Lyle E. Wallis
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View article: Ultrasensitivity dynamics of diverse aryl hydrocarbon receptor modulators in a hepatoma cell line
Ultrasensitivity dynamics of diverse aryl hydrocarbon receptor modulators in a hepatoma cell line Open
The aryl hydrocarbon receptor (AhR) is a nuclear receptor that facilitates a wide transcriptional response and causes a variety of adaptive and maladaptive physiological functions. Such functions are entirely dependent on the type of ligan…
View article: A multimethod computational simulation approach for investigating mitochondrial dynamics and dysfunction in degenerative aging
A multimethod computational simulation approach for investigating mitochondrial dynamics and dysfunction in degenerative aging Open
Summary Research in biogerontology has largely focused on the complex relationship between mitochondrial dysfunction and biological aging. In particular, the mitochondrial free radical theory of aging ( MFRTA ) has been well accepted. Howe…