Luyun Zhang
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View article: Impact of Ozone Exposure on Oral Microbiome: A Controlled, Randomized, Crossover Trial
Impact of Ozone Exposure on Oral Microbiome: A Controlled, Randomized, Crossover Trial Open
View article: Traditional Chinese Medicine Combined with Peginterferon α-2b in Chronic Hepatitis B: A Real-world Cohort Study
Traditional Chinese Medicine Combined with Peginterferon α-2b in Chronic Hepatitis B: A Real-world Cohort Study Open
View article: A USA Airline Business Traveler Loyalty Model: Cost-Effective Approaches to Enhance Customer Retention
A USA Airline Business Traveler Loyalty Model: Cost-Effective Approaches to Enhance Customer Retention Open
The airline industry remains highly competitive, making customer loyalty a crucial factor for maintaining profitability and ensuring long-term success. This research aims to uncover how airlines can strategically optimize their services to…
View article: Comparative efficacy and safety of pegylated interferon-alpha monotherapy vs combination therapies with entecavir or tenofovir in chronic hepatitis B patients
Comparative efficacy and safety of pegylated interferon-alpha monotherapy vs combination therapies with entecavir or tenofovir in chronic hepatitis B patients Open
Current treatments for chronic hepatitis B (CHB) virus involve nucleos(t)ide analogs and pegylated interferon-alpha (PEG-IFNα). This study compares the efficacy and safety of PEG-IFNα monotherapy with its combinations with entecavir (ETV) …
View article: Effects of Different Antiviral Treatments on Liver Inflammation and Fibrosis in Patients With Chronic Hepatitis B
Effects of Different Antiviral Treatments on Liver Inflammation and Fibrosis in Patients With Chronic Hepatitis B Open
Oral nucleotide analogues (NAs) and peginterferon‐α injections are commonly used for the treatment of patients with chronic hepatitis B (CHB). This study aims to evaluate the effects of different antiviral therapies on the degree of liver …
View article: A Clustering–Connection Algorithm for Coarse Root System Architecture Reconstruction Based on Ground-Penetrating Radar
A Clustering–Connection Algorithm for Coarse Root System Architecture Reconstruction Based on Ground-Penetrating Radar Open
Root system architecture (RSA), a critical attribute of plant roots, necessitates in situ reconstruction to advance the understanding of the subsurface plant root system. Ground Penetrating Radar (GPR), a non-invasive geophysical technique…
View article: Effects of trigger-day progesterone in c-IVF/ICSI cycles on blastocyst culture outcomes
Effects of trigger-day progesterone in c-IVF/ICSI cycles on blastocyst culture outcomes Open
Objective To assess whether trigger-day progesterone (P) levels in conventional in vitro fertilization (c-IVF)/intracytoplasmic sperm injection (ICSI) cycles are associated with blastocyst culture outcomes. Methods In this retrospective an…
View article: Integrated Extraction of Root Diameter and Location in Ground-Penetrating Radar Images via CycleGAN-Guided Multi-Task Neural Network
Integrated Extraction of Root Diameter and Location in Ground-Penetrating Radar Images via CycleGAN-Guided Multi-Task Neural Network Open
The diameter of roots is pivotal for studying subsurface root structure geometry. Yet, directly obtaining these parameters is challenging due their hidden nature. Ground-penetrating radar (GPR) offers a reproducible, nondestructive method …
View article: Two-dimensional Health State Map to define metabolic health using separated static and dynamic homeostasis features: a proof-of-concept study
Two-dimensional Health State Map to define metabolic health using separated static and dynamic homeostasis features: a proof-of-concept study Open
Defining metabolic health is critical for the earlier reversing of metabolic dysfunction and disease, and fasting-based diagnosis may not adequately assess an individual's metabolic adaptivity under stress. We constructed a novel Health St…
View article: <scp>RNA m6A</scp> methylation regulatory mechanism of resveratrol in premature senescence cells
<span>RNA m6A</span> methylation regulatory mechanism of resveratrol in premature senescence cells Open
Resveratrol, a natural compound found in various plants, is known for its anti‐inflammatory, antioxidant, and senescence‐delaying properties. RNA N6‐methyladenosine (m6A) methylation plays a crucial role in oxidative stress and premature c…
View article: Editorial: Immunometabolism and tumor microenvironment in hepatocellular carcinoma
Editorial: Immunometabolism and tumor microenvironment in hepatocellular carcinoma Open
View article: A Comprehensive Review of Traditional Medicinal Uses, Geographical Distribution, Botanical Characterization, Phytochemistry, and Pharmacology of Aralia continentalis Kitag.
