Cornus sanguinea (NPCS) and mixed with a fruit extract (Vaccinum myrtillus L.—VL) on human hepatic stellate cells (LX-2) exposed to TGF-β. (2) Meth…
View article: Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts
Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts Open
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance and inflammation triggered by hyperglycaemia. Plant-based therapies are characterised by low tissue bioavailability. The …
View article: Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts
Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts Open
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance and inflammation triggered by hyperglycemia. Plant-based therapies are characterized by low bioavailability in ocular tis…
View article: Goji-Berry-Mediated Green Synthesis of Gold Nanoparticles and Their Promising Effect on Reducing Oxidative Stress and Inflammation in Experimental Hyperglycemia
Goji-Berry-Mediated Green Synthesis of Gold Nanoparticles and Their Promising Effect on Reducing Oxidative Stress and Inflammation in Experimental Hyperglycemia Open
The present report focuses on a rapid and convenient method applicable in the green synthesis of gold nanoparticles (AuNPs) using goji berry (Lycium barbarum—LB) extracts rich in antioxidant compounds, as well as on the structural analysis…
View article: Green Synthesized Gold and Silver Nanoparticles Increased Oxidative Stress and Induced Cell Death in Colorectal Adenocarcinoma Cells
Green Synthesized Gold and Silver Nanoparticles Increased Oxidative Stress and Induced Cell Death in Colorectal Adenocarcinoma Cells Open
The research investigated the effect of gold (Au-CM) and silver nanoparticles (Ag-CM) phytoreduced with Cornus mas fruit extract (CM) on a human colorectal adenocarcinoma (DLD-1) cell line. The impact of nanoparticles on the viability of D…
View article: Effects of Gold Nanoparticles Functionalized with Cornus mas L. Fruit Extract on the Aorta Wall in Rats with a High-Fat Diet and Experimental-Induced Diabetes Mellitus—An Imaging Study
Effects of Gold Nanoparticles Functionalized with Cornus mas L. Fruit Extract on the Aorta Wall in Rats with a High-Fat Diet and Experimental-Induced Diabetes Mellitus—An Imaging Study Open
Diabetes mellitus and high-fat diets trigger the mechanisms that alter the walls of blood vessels. Gold nanoparticles, as new pharmaceutical drug delivery systems, may be used in the treatment of different diseases. In our study, the aorta…
View article: OPTIMIZATION OF THE ECO-FRIENDLY SYNTHESIS OF SILVER NANOPARTICLES USING GOJI BERRIES’ BIOACTIVE COMPOUNDS
OPTIMIZATION OF THE ECO-FRIENDLY SYNTHESIS OF SILVER NANOPARTICLES USING GOJI BERRIES’ BIOACTIVE COMPOUNDS Open
The numerous applications of metallic nanoparticles in different fields such as materials science, medicine, biology, led to the rapid development of various synthesis methods of these nanomaterials, among which the biogenic approach in ob…
View article: Oxidative stress, inflammation and biochemical parameters in rats on high fat diet and experimentallz induced diabetes mellitus after the administration of Cornus mas L. extract
Oxidative stress, inflammation and biochemical parameters in rats on high fat diet and experimentallz induced diabetes mellitus after the administration of Cornus mas L. extract Open
View article: Effects of Gold Nanoparticles Functionalized with Bioactive Compounds from Cornus mas Fruit on Aorta Ultrastructural and Biochemical Changes in Rats on a Hyperlipid Diet—A Preliminary Study
Effects of Gold Nanoparticles Functionalized with Bioactive Compounds from Cornus mas Fruit on Aorta Ultrastructural and Biochemical Changes in Rats on a Hyperlipid Diet—A Preliminary Study Open
Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory activity. Gold nanoparticles (AuNPs) are considered potent delivery systems and may be used to release pharmaceutical compounds at the level of injury. In…
View article: <i>Viburnum opulus</i>fruit extract-capped gold nanoparticles attenuated oxidative stress and acute inflammation in carrageenan-induced paw edema model
<i>Viburnum opulus</i>fruit extract-capped gold nanoparticles attenuated oxidative stress and acute inflammation in carrageenan-induced paw edema model Open
This study designed, characterized, and investigated the antioxidant and anti-inflammatory effects of gold nanoparticles coated with Viburnum opulus extract (AuNP-VO) compared to those of Viburnum opulus fruit extract (VO) and indomethacin…
