Mary E. D’Alton
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View article: Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants
Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants Open
Importance The management of patent ductus arteriosus (PDA) in preterm infants is controversial. Objective To determine whether expectant management compared with active treatment of a protocol-defined PDA in preterm infants decreases the …
View article: Interpretation of the association between thyroid peroxidase antibodies and thyroid function during pregnancy: An individual participant data meta-analysis
Interpretation of the association between thyroid peroxidase antibodies and thyroid function during pregnancy: An individual participant data meta-analysis Open
During pregnancy, TPOAbs were dose-dependently associated with TSH, FT4, and the risk of abnormal thyroid function. With concentrations below currently used positivity cut-offs, TPOAbs could be associated with lower maternal thyroid functi…
View article: Implementation of a statewide bundle on obstetric hemorrhage in New York
Implementation of a statewide bundle on obstetric hemorrhage in New York Open
Introduction Obstetric hemorrhage is one of the leading causes of maternal death and also one of the most preventable. In 2017, a New York statewide initiative led by the New York State Perinatal Quality Collaborative asked birthing hospit…
View article: Radon Exposure and Gestational Diabetes
Radon Exposure and Gestational Diabetes Open
Importance Understanding environmental risk factors for gestational diabetes (GD) is crucial for developing preventive strategies and improving pregnancy outcomes. Objective To examine the association of county-level radon exposure with GD…
Intramuscular methylergonovine to decrease blood loss during cesarean delivery for twins: A triple‐blinded placebo‐controlled randomized trial Open
Objective Our objective was to evaluate whether prophylactic administration of intramuscular (IM) methylergonovine after cord clamping reduces blood loss during planned cesarean delivery (CD) of twin pregnancies. Method This single‐center …
View article: Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial
Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial Open
Importance Infants with neonatal opioid withdrawal syndrome (NOWS) cared for with the Eat, Sleep, Console (ESC) care approach receive less pharmacologic treatment and have shorter hospital stays compared to usual care with the Finnegan Neo…
View article: Defining Gestational Thyroid Dysfunction Through Modified Nonpregnancy Reference Intervals: An Individual Participant Meta-analysis
Defining Gestational Thyroid Dysfunction Through Modified Nonpregnancy Reference Intervals: An Individual Participant Meta-analysis Open
Background Establishing local trimester-specific reference intervals for gestational TSH and free T4 (FT4) is often not feasible, necessitating alternative strategies. We aimed to systematically quantify the diagnostic performance of stand…
Confronting Alzheimer’s Disease Risk in Women: A Feasibility Study of Memory Screening as Part of the Annual Gynecological Well-Woman Visit Open
Objective: Routine health care visits offer the opportunity to screen older adults for symptoms of Alzheimer's disease (AD). Many women see their gynecologist as their primary health care provider. Given this unique relationship, the Women…
B vitamin intakes modify the association between particulate air pollutants and incidence of all-cause dementia: Findings from the Women's Health Initiative Memory Study Open
Introduction: Particulate air pollutants may induce neurotoxicity by increasing homocysteine levels, which can be lowered by high B vitamin intakes. Therefore, we examined whether intakes of three B vitamins (folate, B12, and B6) modified …
Adherence to a MIND-Like Dietary Pattern, Long-Term Exposure to Fine Particulate Matter Air Pollution, and MRI-Based Measures of Brain Volume: The Women’s Health Initiative Memory Study-MRI Open
BACKGROUND: Previous studies suggest that certain dietary patterns and constituents may be beneficial to brain health. Airborne exposures to fine particulate matter [particulate matter with aerodynamic diameter ≤2.5 μm (PM2.5)] are neuroto…
View article: Influence of Eat, Sleep, and Console on Infants Pharmacologically Treated for Opioid Withdrawal
Influence of Eat, Sleep, and Console on Infants Pharmacologically Treated for Opioid Withdrawal Open
Importance The function-based eat, sleep, console (ESC) care approach substantially reduces the proportion of infants who receive pharmacologic treatment for neonatal opioid withdrawal syndrome (NOWS). This reduction has led to concerns fo…
View article: Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis Open
Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid function test …
View article: Trends in and outcomes of delivery hospitalizations with lupus and antiphospholipid syndrome
Trends in and outcomes of delivery hospitalizations with lupus and antiphospholipid syndrome Open
Objective To assess trends and outcomes associated with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) during US delivery hospitalizations. Study Design The National Inpatient Sample from 2000 to 2019 was used for t…
View article: TSH and FT4 Reference Interval Recommendations and Prevalence of Gestational Thyroid Dysfunction: Quantification of Current Diagnostic Approaches
TSH and FT4 Reference Interval Recommendations and Prevalence of Gestational Thyroid Dysfunction: Quantification of Current Diagnostic Approaches Open
Context Guidelines recommend use of population- and trimester-specific thyroid-stimulating hormone (TSH) and free thyroxine (FT4) reference intervals (RIs) in pregnancy. Since these are often unavailable, clinicians frequently rely on alte…
View article: Neonatal encephalopathy and hypoxic–ischemic encephalopathy: moving from controversy to consensus definitions and subclassification
Neonatal encephalopathy and hypoxic–ischemic encephalopathy: moving from controversy to consensus definitions and subclassification Open
Neonatal encephalopathy (NE) is a “clinical syndrome of disturbed neurologic function in the first week after birth in an infant born at or beyond 35 weeks of gestation, manifest by a subnormal level of consciousness or seizures, often acc…
Acquired Hemophilia A: A Rare, Acquired Coagulopathy in the Postpartum Setting Open
Postpartum hemorrhage (PPH) remains a leading cause of maternal morbidity. Pregnancy-associated acquired hemophilia A (AHA) caused by autoantibodies against factor VIII can present with recurrent episodes of postpartum bleeding. Case 1 A 5…
View article: Associations of Telomere Length and Change With Cognitive Decline Were Modified by Sex and Race: The REGARDS Study
Associations of Telomere Length and Change With Cognitive Decline Were Modified by Sex and Race: The REGARDS Study Open
Introduction We examined the associations of baseline telomere length (TL) and TL change with cognitive function over time in older US adults, as well as differences by sex and race. Methods A total of 1820 cognitively healthy individuals …
View article: Cesarean Delivery Trends Among Patients at Low Risk for Cesarean Delivery in the US, 2000-2019
Cesarean Delivery Trends Among Patients at Low Risk for Cesarean Delivery in the US, 2000-2019 Open
Importance Reducing rates of unnecessary cesarean deliveries is both a national and a global health objective. However, there are limited national US data on trends in indications for low-risk cesarean delivery. Objective To determine temp…
View article: Delivery trends and obstetric outcomes in patients with Fontan circulation
Delivery trends and obstetric outcomes in patients with Fontan circulation Open
The rates of deliveries of patients with Fontan palliation are increasing on a national level. These deliveries have higher risks of obstetrical complications and severe maternal morbidity. Additional national clinical data are necessary t…
View article: Continuation of psychiatric medications during pregnancy
Continuation of psychiatric medications during pregnancy Open
Background: While medications for anxiety and depression are commonly used in the United States, it is unclear to what degree they are continued during pregnancy.Methods: We used a large administrative database to determine whether psychia…
Folate, Vitamin B<sub>6</sub>, and Vitamin B<sub>12</sub>Status in Association With Metabolic Syndrome Incidence Open
Importance The associations of B vitamin status with metabolic syndrome (MetS) incidence among the US population remain unclear. Objective To investigate intakes and serum concentrations of folate, vitamin B 6 , and vitamin B 12 in associa…