Luobing Wang
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View article: Shizhifang alleviates hyperuricemia -induced renal injury by inhibiting Drp1 and maintaining mitochondrial homeostasis in renal tubular epithelial cells
Shizhifang alleviates hyperuricemia -induced renal injury by inhibiting Drp1 and maintaining mitochondrial homeostasis in renal tubular epithelial cells Open
SZF mitigates HUA-induced renal injury by inhibiting Drp1-mediated mitochondrial fission and mitophagy, promoting mitochondrial fusion, and reducing oxidative stress. These findings reveal a novel mitochondrial mechanism for SZF's reno-pro…
View article: Gubentongluo decoction alleviates NLRP3 inflammasome in IgAN cell model
Gubentongluo decoction alleviates NLRP3 inflammasome in IgAN cell model Open
Immunoglobulin A nephropathy (IgAN), the most common primary renal disease, is characterized by abnormal IgA1 deposition. IgAN is caused by NOD-like receptor pyrin domain-containing-3 (NLRP3), which regulates innate immunity. Gubentongluo …
View article: A Clinical Randomized Controlled Trial: Moxibustion at Laogong Interval With Panax Notoginseng Promoted the Maturation of Arteriovenous Fistulae
A Clinical Randomized Controlled Trial: Moxibustion at Laogong Interval With Panax Notoginseng Promoted the Maturation of Arteriovenous Fistulae Open
Background: We aim to study the clinical effect of moxibustion at Laogong interval with Panax notoginseng on the short-term maturation and long-term patency of arteriovenous fistula. Methods: Seventy-four pre-dialysis uremic patients who r…
View article: Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway Open
Increasing uric acid (UA) could induce renal tubular epithelial cell (NRK‑52E) injury. However, the specific mechanism by which UA induces renal tubular epithelial cell injury remains unknown. It was hypothesized that UA induces renal tubu…