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View article: Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania
Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania Open
Introduction: Dysgeusia has been regarded as a clinical feature associated with SARS-CoV-2 infection since the onset of the pandemic. The initial circulating variants were linked to the presence of dysgeusia; however, with the emergence of…
View article: The Incidence and Characteristics of Oral Candidiasis in Patients Hospitalized for SARS-CoV-2 Infection During the Circulation of Alpha, Beta, and Delta Variants
The Incidence and Characteristics of Oral Candidiasis in Patients Hospitalized for SARS-CoV-2 Infection During the Circulation of Alpha, Beta, and Delta Variants Open
Background: Oral candidiasis has been documented in patients with SARS-CoV-2 infection, with varying prevalence rates across geographic regions and patient demographics. This study aimed to ascertain the incidence, characteristics, and ris…
View article: The Clinical Effectiveness and Tolerability of Oseltamivir in Unvaccinated Pediatric Influenza Patients during Two Influenza Seasons after the COVID-19 Pandemic: The Impact of Comorbidities on Hospitalization for Influenza in Children
The Clinical Effectiveness and Tolerability of Oseltamivir in Unvaccinated Pediatric Influenza Patients during Two Influenza Seasons after the COVID-19 Pandemic: The Impact of Comorbidities on Hospitalization for Influenza in Children Open
Antiviral therapy such as oseltamivir has been recommended for hospitalized children with suspected and confirmed influenza for almost 20 years. The therapy is officially authorized for newborns two weeks of age or older, however, question…
View article: The Clinical Effectiveness and Tolerability of Oseltamivir in Unvaccinated against Influenza Pediatric Patients in Two In-fluenza seasons after the COVID-19 pandemic.The Impact of Comorbidities on Hospitalization for Influenza in Children.
The Clinical Effectiveness and Tolerability of Oseltamivir in Unvaccinated against Influenza Pediatric Patients in Two In-fluenza seasons after the COVID-19 pandemic.The Impact of Comorbidities on Hospitalization for Influenza in Children. Open
Antiviral therapy such as Oseltamivir has been recommended for hospitalized children with suspected and confirmed influenza for almost 20 years. The therapy is officially authorized for newborns two weeks of age or older, however, question…
View article: Hybrid Immunity and the Incidence of SARS-CoV-2 Reinfections during the Omicron Era in Frontline Healthcare Workers
Hybrid Immunity and the Incidence of SARS-CoV-2 Reinfections during the Omicron Era in Frontline Healthcare Workers Open
During the coronavirus disease (COVID-19) pandemic healthcare workers (HCWs) acquired immunity by vaccination or exposure to multiple variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our study is a comparative anal…
View article: Rare fatal case of purpura fulminans due to pneumococcal sepsis in a child, associated with multiorgan failure
Rare fatal case of purpura fulminans due to pneumococcal sepsis in a child, associated with multiorgan failure Open
We aim to report a rare case of PF associated with pneumococcal meningoencephalitis in an immunocompetent child, to better appreciate the risk of fatal evolution when managing this disease in children.
View article: The Dynamic Risk of COVID-19-Related Events in Vaccinated Healthcare Workers (HCWs) from a Tertiary Hospital in Bucharest, Romania: A Study Based on Active Surveillance Data
The Dynamic Risk of COVID-19-Related Events in Vaccinated Healthcare Workers (HCWs) from a Tertiary Hospital in Bucharest, Romania: A Study Based on Active Surveillance Data Open
Our study describes the frequency and severity of COVID-19 in HCWs and estimates the dynamic risk of COVID-19-related events. We actively surveyed all HCWs from a tertiary infectious disease hospital from 26 February 2020 to 31 May 2023. O…
View article: Clinico-etiological and epidemiological particularities of respiratory virus diseases in children in the 2022-2023 season
Clinico-etiological and epidemiological particularities of respiratory virus diseases in children in the 2022-2023 season Open
In the period 2020-2022 as a result of epidemiological measures specific to the COVID-19 pandemic (protective mask, online teaching activity, social distancing) we witnessed a considerable decrease in the number of cases of respiratory vir…
View article: Clinical Features and Outcomes of the Association of Co-Infections in Children with Laboratory-Confirmed Influenza during the 2022–2023 Season: A Romanian Perspective
Clinical Features and Outcomes of the Association of Co-Infections in Children with Laboratory-Confirmed Influenza during the 2022–2023 Season: A Romanian Perspective Open
