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View article: Sessile Serrated Lesions in Inflammatory Bowel Disease: Hidden Players in Colitis-Associated Colorectal Cancer?
Sessile Serrated Lesions in Inflammatory Bowel Disease: Hidden Players in Colitis-Associated Colorectal Cancer? Open
Sessile serrated lesions (SSLs) are well-known precursors of colorectal cancer in the general population, but their role in inflammatory bowel disease (IBD) is less clear. This narrative review summarizes what is known about the prevalence…
View article: When to Trust the Answer: Question-Aligned Semantic Nearest Neighbor Entropy for Safer Surgical VQA
When to Trust the Answer: Question-Aligned Semantic Nearest Neighbor Entropy for Safer Surgical VQA Open
Safety and reliability are essential for deploying Visual Question Answering (VQA) in surgery, where incorrect or ambiguous responses can harm the patient. Most surgical VQA research focuses on accuracy or linguistic quality while overlook…
View article: Septic Shock Due to Brevundimonas diminuta Bacteremia in an Immunocompetent Patient: A Case Report With a Literature Review of Antimicrobial Resistance Patterns
Septic Shock Due to Brevundimonas diminuta Bacteremia in an Immunocompetent Patient: A Case Report With a Literature Review of Antimicrobial Resistance Patterns Open
View article: Large language model for interpreting the Paris classification of colorectal polyps
Large language model for interpreting the Paris classification of colorectal polyps Open
Reporting of colorectal polyp morphology using the Paris classification is often inaccurate. Multimodal large language models (M-LLMs) may support morphological assessment. This study aimed to evaluate the accuracy of an M-LLM (GPT-4o) in …
View article: Outcomes of Endoscopic Resection of Circumferential Colorectal Laterally Spreading Lesions: A Western Experience
Outcomes of Endoscopic Resection of Circumferential Colorectal Laterally Spreading Lesions: A Western Experience Open
Background: Circumferential or near-circumferential colorectal lesions are challenging to remove endoscopically; therefore, they are often surgically managed. There are limited data on the outcomes of endoscopic submucosal dissection (ESD)…
View article: Following of Protocols for Chest Drain Insertion-an Audit Report
Following of Protocols for Chest Drain Insertion-an Audit Report Open
Background: Chest drain insertion is a common, potentially life-saving procedure indicated for conditions such as pneumothorax, hemothorax, and pleural effusion. Despite the availability of evidence-based guidelines from the British Thorac…
View article: Management of type I gastric-neuroendocrine tumors: the less the better?
Management of type I gastric-neuroendocrine tumors: the less the better? Open
Background and aims Type I gastric neuroendocrine tumors (gNETs) are known for their favorable prognosis. We aimed to present a real-life experience at a tertiary referral center. Materials and methods Retrospective analysis of patients di…
View article: STAndardization of Reports (the STAR project) Upper gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
STAndardization of Reports (the STAR project) Upper gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative Open
Upper gastrointestinal (UGI) endoscopy is the mainstay for the diagnosis and staging of precancerous and cancerous conditions of the esophagus, stomach, and duodenum. Despite development of several validated classifications for UGI disease…
View article: Analytical approach for identification and mechanistic insights into mRNA-lipid adduct formation
Analytical approach for identification and mechanistic insights into mRNA-lipid adduct formation Open
Messenger ribonucleic acid (mRNA), a promising tool in vaccine and therapeutic development, is reliant on intact mRNA delivery into target cells. Given its susceptibility to degradation, ensuring its stability is crucial, necessitating rig…
View article: Artificial Intelligence-Assisted Colonoscopy With or Without Mucosal Exposure Device for Detection of Colorectal Adenomas: A Meta-Analysis
Artificial Intelligence-Assisted Colonoscopy With or Without Mucosal Exposure Device for Detection of Colorectal Adenomas: A Meta-Analysis Open
Artificial intelligence (AI) and mucosal exposure devices like Endocuff have independently improved the adenoma detection rate (ADR) during colonoscopy. This meta-analysis evaluated the combined effect of Endocuff and AI versus AI alone on…
