Mandeep Singh Dhillon
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View article: Artificial Intelligence in the Foot and Ankle: The Applications in 2025
Artificial Intelligence in the Foot and Ankle: The Applications in 2025 Open
Artificial intelligence (AI) is the simulation of human intelligence in machines, with machine learning and deep learning (DL) allowing the model to learn complex patterns in the data. The application of AI in medical fields is rapidly pro…
View article: Genomic insights into extrapulmonary tuberculosis reveal enrichment of lineage 2 with high drug resistance in specific clinical phenotypes
Genomic insights into extrapulmonary tuberculosis reveal enrichment of lineage 2 with high drug resistance in specific clinical phenotypes Open
Background Certain M. tuberculosis lineages may preferentially infect extrapulmonary sites, potentially influencing clinical outcomes. Poor drug penetration at these sites may cause treatment failure, even in the absence of resistance. Tim…
View article: Efficacy of Extracorporeal Shockwave Therapy versus Ultrasound Therapy in Adhesive Capsulitis of Shoulder Complex: A Systematic Review and Meta-analysis
Efficacy of Extracorporeal Shockwave Therapy versus Ultrasound Therapy in Adhesive Capsulitis of Shoulder Complex: A Systematic Review and Meta-analysis Open
Physiotherapy treatment of adhesive capsulitis comprises various exercise and electrotherapeutic interventions including Codman’s regime, diathermy, ultrasound therapy, and shockwave. However, there is no existing meta-analytic research co…
View article: Nobody Joked about me... It was my Feeling that now I am Functionally Impaired: A Qualitative Study Exploring the Aftermath of Traumatic Amputation on the Social Life of Lower Limb Amputees
Nobody Joked about me... It was my Feeling that now I am Functionally Impaired: A Qualitative Study Exploring the Aftermath of Traumatic Amputation on the Social Life of Lower Limb Amputees Open
Objectives: A human being is a social animal, and social interactions are pivotal in his life. After traumatic amputation, a normal and able human being becomes disabled for the rest of his entire life. Despite affecting all aspects of lif…
View article: Genetic Association in the Pathophysiology of Degenerative Cervical Disc Disease: Defining Roles
Genetic Association in the Pathophysiology of Degenerative Cervical Disc Disease: Defining Roles Open
Degenerative cervical myelopathy (DCM), encompassing cervical spondylotic myelopathy and posterior longitudinal ligament ossification, is now being documented frequently and significantly burdening the health care systems. The pathogenesis…
View article: Effect of Distal Fragment Length on Construct Stability in an Extra-articular Distal Tibial Fracture Model Fixed With Locked Intramedullary Nailing: A Biomechanical Study
Effect of Distal Fragment Length on Construct Stability in an Extra-articular Distal Tibial Fracture Model Fixed With Locked Intramedullary Nailing: A Biomechanical Study Open
Introduction Fractures of the distal tibia are complex injuries with high complication rates, which include delayed union, non-union, and wound complications like dehiscence and infection. The two commonly employed definite internal fixati…
View article: A Rare Case of Anterior Osteochondroma of Distal Femur with Quadriceps Rupture: A Case Report
A Rare Case of Anterior Osteochondroma of Distal Femur with Quadriceps Rupture: A Case Report Open
Introduction: Despite osteochondromas being fairly common around the knee, cases causing mechanical disruption and being associated with fractures or tears of the Quadriceps are rare. Case Report: A 27-year-old male presented after a fall …
View article: Methods used to Account for Concurrent Analgesic Use in Randomized Controlled Trials of Interventional Pain Treatments: A Meta-Epidemiologic Study
Methods used to Account for Concurrent Analgesic Use in Randomized Controlled Trials of Interventional Pain Treatments: A Meta-Epidemiologic Study Open
Objective The modest effect sizes of most pain treatments make it essential that randomized controlled trials (RCTs) use methods that clearly define treatment effects of interest and consider the role of concurrent treatments. This study a…
View article: Synovial fluid transcriptome dynamics in osteoarthritis progression: Implications in pathogenesis
Synovial fluid transcriptome dynamics in osteoarthritis progression: Implications in pathogenesis Open
Background Osteoarthritis, a degenerative joint disease associated with various pathological manifestations in the joint including cartilage loss, alterations in subchondral bone and synovial inflammation. Objective This study aimed to elu…
View article: Stem Cell Therapies for Cartilage Defects: A Protocol for Systematic Review and Meta-Analysis of Randomized Controlled Trials
Stem Cell Therapies for Cartilage Defects: A Protocol for Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Background Cartilage defects, arising from trauma, degenerative conditions, or genetic factors, pose significant challenges in orthopedic practice due to the limited regenerative capacity of articular cartilage. Traditional treatments like…
View article: Evaluation of the Stability of Internal Fixation Constructs in a Low Distal Tibia Extra-articular Cadaveric Fracture Model: A Comparative Biomechanical Study
Evaluation of the Stability of Internal Fixation Constructs in a Low Distal Tibia Extra-articular Cadaveric Fracture Model: A Comparative Biomechanical Study Open
Introduction Despite the recent advances in implant design, the choice of an internal fixation modality for extra-articular distal tibia fractures remains controversial, and there is sparse literature comparing the stability of intramedull…
View article: Utility of three-dimensional printing in the surgical management of intra-articular distal humerus fractures: a systematic review and meta-analysis of randomized controlled trials
Utility of three-dimensional printing in the surgical management of intra-articular distal humerus fractures: a systematic review and meta-analysis of randomized controlled trials Open
Background: Clinical outcomes after fixation of distal humerus intraarticular fractures are directly related to the quality of reduction. The use of three-dimensional (3D)-printed fracture models can benefit preoperative planning to ensure…
View article: Comparison of Conventional Dose Versus Superdose Platelet-Rich Plasma for Knee Osteoarthritis: A Prospective, Triple-Blind, Randomized Clinical Trial
Comparison of Conventional Dose Versus Superdose Platelet-Rich Plasma for Knee Osteoarthritis: A Prospective, Triple-Blind, Randomized Clinical Trial Open
Background: Confusion persists regarding the ideal dosage of platelet-rich plasma (PRP) injection for knee osteoarthritis (OA). Purpose/Hypothesis: The purpose of the study was to compare the efficacy of 2 different single-injection PRP do…
View article: Embracing Evolution: A New Era in Foot and Ankle Surgery
Embracing Evolution: A New Era in Foot and Ankle Surgery Open
NavigatioN a N d RoboticsAdvancements in navigation and robotics used widely in arthroplasty and spine, have also brought unprecedented precision to foot and ankle surgery.Surgeons can now utilize computerassisted systems to plan and execu…