The 2022–2023 influenza season in Romania was characterized by high pediatric hospitalization rates, predominated due to influenza A subtypes (H1N1) pdm09 and H3N2. The lowered population immunity to influenza after the SARS-CoV-2 pandemic…
View article: Clinical Features and Outcomes of Association of Co-infections in Children with LaboratoryConfirmed Influenza, during 2022–2023 Season; a Romanian Perspective
Clinical Features and Outcomes of Association of Co-infections in Children with LaboratoryConfirmed Influenza, during 2022–2023 Season; a Romanian Perspective Open
The 2022-2023 influenza season in Romania was characterized by high pediatric hospitalization rates, predominated by influenza A subtypes H1N1 and H3N2. Lowered population immunity to influenza after the SARS-CoV-2 pandemic and subsequent …
View article: Rare Fatal Case of Purpura Fulminans with Acute Kidney Injury, Due to Pneumococcal Sepsis in Children, Associated with Multiorgan Failure
Rare Fatal Case of Purpura Fulminans with Acute Kidney Injury, Due to Pneumococcal Sepsis in Children, Associated with Multiorgan Failure Open
Streptococcus pneumoniae is one of the associated bacteria that can cause the rare but high mortality hematological disease known as purpura fulminans (PF) in both adults and children. Patients with PF can progress quickly to sepsis and mu…
View article: Remdesivir Efficacy and Tolerability in Children with COVID-19-Associated Allergic Comorbidities such as Asthma, Allergic Rhinitis, and Atopic Dermatitis
Remdesivir Efficacy and Tolerability in Children with COVID-19-Associated Allergic Comorbidities such as Asthma, Allergic Rhinitis, and Atopic Dermatitis Open
In children, coronavirus disease 2019 (COVID-19) starts as a minor illness compared to adults, but during the ongoing COVID-19 pandemic, distinct SARS-CoV-2 variants and subvariants have changed options for therapies in both adults and chi…
View article: Vaccination and Factors Related to the Clinical Outcome of COVID-19 in Healthcare Workers—A Romanian Front-Line Hospital’s Experience
Vaccination and Factors Related to the Clinical Outcome of COVID-19 in Healthcare Workers—A Romanian Front-Line Hospital’s Experience Open
The study aims to describe the frequency of COVID-19 in healthcare workers (HCWs) in a designated hospital for COVID-19 treatment in Bucharest, Romania, and to explore COVID-19 vaccination and other factors associated with the clinical out…
View article: Features of respiratory syncytial virus infection in children in the post-COVID-19 era
Features of respiratory syncytial virus infection in children in the post-COVID-19 era Open
Respiratory syncytial virus (RSV) infection in children is a major public health problem, especially in the 0-1 year age group where clinical forms of the disease can evolve severely with life-threatening complications. In the period 2020 …
View article: Sepsis with Staphylococcus aureus in child with selective IgA deficiency and SARS-CoV-2 infection - case presentation
Sepsis with Staphylococcus aureus in child with selective IgA deficiency and SARS-CoV-2 infection - case presentation Open
Sepsis is one of the most severe pediatric infectious diseases that can progress to serious complications or even death without specialized treatment. It often evolves as a complication of a viral illness or against the background of a dep…
View article: Zoonotic Infection with Rabies Virus Leading to Fatal Encephalitis in Pediatric Patient – Case Report
Zoonotic Infection with Rabies Virus Leading to Fatal Encephalitis in Pediatric Patient – Case Report Open
Rabies is a life-threatening and vaccine-preventable infectious disease and is triggered by an RNA virus, part of the Rhabdoviridae family, Lyssavirus genus. It is transmitted from infected saliva due to biting, but also from contact with …
View article: Liver fibrosis progression in a cohort of young HIV and HIV/ HBV co-infected patients: A longitudinal study using non-invasive APRI and Fib-4 scores
Liver fibrosis progression in a cohort of young HIV and HIV/ HBV co-infected patients: A longitudinal study using non-invasive APRI and Fib-4 scores Open
Background The risk of liver fibrosis increases over time in HIV and HIV-HBV individuals even under antiretroviral treatment (ART), warranting a rigorous and periodic monitorization. Given the lower availability of transient elastography, …
View article: Transient immune hepatitis as post-coronavirus disease complication: A case report
Transient immune hepatitis as post-coronavirus disease complication: A case report Open
Close attention should also be paid to young patients with mild forms of disease, and a high index of suspicion should be maintained for post-COVID complications.