View article: Onion and Garlic Mixture Enhances Performance and Survival in Broiler Chickens Infected with Newcastle Disease Virus and Infectious Bronchitis Virus
Onion and Garlic Mixture Enhances Performance and Survival in Broiler Chickens Infected with Newcastle Disease Virus and Infectious Bronchitis Virus Open
Vaccines have become less effective due to more virulent antigens, prompting increased recommendations for natural herbs and phytochemicals. This study aimed to evaluate the effects of an onion and garlic mixture (OGM) on performance, carc…
View article: Adaptive surgical approach to giant inguinoscrotal hernia with enterocutaneous fistula in an adult paraplegic male with severe lordoscoliosis causing loss of domain: A case report and review of literature
Adaptive surgical approach to giant inguinoscrotal hernia with enterocutaneous fistula in an adult paraplegic male with severe lordoscoliosis causing loss of domain: A case report and review of literature Open
This is the first reported case of bilateral GIH with LOD in a paraplegic patient with severe scoliosis. The novel approach of scrotal repositioning offers a viable alternative when standard abdominal reintegration is unfeasible.
View article: Flushing ensures vessel presealing in underwater third-space endoscopy
Flushing ensures vessel presealing in underwater third-space endoscopy Open
View article: Collecting and Analyzing IBD Clinical Data for Machine-Learning: Insights from an Italian Cohort
Collecting and Analyzing IBD Clinical Data for Machine-Learning: Insights from an Italian Cohort Open
Research of Inflammatory Bowel Disease (IBD) involves integrating diverse and heterogeneous data sources, from clinical records to imaging and laboratory results, which presents significant challenges in data harmonization and exploration.…
View article: The Protective Effects of Ramadan Fasting against Cancer: Exploring Metabolic, Cellular, and Epigenetic Mechanisms
The Protective Effects of Ramadan Fasting against Cancer: Exploring Metabolic, Cellular, and Epigenetic Mechanisms Open
The practice of Ramadan fasting, as intermittent fasting, is growing in popularity because of its ability to prevent cancer development. The practice of fasting allows patients to experience multiple changes at metabolic, physiological, an…
View article: Prospective Comparison of Pathology and Computer-Aided Optical Diagnosis for Polyp Characterization using Expert Consensus
Prospective Comparison of Pathology and Computer-Aided Optical Diagnosis for Polyp Characterization using Expert Consensus Open
Background: Histopathology is the accepted gold standard for classifying colorectal polyps. However, the complex pathway from initial polyp detection and resection to final histological diagnosis involves multiple steps (retrieval, embeddi…
View article: Computer‐aided detection for esophageal achalasia (with video)
Computer‐aided detection for esophageal achalasia (with video) Open
Objectives Achalasia is an esophageal motility disorder that impairs quality of life and is often missed (20–50%) on endoscopy. A newly developed computer‐aided detection (CAD) software has shown high accuracy for achalasia diagnosis in pr…
View article: Diagnostic performance and agreement of auditors for evaluation of computer-aided optical polyp diagnosis: Prospective study
Diagnostic performance and agreement of auditors for evaluation of computer-aided optical polyp diagnosis: Prospective study Open
Guidelines recommend independent auditing of diagnostic performance for clinical implementation of computer-aided optical polyp diagnosis (CADx). This study evaluated diagnostic performance and interobserver agreement of auditors and offer…
View article: The Protective Effects of Ramadan Fasting against Cancer: Exploring Metabolic, Cellular, and Epigenetic Mechanisms
The Protective Effects of Ramadan Fasting against Cancer: Exploring Metabolic, Cellular, and Epigenetic Mechanisms Open
Fasting, particularly the fasting during Ramadan, is becoming very common due to the potential health benefits of which it is inclusive of its anti-cancer properties as well as therapy. It is mentioned in a recent study that intermittent f…
View article: Computer-aided diagnosis of colorectal polyps: assisted or autonomous?