A Comprehensive Review of Traditional Medicinal Uses, Geographical Distribution, Botanical Characterization, Phytochemistry, and Pharmacology of Aralia continentalis Kitag. Open
Aralia continentalis Kitag. (A. continentalis) holds significant medicinal value among the Aralia genus. It has traditionally been employed in ethnomedicine to address a wide range of conditions, including wind–cold–dampness arthralgia; rh…
View article: N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine induces endothelium-dependent hyperpolarization-mediated vasorelaxation via store-operated calcium entry mechanism in healthy and intestinal inflammatory mice
N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine induces endothelium-dependent hyperpolarization-mediated vasorelaxation via store-operated calcium entry mechanism in healthy and intestinal inflammatory mice Open
View article: Assessing the impact of COVID-19 inactivated vaccination doses on male fertility i n assisted insemination with husband's sperm (AIH) cycle
Assessing the impact of COVID-19 inactivated vaccination doses on male fertility i n assisted insemination with husband's sperm (AIH) cycle Open
Purpose This study aimed to assess the impact of coronavirus disease 2019 (COVID-19) inactivated vaccination doses on male fertility. Methods A retrospective cohort study was conducted, including 595 assisted insemination with husband's sp…
View article: Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis
Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis Open
View article: Diagnostic Efficacy of Vibration‐Controlled Transient Elastography in Patients With Metabolic Dysfunction–Associated Liver Disease and Chronic Hepatitis B
Diagnostic Efficacy of Vibration‐Controlled Transient Elastography in Patients With Metabolic Dysfunction–Associated Liver Disease and Chronic Hepatitis B Open
Aim of the Study: HBV‐infected individuals are also presenting with MASLD. However, the value of VCTE for detecting hepatic fibrosis and steatosis in CHB patients concurrent with MASLD is unclear. In patients with combined CHB and MASLD, w…
View article: Spatial–temporal characteristics of geological disaster resilience in poverty and disaster-prone areas in China: a case study of Ganzi Prefecture
Spatial–temporal characteristics of geological disaster resilience in poverty and disaster-prone areas in China: a case study of Ganzi Prefecture Open
Under the tremendous challenges of frequent disasters, disaster resilience is imperative for risk reduction and sustainable management in poverty and disaster-prone areas. Ganzi Prefecture has a complicated topography and vulnerable ecosys…
View article: Close association of PFASs exposure with hepatic fibrosis than steatosis: evidences from NHANES 2017–2018
Close association of PFASs exposure with hepatic fibrosis than steatosis: evidences from NHANES 2017–2018 Open
Multiple animals and in vitro studies have demonstrated that perfluoroalkyl and polyfluoroalkyl substances (PFASs) exposure causes liver damage associated with fat metabolism. However, it is lack of population evidence for the corre…
View article: Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice
Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice Open
Aim Sepsis is a life-threatening disease with high mortality worldwide. Septic females have lower severity and mortality than the males, suggesting estrogen exerts a protective action, but nothing is known about the role of vascular endoth…
View article: Association between perfluoroalkyl and polyfluoroalkyl internal exposure and serum α-Klotho levels in middle-old aged participants
Association between perfluoroalkyl and polyfluoroalkyl internal exposure and serum α-Klotho levels in middle-old aged participants Open
Purpose Exposure to perfluoroalkyl and polyfluoroalkyl substances causes oxidative stress, which is strongly associated with adverse health effects. Klotho protein plays an anti-aging role via antioxidation activity. Methods We investigate…
