Luqman Ogunjimi
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View article: Assessing adverse reactions in people living with epilepsy on levetiracetam
Assessing adverse reactions in people living with epilepsy on levetiracetam Open
Background: This study aimed to evaluate factors associated with adverse drug reaction (ADR) among people with epilepsy (PWE) on Levetiracetam (LEV) monotherapy. Method: This descriptive, cross-sectional study, utilized a total purposive s…
View article: Perceived Body Image and Anthropometry Among Students
Perceived Body Image and Anthropometry Among Students Open
Objectives Body image dissatisfaction and anthropometry-related issues are a growing public health concern in Nigeria, particularly among young adults. Tertiary students, including those in Nigerian university campuses, may be susceptible …
View article: Blood pressure profiles and correlates among young adults in South Western Nigeria: A cross-sectional study
Blood pressure profiles and correlates among young adults in South Western Nigeria: A cross-sectional study Open
Background:There is a growing concern about the prevalence of high blood pressure among young adults, but its epidemiological profile remains poorly explored.Objective: This cross-sectional study described the pattern of blood pressure and…
View article: <i>Xylopia parviflora</i> (A. Rich.) Benth. ameliorates motor and behavioral deficits against haloperidol-induced experimental Parkinson’s disease rats
<i>Xylopia parviflora</i> (A. Rich.) Benth. ameliorates motor and behavioral deficits against haloperidol-induced experimental Parkinson’s disease rats Open
Objectives This study investigated the impact of hydroethanolic leaf extract of Xylopia parviflora (XPE) on motor activities, behavioral deficits, dopamine levels, cytokine release, and oxidative radicals in rats treated with haloperidol. …
View article: <i>Bambusa vulgaris</i> Extract: A Potential Natural Biogenic Amine Neurotransmitters Modulator, COX-2 Inhibitor and Oxidative Species Suppressor for Managing Depression and Anxiety
<i>Bambusa vulgaris</i> Extract: A Potential Natural Biogenic Amine Neurotransmitters Modulator, COX-2 Inhibitor and Oxidative Species Suppressor for Managing Depression and Anxiety Open
Objective Literature reveals a significant deficiency in scientific investigations regarding the use of Bambusa vulgaris extract (BVE) for the treatment of neuropsychiatric disorders, particularly those characterized by anxiety and depress…
View article: Xylopia parviflora (A. rich.) benth. Mitigates anxiety behavior and chronic mild stress-induced depression-like behavior in mice: The involvement of biogenic amine neurotransmitters, cyclooxygenase-2 and stress biomarkers in its antidepressant activity
Xylopia parviflora (A. rich.) benth. Mitigates anxiety behavior and chronic mild stress-induced depression-like behavior in mice: The involvement of biogenic amine neurotransmitters, cyclooxygenase-2 and stress biomarkers in its antidepressant activity Open
Background: Xylopia parviflora is a novel botanical in Modern Chinese Medicine that contains bioactive constituents including alkaloids, flavonoids, and terpenoids, which are the pharmacologically active components in various Chinese herba…
View article: Prescription patterns and therapeutic gaps among persons with epilepsy in Southwestern Nigeria
Prescription patterns and therapeutic gaps among persons with epilepsy in Southwestern Nigeria Open
Introduction: Pharmacotherapy with antiseizure medications (ASMs) has been a cornerstone for achieving long-term remissions in persons with epilepsy (PWEs). This study aims to determine the prescription patterns and treatment gaps (TGs) am…
View article: Relationship between depression and sex steroid hormone among women with epilepsy
Relationship between depression and sex steroid hormone among women with epilepsy Open
Introduction Sex steroid hormones are emerging significant biomarkers of depression among Women with Epilepsy (WWE) with promising prognostic potential and therapeutic end point. Therefore, the study is aimed at exploring the association b…
View article: Bambusa vulgaris attenuates Haloperidol-induced motor deficit and non-Motor co-morbidity in rats through up-regulation of Dopamine transmission and mitigation of pro-inflammatory cytokines activities
Bambusa vulgaris attenuates Haloperidol-induced motor deficit and non-Motor co-morbidity in rats through up-regulation of Dopamine transmission and mitigation of pro-inflammatory cytokines activities Open
Background: Bamboo is a plant widely distributed in many parts of the world and grows in about 18 provinces in China. One of the species of the plant is Bambusa vulgaris. An ethnobotanical survey of the plant revealed its values in managin…
View article: Factors associated with frequency of fruit and vegetable consumption among selected sub-Saharan African populations: evidence from the Cardiovascular H3Africa Innovation Resource Project
Factors associated with frequency of fruit and vegetable consumption among selected sub-Saharan African populations: evidence from the Cardiovascular H3Africa Innovation Resource Project Open
Background Frequent fruit and vegetable consumption is considered a promising dietary behaviour that protects health. However, most existing studies about the factors associated with this phenomenon among Africans are based on single-count…
View article: Differential effects of carbamazepine and levetiracetam monotherapy on reproductive endocrine function in Nigerian women with epilepsy
Differential effects of carbamazepine and levetiracetam monotherapy on reproductive endocrine function in Nigerian women with epilepsy Open
The therapeutics implication of lower LH and testosterone levels in the LTC group compared to CZP group need to be explored.