Computer-aided diagnosis of colorectal polyps: assisted or autonomous? Open
Computer-aided diagnosis (CADx) in colonoscopy aims to improve the accuracy of diagnosing small polyps; however, its integration into clinical practice remains challenging. Human-artificial intelligence (AI) collaboration, which is expecte…
View article: Leniolisib, a PI3Kδ Inhibitor, Improves Lymphoproliferative Disease in a Murine Model of Autoimmune Lymphoproliferative Syndrome
Leniolisib, a PI3Kδ Inhibitor, Improves Lymphoproliferative Disease in a Murine Model of Autoimmune Lymphoproliferative Syndrome Open
Introduction Autoimmune lymphoproliferative syndrome (ALPS) is an inborn error of immunity characterized by lymphadenopathy, splenomegaly, autoimmune cytopenias, and an increased number of double-negative T cells (DNTs). ALPS is most often…
View article: Response to comment on "PuraStat for gastrointestinal bleeding management: Effective approach for endoscopic prevention and rescue therapy"
Response to comment on "PuraStat for gastrointestinal bleeding management: Effective approach for endoscopic prevention and rescue therapy" Open
View article: Ex vivo evaluation of a novel through-the-scope traction device for endoscopic submucosal dissection
Ex vivo evaluation of a novel through-the-scope traction device for endoscopic submucosal dissection Open
Endoscopic submucosal dissection (ESD) is a technique used for resection of large neoplastic lesions, providing great oncological outcomes. However, ESD is technically challenging with a long learning curve, high complication rates, and ex…
View article: Response to comment on “Endoscopic submucosal dissection for proximal colonic lesions: an effective therapeutic option”
Response to comment on “Endoscopic submucosal dissection for proximal colonic lesions: an effective therapeutic option” Open
View article: Exploring ChatGPT effectiveness in addressing direct patient queries on colorectal cancer screening
Exploring ChatGPT effectiveness in addressing direct patient queries on colorectal cancer screening Open
Recent studies showed that large language models (LLMs) could enhance understanding of colorectal cancer (CRC) screening, potentially increasing participation rates. However, a limitation of these studies is that questions posed to LLMs ar…
View article: Endoscopic Sustainability PrimAry Reporting Essentials (E-SPARE): European Society of Gastrointestinal Endoscopy (ESGE) Position Statement
Endoscopic Sustainability PrimAry Reporting Essentials (E-SPARE): European Society of Gastrointestinal Endoscopy (ESGE) Position Statement Open
A growing number of studies aim to evaluate gastrointestinal (GI) endoscopy services from the perspective of their environmental impact. However, there are currently no guidelines or frameworks which provide specifically for the reporting …
View article: Flushing ensures vessel presealing in underwater third-space endoscopy
Flushing ensures vessel presealing in underwater third-space endoscopy Open
International audience
View article: Benefits, burden, and harms of computer aided polyp detection with artificial intelligence in colorectal cancer screening: microsimulation modelling study
Benefits, burden, and harms of computer aided polyp detection with artificial intelligence in colorectal cancer screening: microsimulation modelling study Open
Objective To estimate the benefits, burden, and harms of implementing computer aided detection (CADe) of polyps in colonoscopy of population based screening programmes for colorectal cancer. Design Microsimulation modelling study. Setting …
View article: AI and Polyp Detection During Colonoscopy
AI and Polyp Detection During Colonoscopy Open
Colorectal cancer (CRC) prevention depends on effective colonoscopy; yet variability in adenoma detection rates (ADRs) and missed lesions remain significant hurdles. Artificial intelligence-powered computer-aided detection (CADe) systems o…
View article: Revolutionizing MASLD: How Artificial Intelligence Is Shaping the Future of Liver Care
Revolutionizing MASLD: How Artificial Intelligence Is Shaping the Future of Liver Care Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is emerging as a leading cause of chronic liver disease. In recent years, artificial intelligence (AI) has attracted significant attention in healthcare, particularly in diag…