Madani Ly
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View article: Machine learning-assisted quantitative metabolomics of West African patients with advanced breast cancer
Machine learning-assisted quantitative metabolomics of West African patients with advanced breast cancer Open
In this study, we conducted a targeted quantitative metabolomic analysis of 630 metabolites in the plasma of 78 West African patients at the time of breast cancer diagnosis and prior to any treatment. Most of these patients were at an adva…
View article: Epidemio-Clinical, Anatomopathological, Computed Tomography Aspects from Breast Cancer to Imaging and Medical Oncology Departments at Chu – Mother-Child “Luxembourg”
Epidemio-Clinical, Anatomopathological, Computed Tomography Aspects from Breast Cancer to Imaging and Medical Oncology Departments at Chu – Mother-Child “Luxembourg” Open
Introduction: Cancer results from an anarchic proliferation of abnormal cells of the mammary gland and is the most common cancer in women in developed countries with 50,000 new cases in 2008. Objectives: The aim of our work was to describe…
View article: Prevalence of high-risk human papillomavirus genotypes in outpatient Malian women living with HIV: a pilot study
Prevalence of high-risk human papillomavirus genotypes in outpatient Malian women living with HIV: a pilot study Open
Introduction Long-term exposure to high-risk human papillomavirus (Hr-HPV) is a well-known necessary condition for development of cervical cancer. The aim of this study is to screen for Hr-HPV using vaginal self-sampling, which is a more e…
View article: Plasma 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Breast Cancer Risk in Mali: A Case–Control Study
Plasma 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Breast Cancer Risk in Mali: A Case–Control Study Open
(1) Background: Breast cancer is the most prevalent cancer found in women in Mali. The aim of the current study was to determine the association between metabolites circulating in the blood, 25(OH)D and 1,25(OH)2D, and vitamin D levels wit…
View article: Lack of Association of C677T Methylenetetrahydrofolate Reductase Polymorphism with Breast Cancer Risk in Mali
Lack of Association of C677T Methylenetetrahydrofolate Reductase Polymorphism with Breast Cancer Risk in Mali Open
Methylenetetrahydrofolate reductase (MTHFR) plays a major role in the metabolism of folates and homocysteine, which in turn can affect gene expression and ultimately promote the development of breast cancer. Thus, mutations in the MTHFR ge…
View article: Small Cell Lymphoma of the Gastrocnemius Muscle: A Case Report
Small Cell Lymphoma of the Gastrocnemius Muscle: A Case Report Open
Introduction: The primary localization of non-Hodgkin lymphoma of the muscle is rare. Only the biopsy allows the certainty diagnosis. The aim was to report a first case of small cell lymphoma of the gastrocnemius in Mali and to do a review…
View article: [Diagnosis and evaluation of the response to treatment of chronic myeloid leukaemia in Mali by fluorescent in situ hybridization].
[Diagnosis and evaluation of the response to treatment of chronic myeloid leukaemia in Mali by fluorescent in situ hybridization]. Open
We set up the FISH technique in Mali for the diagnosis and the follow-up of CML patients and identified atypical translocation of t(9;22).
View article: Relationships between gut microbiota, red meat consumption and colorectal cancer
Relationships between gut microbiota, red meat consumption and colorectal cancer Open
The temperature cooking of meat such as grilling and smoking contribute to the formation of mutagenic compounds including heterocyclic amines and polycyclic aromatic hydrocarbons. Heme iron in red meat is involved in the formation of N-nit…
View article: Factors associated with time to first healthcare visit, diagnosis and treatment, and their impact on survival among breast cancer patients in Mali
Factors associated with time to first healthcare visit, diagnosis and treatment, and their impact on survival among breast cancer patients in Mali Open
Down-staging strategies are only useful if the continuum of breast cancer care is warranted for the majority of patients.
View article: Intra-Arterial Delivery of Idarubicin in Two Patients with Glioblastoma
Intra-Arterial Delivery of Idarubicin in Two Patients with Glioblastoma Open
There is no effective treatment for recurrent glioblastoma (GB) when temozolomide-based radiochemotherapy fails. In theory, intra-arterial (IA) delivery of cytotoxic agents could achieve higher drug concentrations in tumors compared to int…