View article: Effect of psychoactive substance use on academic activities and performance among undergraduates of University of Lagos
Effect of psychoactive substance use on academic activities and performance among undergraduates of University of Lagos Open
Background: The objective of this study was to assess the effect of psychoactive substance use on academic performance among university students of Lagos undergraduates. Methods: This is a descriptive cross-sectional study to assess psycho…
View article: Determinants of First‐Ever Stroke Severity in West Africans: Evidence From the SIREN Study
Determinants of First‐Ever Stroke Severity in West Africans: Evidence From the SIREN Study Open
Background Baseline stroke severity is probably partly responsible for poor stroke outcomes in sub‐Saharan Africa. However, there is a paucity of information on determinants of stroke severity among indigenous Africans. We sought to identi…
View article: ADVERSE DRUG REACTION IN PEOPLE WITH EPILPSY
ADVERSE DRUG REACTION IN PEOPLE WITH EPILPSY Open
OBJECTIVES: There is a need for early identification and intervention of Adverse Drug Reaction (ADR) to alleviate unacceptably growing burden, morbidity and mortality associated in People With Epilepsy (PWE). This study is aimed at identif…
View article: Fast food consumption habits among young people in south western Nigeria
Fast food consumption habits among young people in south western Nigeria Open
Objective: The study assessed the profile and factors associated with fast food consumption among young people in tertiary educational institutions in Ibadan, Nigeria.Materials and Methods: This was a cross-sectional study carried out amon…
View article: Determinants of quality of life in Nigerian female patients with epilepsy on carbamazepine and levetiracetam monotherapy
Determinants of quality of life in Nigerian female patients with epilepsy on carbamazepine and levetiracetam monotherapy Open
Background The study is aimed to identify the predictors of Quality of Life (QOL) in women with epilepsy (WWE) on carbamazepine (CBM) and levetiracetam (LTM) monotherapy. 100 WWE were recruited (50 each on CBM and LTM), after clinical diag…
View article: Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study
Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study Open
For the Twi, Yoruba and Hausa translations of the abstract see Supplementary Materials section.
View article: Carotid and Vertebral Atherosclerosis in West African Stroke Patients: Findings from the Stroke Investigative Research and Education Network.
Carotid and Vertebral Atherosclerosis in West African Stroke Patients: Findings from the Stroke Investigative Research and Education Network. Open
One off our stroke patients in our cohort had atherosclerotic plaques, with ischemic patients being twice as likely to have this burden compared to hemorrhagic patients, and carotid atherosclerosis being five times as frequent as vertebral…
View article: Electroencephalographic Correlates of Cognition among Nigerian Women with Epilepsy on Anti-epileptic Monotherapy
Electroencephalographic Correlates of Cognition among Nigerian Women with Epilepsy on Anti-epileptic Monotherapy Open
Background: The prospect of EEG as a potential biomarker for detecting a cognitive decline in those living with epilepsy has not been extensively studied.
Objective: To determine the relationship between electroencephalographic (EEG) chan…
View article: Cognitive dysfunction in Nigerian women with epilepsy on carbamazepine and levetiracetam monotherapy
Cognitive dysfunction in Nigerian women with epilepsy on carbamazepine and levetiracetam monotherapy Open
Background This study aims to identify the determinants of cognitive dysfunction and compare the effect of CPZ and LTC on cognition in WWE. Methods An observational study involving 87 consenting adult WWE aged between 16 and 40 years on LT…
View article: Factors associated with hypertension among stroke‐free indigenous Africans: Findings from the SIREN study
Factors associated with hypertension among stroke‐free indigenous Africans: Findings from the SIREN study Open
Hypertension is one of the most important risk factors for stroke and cardiovascular diseases (CVD) globally. Understanding risk factors for hypertension among individuals with matching characteristics with stroke patients may inform primo…
View article: Unraveling the risk factors for spontaneous intracerebral hemorrhage among West Africans
Unraveling the risk factors for spontaneous intracerebral hemorrhage among West Africans Open
Population-level control of the dominant factors will substantially mitigate the burden of sICH in West Africa.
Knowledge, attitudes and practices related to stroke in Ghana and Nigeria: A SIREN call to action Open
The major findings illustrate the fears, causes, chief problems, treatment, and recommendations related to stroke through the views of the participants, as well as recommendations for working effectively with the SIREN communities. Finding…
View article: Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study
Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study Open
Background It is crucial to assess genomic literacy related to stroke among Africans in preparation for the ethical, legal and societal implications of the genetic revolution which has begun in Africa. Objective To assess the knowledge, at…
View article: Gaps in Guidelines for the Management of Diabetes in Low- and Middle-Income Versus High-Income Countries—A Systematic Review
Gaps in Guidelines for the Management of Diabetes in Low- and Middle-Income Versus High-Income Countries—A Systematic Review Open
OBJECTIVE The extent to which diabetes (DM) practice guidelines, often based on evidence from high-income countries (HIC), can be implemented to improve outcomes in low- and middle-income countries (LMIC) is a critical challenge. We carrie…