Lin Xie
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View article: Effect of early physical rehabilitation on the incidence of delirium in ICU patients with severe neurotrauma
Effect of early physical rehabilitation on the incidence of delirium in ICU patients with severe neurotrauma Open
View article: Prevalence and genetic characterization of diarrhea viruses among cattle in Guangdong, China
Prevalence and genetic characterization of diarrhea viruses among cattle in Guangdong, China Open
Background Bovine coronavirus (BCoV), bovine norovirus (BNoV), and bovine rotavirus C (BRVC) are common diarrheal viruses in cattle and pose significant threats to herds and humans. In this study, we collected 194 fresh fecal samples from …
View article: Visualization analysis of poisoning-related research based on CiteSpace
Visualization analysis of poisoning-related research based on CiteSpace Open
Objective Summarize the current status, hotspots, and frontier trends in poisoning research over the past decade using CiteSpace software, and provide direction for future research in toxicology and public health. Methods Relevant literatu…
View article: Evaluating the effectiveness of six exercise interventions for low back pain: a systematic review and meta-analysis
Evaluating the effectiveness of six exercise interventions for low back pain: a systematic review and meta-analysis Open
View article: Trend analysis and prediction of disease burden of occupational carbon monoxide poisoning in China based on the past two decades
Trend analysis and prediction of disease burden of occupational carbon monoxide poisoning in China based on the past two decades Open
View article: A Study on the Factors Influencing the Happiness of Rural Elderly
A Study on the Factors Influencing the Happiness of Rural Elderly Open
This study aimed to investigate the relationship between social support and life satisfaction among 200 rural elderly individuals using the "Social Support Rating Scale" and the "Life Satisfaction Rating Scale." Through independent sample …
View article: Global, Regional, and National Burden of Low Back Pain
Global, Regional, and National Burden of Low Back Pain Open
Study Design. This was an observational study. Objective. Assessing the global burden of disease for low back pain (LBP) using the 2021 GBD (Global Burden of Disease) database. Summary of Background Data. LBP is a leading cause of workforc…
View article: Real-World Effectiveness of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists (OW GLP-1RAs) in Comparison with Dipeptidyl Peptidase-4 Inhibitors (DPP-4is) for Glycemic Control and Weight Outcomes in Type 2 Diabetes Mellitus (RELATE)
Real-World Effectiveness of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists (OW GLP-1RAs) in Comparison with Dipeptidyl Peptidase-4 Inhibitors (DPP-4is) for Glycemic Control and Weight Outcomes in Type 2 Diabetes Mellitus (RELATE) Open
View article: Analysis of relevant influencing factors for recurrent urinary tract infections in children: exploring predictive factors and intervention measures
Analysis of relevant influencing factors for recurrent urinary tract infections in children: exploring predictive factors and intervention measures Open
Urinary system malformation, constipation, anemia, decreased IgA and IgG levels are all identified as independent risk factors for recurrent UTIs in children, and urinary system malformation is a better predictor for recurrent UTIs in chil…
View article: Incidence of childhood cancer in Canada during the COVID-19 pandemic
Incidence of childhood cancer in Canada during the COVID-19 pandemic Open
We did not observe a statistically significant change in the incidence of childhood cancer, or in the proportion of children enrolling in a clinical trial, presenting with metastatic disease or who died early during the first 9 months of t…
View article: Comparison of incidence/occurrence of cardiovascular events between ponatinib vs bosutinib among patients with at least one prior line of tyrosine kinase inhibitors in chronic myeloid leukemia in a community setting in the United States
