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Installing the “magic methyl” – C–H methylation in synthesis Open

Daniya Aynetdinova, Mia Callens, Harry B. Hicks, Charmaine Y. X. Poh, Benjamin D. A. Shennan , et al. · 2021

Following notable cases of remarkable potency increases in methylated analogues of lead compounds, this review documents the state-of-the-art in C–H methylation technology.