Luoxi Tan
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View article: Toxic Effects of Butanol in the Plane of the Cell Membrane
Toxic Effects of Butanol in the Plane of the Cell Membrane Open
Solvent toxicity limits n-butanol fermentation titer, increasing the cost and energy consumption for subsequent separation processes and making biobased production more expensive and energy-intensive than petrochemical approaches. A…
View article: Amphiphilic Co-Solvents Modulate the Structure of Membrane Domains
Amphiphilic Co-Solvents Modulate the Structure of Membrane Domains Open
Biofuels are an increasing part of the sustainable energy picture. This makes it a societal and economic imperative to optimize biofuel production. Mitigating the toxic effects of amphiphilic co-solvents is one way to improve the efficienc…
View article: Improved chemical and isotopic labeling of biomembranes in Bacillus subtilis by leveraging CRISPRi inhibition of beta-ketoacyl-ACP synthase (fabF)
Improved chemical and isotopic labeling of biomembranes in Bacillus subtilis by leveraging CRISPRi inhibition of beta-ketoacyl-ACP synthase (fabF) Open
Assessing the structure of living microbial cell membranes is a challenging analytical goal. The cell membrane is defined by its transverse structure, an approximately 5 nm-thick selectively permeable bilayer that serves many important cel…
View article: Modeling the partitioning of amphiphilic molecules and co-solvents in biomembranes
Modeling the partitioning of amphiphilic molecules and co-solvents in biomembranes Open
Amphiphilic co-solvents can have a significant impact on the structure, organization and physical properties of lipid bilayers. Describing the mutual impact of partitioning and induced structure changes is therefore a crucial consideration…
View article: Implementation of a self-consistent slab model of bilayer structure in the <i>SasView</i> suite
Implementation of a self-consistent slab model of bilayer structure in the <i>SasView</i> suite Open
Slab models are simple and useful structural descriptions which have long been used to describe lyotropic lamellar phases, such as lipid bilayers. Typically, slab models assume a midline symmetry and break a bilayer structure into three pi…
View article: Molecular origins of bulk viscosity in liquid water
Molecular origins of bulk viscosity in liquid water Open
The shear viscous response of water is closely associated with changes in network connectivity on the sub ps timescale. The bulk viscous response is shown here to be associated with local density fluctuations and rotational motion around 1…