Li Cai
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View article: Compound heterozygous low-density lipoprotein receptor variants causing homozygous of familial hypercholesterolemia in two sisters: a case report
Compound heterozygous low-density lipoprotein receptor variants causing homozygous of familial hypercholesterolemia in two sisters: a case report Open
This study underscores the critical importance of early diagnosis and treatment in HoFH and highlights the necessity for ongoing research into more effective therapeutic strategies. Through this report, we aim to deepen the understanding o…
View article: Association of prenatal exposure to ozone with childhood emotional and behavioral problems and the modification of polyunsaturated fatty acids: A birth cohort study
Association of prenatal exposure to ozone with childhood emotional and behavioral problems and the modification of polyunsaturated fatty acids: A birth cohort study Open
Prenatal ozone exposure was adversely associated with emotional and behavioral problems in children. Higher maternal n-3 PUFAs and lower n-6 PUFAs were associated with weaker ozone-related neuropsychological effects.
View article: Breastfeeding initiation and duration: links to physical, mental and behavioural health in US children aged 3–5 years
Breastfeeding initiation and duration: links to physical, mental and behavioural health in US children aged 3–5 years Open
Background Breastfeeding is a cornerstone of child health. We investigated the associations of any breastfeeding initiation and duration with physical, mental and behavioural health conditions among children aged 3–5 years in the USA. Meth…
View article: P-094 Blastocyst Quality Distribution and the Clinical Efficacy of Non-invasive Preimplantation Genetic Testing in Women of Advanced Maternal Age
P-094 Blastocyst Quality Distribution and the Clinical Efficacy of Non-invasive Preimplantation Genetic Testing in Women of Advanced Maternal Age Open
Study question Does non-invasive preimplantation genetic testing (niPGT) increase the ongoing pregnancy rate among women without good-grade blastocysts? Summary answer In women lacking good-grade blastocysts, embryo transfer based on niPGT…
View article: Seasonal and spatial variations of nutrients and environmental effects under anthropogenic influence in Daya Bay, China
Seasonal and spatial variations of nutrients and environmental effects under anthropogenic influence in Daya Bay, China Open
Nutrients are crucial factors for the growth of phytoplankton, and their biogeochemical processes directly impact marine biodiversity. In this study, based on two cruise observations in spring and summer of 2024, the seasonal and spatial v…
View article: Tracking Human Exposure to DPG and Its Derivatives: Wastewater and Urine Analysis in Guangzhou, China
Tracking Human Exposure to DPG and Its Derivatives: Wastewater and Urine Analysis in Guangzhou, China Open
Tire additives, extensively utilized as industrial raw materials, may enter aquatic environments through various pathways during production, usage, or disposal processes. Research has shown that these additives pose potential threats to hu…
View article: The use of statins are associated with an increased risk of new-onset diabetes in patients with hypertension and obstructive sleep apnoea, a longitudinal study
The use of statins are associated with an increased risk of new-onset diabetes in patients with hypertension and obstructive sleep apnoea, a longitudinal study Open
In patients with OSA and hypertension, continuous statins use increases the risk of diabetes and physicians should be vigilant about monitoring blood glucose levels when using statins in this patients.
View article: Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers
Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers Open
Background Aldosterone is the effector hormone in the renin angiotensin aldosterone system and existing data suggest aldosterone affect cognitive function. However, the relationship between plasma aldosterone concentration (PAC) and cognit…
View article: The Cross-Sectional Association Between Multimorbidity and Sleep Quality and Duration Among the Elderly Community Dwellers in Northwest China
The Cross-Sectional Association Between Multimorbidity and Sleep Quality and Duration Among the Elderly Community Dwellers in Northwest China Open
There is a significant association between multimorbidity and poor sleep quality in older community dwellers, which may provide clues for disease prevention.