Comparison of incidence/occurrence of cardiovascular events between ponatinib vs bosutinib among patients with at least one prior line of tyrosine kinase inhibitors in chronic myeloid leukemia in a community setting in the United States Open
View article: 123. Treatment Patterns and Prevalence of Inappropriate and Suboptimal Antibiotic Use Among Females with Uncomplicated Urinary Tract Infection in the US
123. Treatment Patterns and Prevalence of Inappropriate and Suboptimal Antibiotic Use Among Females with Uncomplicated Urinary Tract Infection in the US Open
Background Urinary tract infections (UTIs) are the most common bacterial infection requiring medical care. Despite Infectious Diseases Society of America (IDSA) 2011 guidelines on antimicrobial agent selection and duration of therapy for u…
View article: Medical Resource Use and Costs of Treating Sickle Cell-related Vaso-occlusive Crisis Episodes: A Retrospective Claims Study
Medical Resource Use and Costs of Treating Sickle Cell-related Vaso-occlusive Crisis Episodes: A Retrospective Claims Study Open
Background: The study investigated the economic burden of vaso-occlusive crisis (VOC) among sickle cell disease (SCD) patients, through assessment of overall utilization and costs and costs per VOC episode (regarding the number of VOC epis…
View article: PIN42 COMPARISON OF ECONOMIC BURDEN AND RISK OF HOSPITALIZATION AMONG HIV PATIENTS WITH AND WITHOUT HEPATITIS B COINFECTION IN THE VETERANS HEALTH ADMINISTRATION POPULATION
PIN42 COMPARISON OF ECONOMIC BURDEN AND RISK OF HOSPITALIZATION AMONG HIV PATIENTS WITH AND WITHOUT HEPATITIS B COINFECTION IN THE VETERANS HEALTH ADMINISTRATION POPULATION Open
View article: Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United States
Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United States Open
The majority of CD patients prescribed UST were biologic experienced, and persistence was high over the 1-year follow-up. UST treatment initiation was associated with reductions in ER visits, inpatient stays, and steroid and other medicati…
View article: Evaluating the Effect of Standard of Care Treatment on Burden of Chronic Hepatitis B: A Retrospective Analysis of the United States Veterans Population
Evaluating the Effect of Standard of Care Treatment on Burden of Chronic Hepatitis B: A Retrospective Analysis of the United States Veterans Population Open
CHB is associated with considerable economic burden. We observed suboptimal persistence to NAs which decreased over time. Short-term savings could be generated for CHB-infected patients when they remain persistent to NAs.
View article: PDB100 EXAMINING THE TEMPORAL TRENDS IN HYPOGLYCEMIA EVENTS, TREATMENT ADHERENCE AND A1C IN PATIENTS WITH T2D IN THE US
PDB100 EXAMINING THE TEMPORAL TRENDS IN HYPOGLYCEMIA EVENTS, TREATMENT ADHERENCE AND A1C IN PATIENTS WITH T2D IN THE US Open
View article: Reduction in Hospital Readmission Rates Among Medicare Beneficiaries With Chronic Obstructive Pulmonary Disease: A Real-world Outcomes Study of Nebulized Bronchodilators
Reduction in Hospital Readmission Rates Among Medicare Beneficiaries With Chronic Obstructive Pulmonary Disease: A Real-world Outcomes Study of Nebulized Bronchodilators Open
Nebulized ARF users had lower 30-day readmission rates, greater COPD severity, and fewer comorbidities than nebulized SABA users. In this population, maintenance treatment with ARF reduced costly COPD outcomes.
View article: Patients with Idiopathic Membranous Nephropathy: A Real-World Clinical and Economic Analysis of U.S. Claims Data
Patients with Idiopathic Membranous Nephropathy: A Real-World Clinical and Economic Analysis of U.S. Claims Data Open
This study was funded by Mallinckrodt Pharmaceuticals. Kirkemo, Pavlova-Wolf, and Bartels-Peculis are employees and stockholders of Mallinckrodt Pharmaceuticals. Nazareth was an employee of Mallinckrodt Pharmaceuticals at the time of this …
View article: Sickle cell disease complications: Prevalence and resource utilization
Sickle cell disease complications: Prevalence and resource utilization Open
In summary, SCD and its related comorbidities and complications result in high acute health care utilization. In addition, VOC remains the primary reason for SCD patients' ER visits and inpatient admissions.