View article: A severe case of COVID-19 in an adolescent with PIMS-TS, cardiomyopathy, and pulmonary embolism.
A severe case of COVID-19 in an adolescent with PIMS-TS, cardiomyopathy, and pulmonary embolism. Open
We report the case of a 14-year-old male patient with no previous history of cardiovascular disease or thromboembolic episodes, admitted to our hospital with a severe form of COVID-19, in the 9th day of disease evolution, with acute respir…
View article: Measles in Romania – clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic
Measles in Romania – clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic Open
A large measles epidemic has been ongoing in Romania and many European countries, since 2016. We report case-based surveillance data for all patients (n = 1371) with laboratory-confirmed and epidemiologically-confirmed measles hospitalized…
View article: The 2017–2018 influenza season in Bucharest, Romania: epidemiology and characteristics of hospital admissions for influenza-like illness
The 2017–2018 influenza season in Bucharest, Romania: epidemiology and characteristics of hospital admissions for influenza-like illness Open
View article: Presepsin - New Marker of Sepsis Romanian Neonatal Intensive Care Unit Experience
Presepsin - New Marker of Sepsis Romanian Neonatal Intensive Care Unit Experience Open
Difficulties in establishing the onset of neonatal sepsis has directed the medical research in recent years to the possibility of identifying early biological markers of diagnosis. Overdiagnosing neonatal sepsis leads to a higher rate and …
View article: GP70 Pulmonary miliary tuberculosis in a toddler after initial presentation with tuberculous meningitis
GP70 Pulmonary miliary tuberculosis in a toddler after initial presentation with tuberculous meningitis Open
Introduction Even though tuberculosis is considered to be a rare disease in developed countries, Romania is facing an important public health problem despite the fact that every newborn receives a BCG vaccine in maternity. Case report We r…
View article: GP45 Autoimmune encephalitis triggered by herpes simplex virus 1 infection
GP45 Autoimmune encephalitis triggered by herpes simplex virus 1 infection Open
Introduction Herpetic encephalitis is the most frequent central nervous system infection in children caused by viral etiology. It may be a trigger for anti-NMDA receptor (NMDAR) encephalitis with the onset of symptoms usually a few weeks a…
View article: Severe Modifications of Biological Markers in Late Neonatal Sepsis in a Very Low Birth Weight Due to Candida lusitaniae
Severe Modifications of Biological Markers in Late Neonatal Sepsis in a Very Low Birth Weight Due to Candida lusitaniae Open
Neonatal sepsis is a major cause of neonatal mortality and morbidity in preterm, very low birth weight infants. Coagulase-negative staphylococcus and Candida spp. are among the most common causes of single infections and coinfections in ne…
View article: Fetal Cerebral Monitoring During the Second Stage of Labor
Fetal Cerebral Monitoring During the Second Stage of Labor Open
The moment of perinatal hypoxic injury is still difficult to be identified by current monitoring techniques. Recent studies highlights that the effectiveness of therapy in hypoxic ischemic encephalopathy, such as therapeutic hypothermia an…
View article: Pneumococcal Colonization and Pneumococcal Disease in Children with Influenza Clinical, laboratory and epidemiological features
Pneumococcal Colonization and Pneumococcal Disease in Children with Influenza Clinical, laboratory and epidemiological features Open
We retrospectively studied clinical features of the 2015-2016 paediatric influenza season and the rate of pneumococcal colonization/disease in a reference Romanian infectious diseases institute. Peak influenza activity occurred between wee…
View article: Measles in perspective – lessons learned from the ongoing outbreak in Romania
Measles in perspective – lessons learned from the ongoing outbreak in Romania Open
View article: The influenza season 2016/17 in Bucharest, Romania – surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital
The influenza season 2016/17 in Bucharest, Romania – surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital Open
View article: Biochemical Modifications in HIV-Infected Children and Adolescents Under Antiretroviral Therapy
Biochemical Modifications in HIV-Infected Children and Adolescents Under Antiretroviral Therapy Open
In this paper we propose to present the biochemical modifications in children and adolescents with HIV infection/AIDS undergoing antiretroviral therapy (ART). We have carried out a retrospective study on 200 HIV-seropositive children regis…