View article: The effects of ellagic acid-coated gold nanoparticles on oxidative stress in experimentally induced inflammation
The effects of ellagic acid-coated gold nanoparticles on oxidative stress in experimentally induced inflammation Open
View article: Neurobehavioral and Ultrastructural Changes Induced by Phytosynthesized Silver-Nanoparticle Toxicity in an In Vivo Rat Model
Neurobehavioral and Ultrastructural Changes Induced by Phytosynthesized Silver-Nanoparticle Toxicity in an In Vivo Rat Model Open
(1) Background: The study aimed to assess neurobehavioral, ultrastructural, and biochemical changes induced by silver nanoparticles synthesized with Cornus mas L. extract (AgNPs-CM) in rat brains. (2) Methods: The study included 36 male ad…
View article: Aorta modifications in oral gold nanoparticles administration in rats
Aorta modifications in oral gold nanoparticles administration in rats Open
View article: Aorta modifications in oral gold nanoparticles administration in rats
Aorta modifications in oral gold nanoparticles administration in rats Open
View article: Influence of Different Sweeteners on the Stability of Anthocyanins from Cornelian Cherry Juice
Influence of Different Sweeteners on the Stability of Anthocyanins from Cornelian Cherry Juice Open
Cornelian cherries are red fruits which can be considered as a valuable dietary source of antioxidant biologically active compounds, especially anthocyanins. The purpose of the present study was to investigate the anthocyanins degradation …
View article: EFFECT OF SOME ANTIOXIDANT FOOD ADDITIVES ON THE DEGRADATION OF CORNELIAN CHERRY ANTHOCYANINS
EFFECT OF SOME ANTIOXIDANT FOOD ADDITIVES ON THE DEGRADATION OF CORNELIAN CHERRY ANTHOCYANINS Open
Anthocyanin rich fruits present a great potential as source of natural food colorants. Their use in the food industry is limited by their low stability. The influence of storage media and addition of three widely used antioxidant food addi…
View article: Green Synthesis of Biogenic Silver Nanoparticles for Efficient Catalytic Removal of Harmful Organic Dyes
Green Synthesis of Biogenic Silver Nanoparticles for Efficient Catalytic Removal of Harmful Organic Dyes Open
The present article reports an environmentally benign method for synthesizing silver nanoparticles using the fruit extract of Viburnum opulus L. as a source of bioactive compounds, which can act as reducing agents of the silver ions and al…
View article: DEGRADATION KINETICS OF ANTHOCYANINS DURING HEAT TREATMENT OF WILD BLACKTHORN (Prunus spinosa L.) FRUITS EXTRACT
DEGRADATION KINETICS OF ANTHOCYANINS DURING HEAT TREATMENT OF WILD BLACKTHORN (Prunus spinosa L.) FRUITS EXTRACT Open
The blackthorn (Prunus spinosa L.) fruits are known as a valuable source of anthocyanins and for their high antioxidant capacity. The aim of the present study was to investigate the thermal stability of anthocyanins from blackthorn fruits,…
View article: Effects of In Vitro Gastrointestinal Digestion on the Antioxidant Capacity and Anthocyanin Content of Cornelian Cherry Fruit Extract
Effects of In Vitro Gastrointestinal Digestion on the Antioxidant Capacity and Anthocyanin Content of Cornelian Cherry Fruit Extract Open
Red fruits are considered a major source of antioxidant compounds in the human diet. They usually contain anthocyanins, phenolic pigments that confer them multiple health-promoting properties. The health benefits of these bioactive phytoco…
View article: Biosynthesis of Silver Nanoparticles Using Ligustrum Ovalifolium Fruits and Their Cytotoxic Effects
Biosynthesis of Silver Nanoparticles Using Ligustrum Ovalifolium Fruits and Their Cytotoxic Effects Open
The present study reports for the first time the efficacy of bioactive compounds from Ligustrum ovalifolium L. fruit extract as reducing and capping agents of silver nanoparticles (AgNPs), developing a green, zero energetic, cost effective…
View article: IMPACT OF THERMAL TREATMENT ON THE ANTIOXIDANT ACTIVITY OF CORNELIAN CHERRIES EXTRACT
IMPACT OF THERMAL TREATMENT ON THE ANTIOXIDANT ACTIVITY OF CORNELIAN CHERRIES EXTRACT Open
The present study aims to investigate the influence of the temperature on the radical scavenging capacity (measured by the 2, 2-azinobis (3-ethylbenzothiazolyne-6-sulphonic acid) diammonium salt radical cation assay) and ferric reducing an…
View article: Antioxidant activity of Cornelian cherry (Cornus mas L.) fruits extract and the in vivo evaluation of its anti-inflammatory effects
Antioxidant activity of Cornelian cherry (Cornus mas L.) fruits extract and the in vivo evaluation of its anti-inflammatory effects Open