Luting Zhang
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View article: Development of a prognostic risk model for predicting biochemical recurrence-free survival in patients with prostate cancer based on lysine acetylation
Development of a prognostic risk model for predicting biochemical recurrence-free survival in patients with prostate cancer based on lysine acetylation Open
Five BCR-free-related prognostic genes were identified as potential therapeutic targets. Additionally, a BCR-free-related prognostic risk model was developed, offering a robust tool for predicting BCR-free survival in patients with PCa.
View article: Construction of a risk prediction model for axillary lymph node metastasis in breast cancer based on gray-scale ultrasound and clinical pathological features
Construction of a risk prediction model for axillary lymph node metastasis in breast cancer based on gray-scale ultrasound and clinical pathological features Open
Purpose This study aimed to develop a model to predict the risk of axillary lymph node (ALN) metastasis in breast cancer patients, using gray-scale ultrasound and clinical pathological features. Methods A retrospective analysis of 212 brea…
View article: Corrigendum: Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses
Corrigendum: Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses Open
[This corrects the article DOI: 10.3389/fgene.2022.974357.].
View article: Effects of HAR1 on cognitive function in mice and the regulatory network of HAR1 determined by RNA sequencing and applied bioinformatics analysis
Effects of HAR1 on cognitive function in mice and the regulatory network of HAR1 determined by RNA sequencing and applied bioinformatics analysis Open
Background: HAR1 is a 118-bp segment that lies in a pair of novel non-coding RNA genes. It shows a dramatic accelerated change with an estimated 18 substitutions in the human lineage since the human–chimpanzee ancestor, compared with the e…
View article: Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses
Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses Open
Objective: N 6 -methyladenosine (m 6 A) is a common post-transcriptional modification of messenger RNAs (mRNAs) and long non-coding RNAs (lncRNAs). However, m 6 A-modified lncRNAs are still largely unexplored. This study aimed to investiga…
View article: Integration of epigenomic and transcriptome analyses of neural tube defects reveals methylation driver lncRNAs and mRNAs
Integration of epigenomic and transcriptome analyses of neural tube defects reveals methylation driver lncRNAs and mRNAs Open
Background Abnormal genome-wide methylation during embryogenesis is associated with neural tube defects (NTDs) at birth. Long noncoding RNAs (lncRNAs) may be promising biomarkers for nervous system-related diseases. Therefore, we aimed to …
View article: Effects of oral tauroursodeoxycholic acid and/or intestinal probiotics on serum biochemical indexes and bile composition in patients with cholecystolithiasis
Effects of oral tauroursodeoxycholic acid and/or intestinal probiotics on serum biochemical indexes and bile composition in patients with cholecystolithiasis Open
Background: In recent years, gallstones have become a major condition affecting people’s health. Cholecystectomy remains an effective treatment method, but it has large risk factors. It is well known that the hepatoenteric axis plays a key…
View article: Widespread bacterial responses and their mechanism of bacterial metallogenic detoxification under high concentrations of heavy metals
Widespread bacterial responses and their mechanism of bacterial metallogenic detoxification under high concentrations of heavy metals Open
Microbial mineralization is increasingly used in bioremediation of heavy metal pollution, but better mechanistic understanding of the processes involved and how they are regulated are required to improve the practical application of microo…
View article: Integration of epigenomic and transcriptome analyses of neural tube defects reveals methylation driver lncRNAs and mRNAs
Integration of epigenomic and transcriptome analyses of neural tube defects reveals methylation driver lncRNAs and mRNAs Open
Background: Abnormal genome-wide methylation during embryogenesis is associated with neural tube defects (NTDs) at birth. Long noncoding RNAs (lncRNAs) may be promising biomarkers for nervous system-related diseases. Therefore, we aimed to…
View article: Identify the regulatory network of LncRNA HAR1A in neurological development by RNA-Sequencing and bioinformatics analysis.
Identify the regulatory network of LncRNA HAR1A in neurological development by RNA-Sequencing and bioinformatics analysis. Open
Background: LncRNA HAR1A, which is explicitly expressed in Cajal-Retzius neurons (CRs), has been reported to be related to the development of the human brain. As one of the human accelerated regions (HARs) gene, it plays an important role …
View article: An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia
An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia Open
View article: An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia
An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia Open