View article: Association between obstructive sleep apnea and 24-h urine protein quantification in patients with hypertension
Association between obstructive sleep apnea and 24-h urine protein quantification in patients with hypertension Open
The association between obstructive sleep apnea (OSA) and proteinuria is undetermined, with few studies on hypertension, a high-risk group for renal impairment. Therefore, we aimed to explore whether OSA is an independent risk factor for p…
View article: 147P Racial bias in pretreatment MRI radiomics features to predict response to neoadjuvant systemic treatment in breast cancer: A multicenter study in China, Germany, and the US
147P Racial bias in pretreatment MRI radiomics features to predict response to neoadjuvant systemic treatment in breast cancer: A multicenter study in China, Germany, and the US Open
Machine learning with radiomics showed great potential to predict response to neoadjuvant systemic treatment (NAST) for breast cancer. However, performance across different ethnicities and potential racial bias remain unclear. We aimed to …
View article: Infant Formulas With Partially or Extensively Hydrolyzed Milk Proteins for the Prevention of Allergic Diseases: A Systematic Review and Meta-Analysis of Clinical Trials
Infant Formulas With Partially or Extensively Hydrolyzed Milk Proteins for the Prevention of Allergic Diseases: A Systematic Review and Meta-Analysis of Clinical Trials Open
Despite the widely recommended usage of partially hydrolyzed formula (PHF) or extensively hydrolyzed formula (EHF) of milk protein for preventing allergic diseases (ADs), clinical studies have been inconclusive regarding their efficacy com…
View article: The Associations of Prenatal Exposure to Fine Particulate Matter and Its Chemical Components with Allergic Rhinitis in Children and the Modification Effect of Polyunsaturated Fatty Acids: A Birth Cohort Study
The Associations of Prenatal Exposure to Fine Particulate Matter and Its Chemical Components with Allergic Rhinitis in Children and the Modification Effect of Polyunsaturated Fatty Acids: A Birth Cohort Study Open
Prenatal exposure to and its chemical components, particularly BC, was associated with AR/symptoms in early childhood. We highlight that PUFA biomarkers could modify the adverse effects of on respiratory allergy. https://doi.org/10.1289/…
View article: Policies and Practices Regarding Preparative Fasting for Contrast-Enhanced Computed Tomography: A Nationwide Survey
Policies and Practices Regarding Preparative Fasting for Contrast-Enhanced Computed Tomography: A Nationwide Survey Open
Objectives To evaluate current policies and practices regarding preparative fasting before contrast-enhanced computed tomography (CECT) and the knowledge and attitudes of radiology head nurses. Methods Radiology head nurses in 499 Chinese …
View article: Effect of COVID-19 infection on pregnant women in plateau regions
Effect of COVID-19 infection on pregnant women in plateau regions Open
Pregnant women are vulnerable to the adverse consequences of COVID-19 infection, and public health measures such as vaccination are needed to protect this population subgroup.
View article: Clinical implications of forkhead box M1, cyclooxygenase-2<i>,</i> and glucose-regulated protein 78 in breast invasive ductal carcinoma
Clinical implications of forkhead box M1, cyclooxygenase-2<i>,</i> and glucose-regulated protein 78 in breast invasive ductal carcinoma Open
Rehabilitation of lower limb amputation in developing countries is quite challenging. Though there are basic to highly advanced prostheses available in India, the set-up is still facing difficulties in developing countries. Prosthetic mana…
View article: Efficacy of Establishing Physician-Scientists Supporting Program In A Teaching Hospital: A Ten Year Retrospective Study Running title: Efficacy Of Establishing Physician-Scientists Supporting Program In A Teaching Hospital
Efficacy of Establishing Physician-Scientists Supporting Program In A Teaching Hospital: A Ten Year Retrospective Study Running title: Efficacy Of Establishing Physician-Scientists Supporting Program In A Teaching Hospital Open
Background To gain insight into how well the program supports young physician-scientists and offers recommendations to enhance the program’s quality after establishing our hospital supporting physician-scientists program for ten years. Met…
View article: Effect of high-fructose consumption in pregnancy on the bone growth of offspring rats
Effect of high-fructose consumption in pregnancy on the bone growth of offspring rats Open
Growing evidence suggests that bone health is programmed in early life. Maternal diet may influence the skeletal development of offspring. We aimed to determine the possible effects of high-fructose intake during pregnancy on different asp…
View article: Infant feeding practices and autism spectrum disorder in US children aged 2–5 years: the national survey of children’s health (NSCH) 2016–2020
Infant feeding practices and autism spectrum disorder in US children aged 2–5 years: the national survey of children’s health (NSCH) 2016–2020 Open
Objective To investigate the relationship between infant feeding practices and autism spectrum disorder (ASD) among children aged 2–5 years in the United States (US). Methods Data from the 2016–2020 National Survey of Children’s Health, a …
View article: Supplementary Material from Analysis of the Transcriptome: Regulation of Cancer Stemness in Breast Ductal Carcinoma <i>In Situ</i> by Vitamin D Compounds
Supplementary Material from Analysis of the Transcriptome: Regulation of Cancer Stemness in Breast Ductal Carcinoma <i>In Situ</i> by Vitamin D Compounds Open
Supplementary Tables S1, S2, and Figures S1, S2, S3, S4, S5