Luna Slemann
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View article: Exploring the origins of frequent tau-PET signal in vermal and adjacent regions
Exploring the origins of frequent tau-PET signal in vermal and adjacent regions Open
Purpose Off-target binding remains a significant challenge in tau-PET neuroimaging. While off-targets including monoamine oxidase enzymes and neuromelanin-containing cells have been identified, recent studies indicated a relevant binding o…
View article: Tau deposition patterns are associated with functional connectivity in primary tauopathies
Tau deposition patterns are associated with functional connectivity in primary tauopathies Open
Tau pathology is the main driver of neuronal dysfunction in 4-repeat tauopathies, including cortico-basal degeneration and progressive supranuclear palsy. Tau is assumed to spread prion-like across connected neurons, but the mechanisms of …