Lv‐Hui Sun
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View article: Gut microbiome-derived indole-3-carboxaldehyde promotes intestinal development via AHR-NRF2 signaling in the early-life of chicks
Gut microbiome-derived indole-3-carboxaldehyde promotes intestinal development via AHR-NRF2 signaling in the early-life of chicks Open
Background The development of the small intestine is crucial during early life, with the gut microbiota and microbe-derived metabolites playing key roles in regulating intestinal epithelial barrier function and overall development. However…
View article: Validation with the Dynamic Prediction Model of Protein and Amino Acid Requirements for Growth Performance and Health in Layer Chicks
Validation with the Dynamic Prediction Model of Protein and Amino Acid Requirements for Growth Performance and Health in Layer Chicks Open
This study evaluated an established dynamic prediction model for protein and amino acid nutritional requirements on growth performance and health in layer chicks. A total of 288 one-day-old healthy Jing Tint 6 chicks were randomly divided …
View article: Dietary Supplementation of Zinc Oxide Quantum Dots Protective Against Clostridium perfringens Induced Negative Effects in Broilers
Dietary Supplementation of Zinc Oxide Quantum Dots Protective Against Clostridium perfringens Induced Negative Effects in Broilers Open
Clostridium perfringens is a major cause of necrotizing enteritis in chickens. This study aimed to investigate the effects of zinc oxide quantum dots (ZnO-QDs) on growth performance, redox status, and gut microbiota in broilers challenged …
View article: Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (Ovis aries)
Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (Ovis aries) Open
Yeast culture is widely used in ruminants to improve gut health, immunity, and productivity; however, its impact on meat quality remains unclear. This study aimed to investigate the effects of yeast culture supplementation in the basic die…
View article: Contamination of aflatoxin B1, deoxynivalenol and zearalenone in feeds in China from 2021 to 2024
Contamination of aflatoxin B1, deoxynivalenol and zearalenone in feeds in China from 2021 to 2024 Open
Background This study was carried out to investigate the individual and combined contamination of aflatoxin B 1 (AFB 1 ), deoxynivalenol (DON), and zearalenone (ZEN) in feeds in China between 2021 and 2024. A total of 23,003 feed samples, …
View article: Hydroxy-Selenomethionine Supplementation During Gestation and Lactation Improve Reproduction of Sows by Enhancing the Antioxidant Capacity and Immunity Under Heat Stress Conditions
Hydroxy-Selenomethionine Supplementation During Gestation and Lactation Improve Reproduction of Sows by Enhancing the Antioxidant Capacity and Immunity Under Heat Stress Conditions Open
The objective of this study was to determine whether hydroxy-selenomethionine (OH-SeMet) exerts better protective effects on sows against heat stress than sodium selenite (SeNa) or seleno-yeast (SeY). A total of 60 sows (Landrace × Yorkshi…
View article: Lactiplantibacillus plantarum JM113 alleviates mitochondrial dysfunction induced by deoxynivalenol in the jejunum of broiler chickens
Lactiplantibacillus plantarum JM113 alleviates mitochondrial dysfunction induced by deoxynivalenol in the jejunum of broiler chickens Open
Mitochondria are primary targets of deoxynivalenol (DON), which play a pivotal role in maintaining intestinal health. It has been suggested that Lactiplantibacillus plantarum JM113 (L. plantarum JM113) exhibits protective effects against t…
View article: SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus
SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus Open
Zinc (Zn) transporters contribute to the maintenance of intracellular Zn homeostasis in vertebrate, whose activity and function are modulated by post-translational modification. However, the function of small ubiquitin-like modifier (SUMOy…
View article: Alleviation of Lipid Disorder and Liver Damage in High-Fat Diet-Induced Obese Mice by Selenium-Enriched Cardamine violifolia with Cadmium Accumulation
Alleviation of Lipid Disorder and Liver Damage in High-Fat Diet-Induced Obese Mice by Selenium-Enriched Cardamine violifolia with Cadmium Accumulation Open
Background/Objectives: As a hyperaccumulator of selenium (Se), Cardamine violifolia (Cv) and its peptide extract could ameliorate the negative effects of a high-fat diet (HFD). However, the effects of the coaccumulation of cadmium (Cd) in …
View article: Loss of SELENOW aggravates muscle loss with regulation of protein synthesis and the ubiquitin-proteasome system
Loss of SELENOW aggravates muscle loss with regulation of protein synthesis and the ubiquitin-proteasome system Open
Sarcopenia is characterized by accelerated muscle mass and function loss, which burdens and challenges public health worldwide. Several studies indicated that selenium deficiency is associated with sarcopenia; however, the specific mechani…
View article: Effect of Dietary Sugarcane Bagasse on Reproductive Performance, Constipation, and Gut Microbiota of Gestational Sows
