David M. Levine
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View article: Bringing heart care home: management of acute cardiovascular pathologies in the Home Hospital
Bringing heart care home: management of acute cardiovascular pathologies in the Home Hospital Open
The Home Hospital (HH) model delivers hospital-level acute care in patients’ homes, offering a scalable, patient-centred alternative to traditional brick-and-mortar facilities. By integrating multidisciplinary teams, remote monitoring, and…
View article: Practice Standards for Acute Hospital Care at Home
Practice Standards for Acute Hospital Care at Home Open
Background Hospital at home (HaH) provides hospital‐level care at home as a substitute for brick‐and‐mortar hospital care. Multiple HaH studies demonstrate HaH provides safe, high‐quality, cost‐effective care. However, practices have varie…
View article: The role of continuous monitoring in acute-care settings for predicting all-cause 30-day hospital readmission: A pilot study
The role of continuous monitoring in acute-care settings for predicting all-cause 30-day hospital readmission: A pilot study Open
The systematic ML modeling and analysis showcased diversity in predictive power and performances of patient data sources for predicting readmission. This pilot study suggests continuous vital signs and activity data, when added to episodic…
View article: PERSPECTIVES ON POLICIES TO IMPROVE EQUITY IN HOSPITAL AT HOME
PERSPECTIVES ON POLICIES TO IMPROVE EQUITY IN HOSPITAL AT HOME Open
Hospital at Home (HaH) delivers acute hospital-level care at home as a substitute for traditional hospital care. Compared to traditional hospital care, HaH care demonstrates better patient satisfaction and care experience, lower readmissio…
View article: Hospital at home worldwide: Program and clinician characteristics from the World Hospital at Home Congress survey
Hospital at home worldwide: Program and clinician characteristics from the World Hospital at Home Congress survey Open
Background Hospital at home (HaH) delivers hospital‐level care to acutely ill patients at home as a substitute for brick‐and‐mortar hospital care. The clinician and program characteristics of HaH programs worldwide are relatively unknown. …
View article: The diagnostic and triage accuracy of the GPT-3 artificial intelligence model: an observational study
The diagnostic and triage accuracy of the GPT-3 artificial intelligence model: an observational study Open
The National Heart, Lung, and Blood Institute.
View article: Implementation of Agile in healthcare: methodology for a multisite home hospital accelerator
Implementation of Agile in healthcare: methodology for a multisite home hospital accelerator Open
Background The diffusion of innovation in healthcare is sluggish. Evidence-based care models and interventions take years to reach patients. We believe the healthcare community could deliver innovation to the bedside faster if it followed …
View article: Acute Hospital Care at Home in the United States: The Early National Experience
Acute Hospital Care at Home in the United States: The Early National Experience Open
Letters9 January 2024Acute Hospital Care at Home in the United States: The Early National ExperienceDavid M. Levine, MD, MPH, MA, Jeffrey Souza, MA, Jeffrey L. Schnipper, MD, MPH, Thomas C. Tsai, MD, MPH, Bruce Leff, MD, Bruce E. Landon, M…
View article: Automation of Functional Mobility Assessments at Home Using a Multimodal Sensor System Integrating Inertial Measurement Units and Computer Vision (IMU-Vision)
Automation of Functional Mobility Assessments at Home Using a Multimodal Sensor System Integrating Inertial Measurement Units and Computer Vision (IMU-Vision) Open
Objective Functional movement assessments are routinely used to evaluate and track changes in mobility. The objective of this study was to evaluate a multimodal movement monitoring system developed for autonomous, home-based, functional mo…
View article: Implementation of Agile in health care: Methodology for a multi-site home hospital accelerator
Implementation of Agile in health care: Methodology for a multi-site home hospital accelerator Open
Background The diffusion of innovation in health care is sluggish. Evidence-based care models and interventions take years to reach patients. We believe the health care community could deliver innovation to the bedside faster if it followe…
View article: Home hospital heart failure admissions are an opportunity to initiate goal directed medical therapy - a retrospective analysis
Home hospital heart failure admissions are an opportunity to initiate goal directed medical therapy - a retrospective analysis Open
Background There is growing recognition of the importance of goal directed medical therapy (GDMT) initiation for heart failure (HF) during hospitalization. Home hospital provides traditional inpatient hospital care in the patient’s home. D…