View article: Hypoglycaemia and treatment patterns among insulin‐treated patients with type 2 diabetes who switched to insulin glargine 300 units/mL versus other basal insulin in a real‐world setting
Hypoglycaemia and treatment patterns among insulin‐treated patients with type 2 diabetes who switched to insulin glargine 300 units/mL versus other basal insulin in a real‐world setting Open
Introduction Type 2 diabetes (T2D) is characterized by worsening pancreatic β‐cell function often requiring treatment escalation with oral antidiabetic drugs ( OAD s), glucagon‐like peptide‐1 and eventually insulin. Although there is much …
View article: FRI0201 REAL WORLD MEDICATION USE IN INCIDENT SYSTEMIC LUPUS ERYTHEMATOSUS AND LUPUS NEPHRITIS PATIENTS
FRI0201 REAL WORLD MEDICATION USE IN INCIDENT SYSTEMIC LUPUS ERYTHEMATOSUS AND LUPUS NEPHRITIS PATIENTS Open
View article: Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study
Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study Open
Sickle cell disease (SCD) is a life-threatening vascular disease that burdens affected persons physically. SCD related vaso-occlusive crises (VOCs) are one of the primary causes of morbidity and mortality. Our objective was to examine the …
View article: Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study
Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study Open
Sickle cell disease (SCD) is a life-threatening vascular disease that burdens affected persons physically. SCD related vaso-occlusive crises (VOCs) are one of the primary causes of morbidity and mortality. Our objective was to examine the …
View article: Mo1909 – Evaluation of Health Care Utilization, Hospitalization/Emergency Room Costs, and Other Medication Use Among Crohn’s Disease Patients Using Ustekinumab in Three Large United States Commercial Claims Databases
Mo1909 – Evaluation of Health Care Utilization, Hospitalization/Emergency Room Costs, and Other Medication Use Among Crohn’s Disease Patients Using Ustekinumab in Three Large United States Commercial Claims Databases Open
View article: Sickle cell disease complications: prevalence and resource utilization
Sickle cell disease complications: prevalence and resource utilization Open
This study evaluated the prevalence rate of vaso-occlusive crisis (VOC) episodes, rates of uncomplicated and complicated VOC episodes, and the primary reasons for emergency room (ER) visits and inpatient admissions for sickle cell disease …
View article: COPD and the risk of mild cognitive impairment and dementia: a cohort study based on the Chinese Longitudinal Health Longevity Survey
COPD and the risk of mild cognitive impairment and dementia: a cohort study based on the Chinese Longitudinal Health Longevity Survey Open
Fei Xie, Lixin Xie Department of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing 100853, China Background: COPD may lead to cognitive impairment or even dementia. However, the current conclusions are inconsisten…
View article: A descriptive analysis of real-world treatment patterns of innovator (Remicade<sup>&reg;</sup>) and biosimilar infliximab in an infliximab-na&iuml;ve Turkish population
A descriptive analysis of real-world treatment patterns of innovator (Remicade<sup>®</sup>) and biosimilar infliximab in an infliximab-naïve Turkish population Open
In this population-based study, more IFX-naïve RA and IBD patients were initially treated with IFX than CT-P13. Discontinuation and switching were observed more often and earlier among patients treated with CT-P13 regardless of disease sta…
View article: PCN267 - HEALTHCARE UTILIZATION AND ECONOMIC BURDEN ON PATIENTS WITH BLADDER CANCER IN THE US DEPARTMENT OF DEFENSE POPULATION
PCN267 - HEALTHCARE UTILIZATION AND ECONOMIC BURDEN ON PATIENTS WITH BLADDER CANCER IN THE US DEPARTMENT OF DEFENSE POPULATION Open
View article: Observation versus treatment among men with favorable risk prostate cancer in a community-based integrated health care system: a retrospective cohort study
Observation versus treatment among men with favorable risk prostate cancer in a community-based integrated health care system: a retrospective cohort study Open
Use of OBS management increased over the 10-year study period. Men in the OBS cohort had a higher proportion of low-risk PCa. No differences were observed in overall survival between the two groups after adjustment of covariates. These dat…