View article: Effects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial
Effects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial Open
National Health and Medical Research Council of Australia; UK Stroke Association; UK Dementia Research Institute; Ministry of Health and the National Council for Scientific and Technological Development of Brazil; Ministry for Health, Welf…
View article: The <scp>CaSR</scp>/<scp>TRPV4</scp> coupling mediates pro‐inflammatory macrophage function
The <span>CaSR</span>/<span>TRPV4</span> coupling mediates pro‐inflammatory macrophage function Open
Aim Although calcium‐sensing receptor (CaSR) and transient receptor potential vanilloid 4 (TRPV4) channels are functionally expressed on macrophages, it is unclear if they work coordinately to mediate macrophage function. The present study…
View article: Microscopic Modeling of Magnetorheological Fluids Containing Spherical and Ellipsoidal Ferromagnetic Particles
Microscopic Modeling of Magnetorheological Fluids Containing Spherical and Ellipsoidal Ferromagnetic Particles Open
View article: Synthesis and Biological Activity of Trolox Amide Derivatives
Synthesis and Biological Activity of Trolox Amide Derivatives Open
A series of Trolox amide derivatives were synthesized by modifying the carboxyl groups of Trolox. Thirty target compounds were obtained and characterized through nuclear magnetic resonance and mass spectrometry. Trolox derivatives were emp…
View article: Effects of Intensive Blood Pressure Lowering on Cerebral Ischaemia in Thrombolysed Patients: Insights from the Enchanted Trial
Effects of Intensive Blood Pressure Lowering on Cerebral Ischaemia in Thrombolysed Patients: Insights from the Enchanted Trial Open
View article: A Natural Monoterpene Enol for Dispersive Liquid–Liquid Microextraction Based on Solidification of Floating Organic Droplets for Determination of Benzophenone Compounds in Water Samples
A Natural Monoterpene Enol for Dispersive Liquid–Liquid Microextraction Based on Solidification of Floating Organic Droplets for Determination of Benzophenone Compounds in Water Samples Open
In the current study, an effective and simple procedure of extraction for the four benzophenone compounds from water samples was achieved by dispersive liquid–liquid microextraction (DLLME) based on the solidification of floating organic d…
View article: Empirical Analysis of Holiday Effect on Chinese Baijiu Stocks
Empirical Analysis of Holiday Effect on Chinese Baijiu Stocks Open
The baijiu sector is a representative segment of the Chinese stock market.In 1994, the first Baijiu stock "Shanxi Xinghuacun Fen Wine Factory" was successfully listed on Shanghai Stock Exchange.After that the segment faced rapid developmen…
View article: STUDY OF FACTORS INFLUENCING THE WALL SLIP OF A MAGNETORHEOLOGICAL FLUID
STUDY OF FACTORS INFLUENCING THE WALL SLIP OF A MAGNETORHEOLOGICAL FLUID Open
The wall slip of magnetorheological (MR) fluids refers to a phenomenon that affects the application of mechanical properties of magnetorheological fluids due to the relative slippage between the magnetic particles and the transmission wall…
View article: Epidemiological characteristics of community-acquired pneumonia and effects from the COVID-19 pandemic in Shenzhen of China
Epidemiological characteristics of community-acquired pneumonia and effects from the COVID-19 pandemic in Shenzhen of China Open
Objective This study aimed to observe the impact of the coronavirus disease 2019 (COVID-19) pandemic on the incidence of non-COVID-19 community-acquired pneumonia (CAP) in Shenzhen of China, offering new ideas for evaluating the effects of…
View article: Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress
Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress Open
Tripterygium glycoside tablet (TGT), as a common clinical drug, can easily cause liver damage due to the narrow therapeutic window. Glycyrrhizic acid (GA) has a hepatoprotective effect, but the characteristics and mechanism of GA’s impact …