View article: Caregiver burden in a home hospital versus traditional hospital: A secondary analysis of a randomized controlled trial
Caregiver burden in a home hospital versus traditional hospital: A secondary analysis of a randomized controlled trial Open
Hospitals are standard of care for patients with acute illness, but hospitalization can result in heavy financial burden and iatrogenic risk, particularly in older populations. An alternative to inpatient care, "home hospital" provides acu…
View article: Single-lead arrhythmia detection through machine learning: cross-sectional evaluation of a novel algorithm using real-world data
Single-lead arrhythmia detection through machine learning: cross-sectional evaluation of a novel algorithm using real-world data Open
Background Computer-assisted interpretation of single-lead ECG is the preliminary method for clinicians to flag and further evaluate an arrhythmia of clinical importance for acutely ill patients. Critical scrutiny of novel detection algori…
View article: Data from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus
Data from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus Open
Background: Important risk factors for esophageal adenocarcinoma and its precursor, Barrett's esophagus, include gastroesophageal reflux disease, obesity, and cigarette smoking. Recently, genome-wide association studies have identified sev…
View article: Supplementary tables 1-6 from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus
Supplementary tables 1-6 from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus Open
Supplementary Table 1. Missing rates for three risk factors by study site in BEAGESS Supplementary Table 2. Genome-wide significant single nucleotide polymorphisms (SNPs) selected for GxE analysis. Supplementary Table 3. Odds ratios (95% c…
View article: Supplementary Figure legends from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus
Supplementary Figure legends from A Newly Identified Susceptibility Locus near <i>FOXP1</i> Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus Open
Figure legends
View article: Supplementary Table S1 from Pleiotropic Analysis of Cancer Risk Loci on Esophageal Adenocarcinoma Risk
Supplementary Table S1 from Pleiotropic Analysis of Cancer Risk Loci on Esophageal Adenocarcinoma Risk Open
Association between 387 SNPs and risk of EA, BE, or EA/BE combined
View article: Upper extremity deep venous thrombosis after BNT162b2 mRNA COVID‐19 vaccine case report
Upper extremity deep venous thrombosis after BNT162b2 mRNA COVID‐19 vaccine case report Open
We describe a case of an otherwise healthy 60‐year‐old female patient who presented 6 days after receipt of the second dose of the BNT162b2 mRNA COVID‐19 (Pfizer/BioNTech) vaccine and was found to have upper extremity deep venous thrombosi…
View article: The Diagnostic and Triage Accuracy of the GPT-3 Artificial Intelligence Model
The Diagnostic and Triage Accuracy of the GPT-3 Artificial Intelligence Model Open
Importance Artificial intelligence (AI) applications in health care have been effective in many areas of medicine, but they are often trained for a single task using labeled data, making deployment and generalizability challenging. Whether…
View article: The Safety of Inpatient Health Care
The Safety of Inpatient Health Care Open
Adverse events were identified in nearly one in four admissions, and approximately one fourth of the events were preventable. These findings underscore the importance of patient safety and the need for continuing improvement. (Funded by th…
View article: A Coke by Any Other Name: What New Coke Can Teach about Having Trust, Losing Trust, and Gaining It Back Again
A Coke by Any Other Name: What New Coke Can Teach about Having Trust, Losing Trust, and Gaining It Back Again Open
For 99 years, Coca-Cola sold itself as an American icon made with a secret recipe that was locked away in an Atlanta vault. Then, in 1985, in an attempt to compete with Pepsi-Cola, Coca-Cola changed the taste of Coke. After an uproar, the …
View article: A national qualitative study of Hospital‐at‐Home implementation under the <scp>CMS</scp> Acute Hospital Care at Home waiver
A national qualitative study of Hospital‐at‐Home implementation under the <span>CMS</span> Acute Hospital Care at Home waiver Open
Background The Centers for Medicare & Medicaid Services (CMS) announced the Acute Hospital Care at Home (AHCaH) waiver program in November 2020 to help expand hospital capacity to cope with the COVID‐19 pandemic. The AHCaH waived the 24/7 …
View article: Remote vs In-home Physician Visits for Hospital-Level Care at Home
Remote vs In-home Physician Visits for Hospital-Level Care at Home Open
ClinicalTrials.gov Identifier: NCT04080570.