Effect of Dietary Sugarcane Bagasse on Reproductive Performance, Constipation, and Gut Microbiota of Gestational Sows Open
This experiment aimed to evaluate the effects of using sugarcane bagasse (SB) as a substitute for soybean hulls and wheat bran in the diet of pregnant sows on their reproductive performance and gut microbiota. A total of seventy-two primip…
View article: Polyacrylic Acid‐Coated Selenium‐Doped Carbon Dots Inhibit Ferroptosis to Alleviate Chemotherapy‐Associated Acute Kidney Injury
Polyacrylic Acid‐Coated Selenium‐Doped Carbon Dots Inhibit Ferroptosis to Alleviate Chemotherapy‐Associated Acute Kidney Injury Open
Cisplatin‐associated acute kidney injury (AKI) is a severe clinical syndrome that significantly restricts the chemotherapeutic application of cisplatin in cancer patients. Ferroptosis, a newly characterized programmed cell death driven by …
View article: Estimation of Protein and Amino Acid Requirements in Layer Chicks Depending on Dynamic Model
Estimation of Protein and Amino Acid Requirements in Layer Chicks Depending on Dynamic Model Open
Four trials were conducted to establish a protein and amino acid requirement model for layer chicks over 0–6 weeks by using the analytical factorization method. In trial 1, a total of 90 one-day-old Jing Tint 6 chicks with similar body wei…
View article: Tannic acid extracted from gallnut improves intestinal health with regulation of redox homeostasis and gut microbiota of weaned piglets
Tannic acid extracted from gallnut improves intestinal health with regulation of redox homeostasis and gut microbiota of weaned piglets Open
The objective of this study is to evaluate the effects of tannic acid (TA) derived from gallnut supplementation on growth performance and health status of weaned piglets. A total of 432 weanling piglets (7.05 ± 1.05 kg) were randomly alloc…
View article: Remediation Strategies for Mycotoxins in Animal Feed
Remediation Strategies for Mycotoxins in Animal Feed Open
Mycotoxins occur widely in various animal feedstuffs, with more than 500 mycotoxins identified so far [...]
View article: Selenium in modern agriculture
Selenium in modern agriculture Open
Selenium (Se) is a micronutrient necessary in small amounts for the proper organism functioning. Se‐rich agriculture, also known as special agriculture, has the potential to improve agricultural production and produce beneficial agricultur…
View article: Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787
Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787 Open
In the original publication [...]
View article: Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage
Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage Open
Aflatoxin B1 (AFB1) is amongst the mycotoxins commonly affecting human and animal health, raising global food safety and control concerns. The mechanisms underlying AFB1 toxicity are poorly understood. Moreover, antidotes against AFB1 are …
View article: Increased Ingestion of Hydroxy-Methionine by Both Sows and Piglets Improves the Ability of the Progeny to Counteract LPS-Induced Hepatic and Splenic Injury with Potential Regulation of TLR4 and NOD Signaling
Increased Ingestion of Hydroxy-Methionine by Both Sows and Piglets Improves the Ability of the Progeny to Counteract LPS-Induced Hepatic and Splenic Injury with Potential Regulation of TLR4 and NOD Signaling Open
Methionine, as an essential amino acid, play roles in antioxidant defense and the regulation of immune responses. This study was designed to determine the effects and mechanisms of increased consumption of methionine by sows and piglets on…
View article: Invited review: Remediation strategies for mycotoxin control in feed
Invited review: Remediation strategies for mycotoxin control in feed Open
Mycotoxins are secondary metabolites of different species of fungi. Aflatoxin B 1 (AFB 1 ), deoxynivalenol (DON), zearalenone (ZEN) and fumonisin B 1 (FB 1 ) are the main mycotoxins contaminating animal feedstuffs. These mycotoxins can pri…
View article: Organic Acids Improve Growth Performance with Potential Regulation of Redox Homeostasis, Immunity, and Microflora in Intestines of Weaned Piglets
Organic Acids Improve Growth Performance with Potential Regulation of Redox Homeostasis, Immunity, and Microflora in Intestines of Weaned Piglets Open
The objective of this study is to evaluate the effects of organic acids on piglet growth performance and health status. A total of 360 weanling pigs (5.3 ± 0.6 kg) were randomly allotted to 3 treatment groups with 12 replicates of 10 pigs/…
View article: Hydroxy-Selenomethionine Improves the Selenium Status and Helps to Maintain Broiler Performances under a High Stocking Density and Heat Stress Conditions through a Better Redox and Immune Response
Hydroxy-Selenomethionine Improves the Selenium Status and Helps to Maintain Broiler Performances under a High Stocking Density and Heat Stress Conditions through a Better Redox and Immune Response Open
This study has determined whether hydroxy-selenomethionine (OH-SeMet) exerts a better protective action on broilers against environmental stress than sodium selenite (SS) or seleno-yeast (SY). Day-old male Cobb 500 broilers (12 cages/diet,…